Gene Information

Name : alr (HS_0939)
Accession : YP_719150.1
Strain : Haemophilus somnus 129PT
Genome accession: NC_008309
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 1039001 - 1040080 bp
Length : 1080 bp
Strand : -
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGAATGTCATACCTCCAACAGCCAGGATTAGTTCTGTTGCATTAAAACATAATATTCAAGTTATTAAGCAAAAAGCCAA
AAACAGTAAAGTCATTGCAATTGTTAAGGCAAATGCTTATGGACATGGTTTGGAGTTCGTTTCCTCTACTCTGCATCATT
TGGTTGACTGTTTTGGTGTGGCTAGATTATCGGAAGCATTACGTCTATGTGCTGAAGGTATTACTAAACCTATTTTATTG
TTAGAGGGTTTTTTTTCCGAGGATGATTTGCCAATTATTGCTGTTAATAATATTCAAACAGTTATCCATAATCAAGAACA
GCTTTATGAGCTTAAGAAAGCCAAGTTGCCGAATAAAATTAAAGTATGGTTGAAAATTGACACAGGAATGCATCGTTTAG
GTGTAGATCTTGAACAGGTAGAAGACTTTTATCAGCAACTTGTTCAATGTTCAAATGTAAAAGAAATTGGGTTTTTGAGT
CATTTTAGCCGGGCAGATGAATTGATGTGTGGTTATACGGAAATTCAGTTAGAGCGTTTTTTACAAGTTACCGAGGGTAA
ACAAGGTGAGCGATCTATTGTTGCCTCATCAGGTATTTTGTTTTGGCAGCAAGCCTATTTAGATTGGATTCGTCCAGGTA
TTATTATGTATGGTATCTCGCCGAATAATACGCCTGCTGAGGTTTATGGATTGATTCCGGTTATGACGTTAACTTCTTCA
TTAATTACTATTAGAAATCATAAAAAAGGTGAACCTGTGGGGTATGGTGGAAGTTGGATTAGTGAGAGAGATACCAAAAT
AGGCGTTGTAGCTATTGGGTATGGAGATGGTTATCCACGGGATATGCCTCAAGGTACACCGGTCTATATTAATGGCAGAA
AAGTACCAATTGTTGGGCGTGTATCGATGGATATGTTAACGGTAGATCTTGGTATTGAGAGTCAAGATAAGGTGGGTGAT
GAAGTTATTTTATGGGGAAAGGAATTACCTATTGAGGAAATTTCTGCAATTAGCGGTATGATAAGCTATGAACTTATCAC
TAAATTAACACCTAGAGTATTGATCGAATATATTGATTAA

Protein sequence :
MNVIPPTARISSVALKHNIQVIKQKAKNSKVIAIVKANAYGHGLEFVSSTLHHLVDCFGVARLSEALRLCAEGITKPILL
LEGFFSEDDLPIIAVNNIQTVIHNQEQLYELKKAKLPNKIKVWLKIDTGMHRLGVDLEQVEDFYQQLVQCSNVKEIGFLS
HFSRADELMCGYTEIQLERFLQVTEGKQGERSIVASSGILFWQQAYLDWIRPGIIMYGISPNNTPAEVYGLIPVMTLTSS
LITIRNHKKGEPVGYGGSWISERDTKIGVVAIGYGDGYPRDMPQGTPVYINGRKVPIVGRVSMDMLTVDLGIESQDKVGD
EVILWGKELPIEEISAISGMISYELITKLTPRVLIEYID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 2e-58 42