Gene Information

Name : nanK (HS_0698)
Accession : YP_718910.1
Strain : Haemophilus somnus 129PT
Genome accession: NC_008309
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : 2.7.1.60
Position : 740934 - 741812 bp
Length : 879 bp
Strand : -
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence : 
ATGCGTTGCTTAGCAATTGATATTGGCGGTACAAAAATTGCAACCGCTGTTGTTGAAGAAAAGAAGCTCTCTAACCGTCA
GCAAATCAGCACGCCACAAGCAGATCCTACAGTCGCATTGCATCATGCCATCAAGCAAATTATGCAAAGTTATGCGGGAC
AGTTTGATGCGGTTGCGGTTGCATCGACAGGCATCATCAACAACGGTATTTTAACCGCACTTAATCCTAAAAATCTCGGT
GGACTGGTTGATTTCCCCTTACAAAAAAGCATTGCTCTCCATACAGATAAACCGATTGGCTTGCTAAATGATGTACAGGC
TGCTGTTTGTGCAGAGTACCAAGATCAAGACCAAAGTGCGGTACGAAATTTTATTTTTATCACGGTATCAACTGGCGTTG
GCGGAGGAATTATTCTCGATGGAAAATTATCCACTGGGCTAAATGGTATAGCCGGTCATATCGGGCATACTTTGGCAGAT
CCGAACGGTCCAATTTGTGGTTGCGGTCGTCGTGGTTGTGTTGAAGCGATTGCGGCGGGGCGAGCAATTGAACGTGAGGC
GAATAAGTGGGAAAAACCTTGTAATCCGAAAGAAGTGTTCAACTTGTTCCGTAAAAATGATGAAAAAGCAACCGCACTTG
TTCGATCCTCAGCAAAAGCTATTGCTAACTTAATTGCTGATATGGTGATTAGTTTAGATGTACAAAAGGTTGTTTTAGGC
GGTAGCGTTGGATTAGCTGAGGGATACTTATCCCTCGTTCAAGAATATTTAACCGACATGCCAAAATTTTATCACTGTAT
TTTGGAGCCGGCTAAATACGGTGCCGATGCAGGTTTAATTGGTGCGGCTTATTGGATGAAAATGCAACAAACCCCATAA

Protein sequence : 
MRCLAIDIGGTKIATAVVEEKKLSNRQQISTPQADPTVALHHAIKQIMQSYAGQFDAVAVASTGIINNGILTALNPKNLG
GLVDFPLQKSIALHTDKPIGLLNDVQAAVCAEYQDQDQSAVRNFIFITVSTGVGGGIILDGKLSTGLNGIAGHIGHTLAD
PNGPICGCGRRGCVEAIAAGRAIEREANKWEKPCNPKEVFNLFRKNDEKATALVRSSAKAIANLIADMVISLDVQKVVLG
GSVGLAEGYLSLVQEYLTDMPKFYHCILEPAKYGADAGLIGAAYWMKMQQTP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 2e-28 45
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 2e-29 43
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 2e-29 43
VPI2_0030 ACA01847.1 ROK family protein Not tested VPI-2 Protein 8e-29 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
nanK YP_718910.1 N-acetylmannosamine kinase VFG1115 Protein 7e-30 43