Gene Information

Name : guaA (Tery_0907)
Accession : YP_720779.1
Strain : Trichodesmium erythraeum IMS101
Genome accession: NC_008312
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1432961 - 1434688 bp
Length : 1728 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGTGTCAACAGAAAAATTTTTCTCACAATTATTTATTAGTTTGGCTAATAACTCAGAAAATAATTGTTACTAACACAAG
AAAATTAATCATTAAAGTCCAACACAATAAAATATTAATCGTGACCCTAACAACACAGACACAAAAAAACTCAGATTCTC
TCACTCAATTTAACCGTCAAATGATCGTAATTTTGGATTTTGGTTCTCAATATTCAGAACTAATTGCCCGCCGAATTCGG
GAAACTCAAGTATATTCAGAGGTTATTTCTTACCGCACAACTGCAGCTAAACTGGCAGATATAAACCCCAAGGGAATCAT
TCTTTCTGGTGGGCCAAATTCTGTTTACGATGAAGGGGCACCTCATTGCGATCCCGAAATTTGGAATTTGGGAATACCCA
TTTTGGGTGTATGCTACGGTATGCAGTTAATGGTAAAACAACTGGGCGGAGAAGTTGAACGCACTCAGTTAGCTGAATAT
GGTAAAGCATCTGTATCAATAGATGATCCTACAGATTTGCTAACAAATATAGAAGAAGGTACAACTATGTGGATGAGTCA
TGGAGATTCTGTCACCAAAATGCCTTCTGGTTTTGAAGTATTAGCTCATACAGATAATACTCCTTGTGGAGCAATAGCTG
ACCACAATAAAAAGCTCTATGGTACTCAGTTTCACCCAGAGGTAGTTCATTCTATTGGTGGTCAAGTATTAATTCGGAAT
TTTGTTTACCATATCTGCAAGTGTGAACCAACCTGGACGACAGAAGCTTTTGTAGAAGAAGCGATTCGAGAAATTAGAGC
TAAAGTAGGGGATAAACGAGTATTATTAGCTCTGTCTGGAGGGGTAGACTCTTCGACTTTAGCATTTTTACTCCATCAGG
CCATTGGAGATAAATTAACTTGTATGTTTATTGACCAAGGGTTTATGCGAAAGTATGAACCAGAGAACTTGGTAAAAATA
TTTCACGAATCTTTTCATATATCAGTTAAATATGTGAATGCTCGCGATCGCTTCTTATCTATACTCAAAGGGGTCAGTGA
TCCAGAAGAAAAACGGAAATTAATCGGCCATGAATTTATTCAAGTATTTGAAGAAGAGTCAAAACGTTTGGGACCTTTTG
ATTATCTAGCTCAAGGTACTCTTTATCCAGACGTGATTGAATCTGCTAATACGAATGTTGACCCCAAAACCGGGGAGCGA
GTAGCGGTTAAAATTAAGAGTCATCACAATGTTGGTGGTTTGCCGAAAGATTTGAGATTTAAATTGGTCGAACCTTTGCG
CAAACTATTTAAGGATGAAGTGAGAAACGTTGGTCGTTCTATTGGCTTACCAGAAGAAATTGTGCGACGACATCCTTTTC
CTGGCCCGGGATTAGCAATTCGGATTTTAGGGGAGGTTACAGACAAACGTTTGAAAATATTACGGGATGCTGATTTTATT
GTGCGCGATGAAATTAGGCAGCAAGGTATGTATCATGATTTTTGGCAAGCGTTTGCTGTTTTGTTACCTATTCAAAGTGT
TGGGGTAATGGGGGATCAACGTACTTATGCTTACCCCATTGTTTTGCGGTTTGTTAAGAGTGAGGATGGAATGACTGCTG
ACTGGTCTCGTGTACCTTATGATTTGTTAGAAACTATTTCTAACCGCATTGTGAATGAGGTTAAGGGAGTTAATCGGGTG
GTGTATGATATTACTTCTAAACCTCCAGGTACTATTGAGTGGGAATAA

Protein sequence :
MCQQKNFSHNYLLVWLITQKIIVTNTRKLIIKVQHNKILIVTLTTQTQKNSDSLTQFNRQMIVILDFGSQYSELIARRIR
ETQVYSEVISYRTTAAKLADINPKGIILSGGPNSVYDEGAPHCDPEIWNLGIPILGVCYGMQLMVKQLGGEVERTQLAEY
GKASVSIDDPTDLLTNIEEGTTMWMSHGDSVTKMPSGFEVLAHTDNTPCGAIADHNKKLYGTQFHPEVVHSIGGQVLIRN
FVYHICKCEPTWTTEAFVEEAIREIRAKVGDKRVLLALSGGVDSSTLAFLLHQAIGDKLTCMFIDQGFMRKYEPENLVKI
FHESFHISVKYVNARDRFLSILKGVSDPEEKRKLIGHEFIQVFEEESKRLGPFDYLAQGTLYPDVIESANTNVDPKTGER
VAVKIKSHHNVGGLPKDLRFKLVEPLRKLFKDEVRNVGRSIGLPEEIVRRHPFPGPGLAIRILGEVTDKRLKILRDADFI
VRDEIRQQGMYHDFWQAFAVLLPIQSVGVMGDQRTYAYPIVLRFVKSEDGMTADWSRVPYDLLETISNRIVNEVKGVNRV
VYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-143 56
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-143 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-143 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-128 51