Gene Information

Name : smpB (HS_0473)
Accession : YP_718684.1
Strain : Haemophilus somnus 129PT
Genome accession: NC_008309
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 504384 - 504866 bp
Length : 483 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGACAAAGAAAAAAGCAAAGGTAGCATCTAATACGATTGCCTTAAATAAACGAGCAAGACACGATTATTTTATTGAAGA
TGAAATCGAAGCCGGTCTTTCTTTGCAAGGCTGGGAAGTTAAATCGATGCGTGCAGGTAAGGCGAGTATTGGCGATAGTT
ATATTATTTTTAAGCATGGTGAGGCATATTTATTTGGTGCAACCATTCAGCCGTTAAGTGTTGCTTCAACGCATATTGTT
TGCGATCCCACAAGAACACGTAAACTTTTATTAAACCAGAAAGAGTTGGCTTCATTATTTGGTAAAGCAAATCGAGATGG
TTTCACTATTGTTGCACTTTCATTATATTGGAAAGGTCCTTGGGCAAAGGTGAAAATAGGTTTAGCAAAAGGGAAAAAAT
TACATGATAAGCGTGAAGATATTAAAGATCGTGAATGGAAAGTAACGAAAGATCGCATTATGAAAAATGCACAGCGAGGT
TAA

Protein sequence :
MTKKKAKVASNTIALNKRARHDYFIEDEIEAGLSLQGWEVKSMRAGKASIGDSYIIFKHGEAYLFGATIQPLSVASTHIV
CDPTRTRKLLLNQKELASLFGKANRDGFTIVALSLYWKGPWAKVKIGLAKGKKLHDKREDIKDREWKVTKDRIMKNAQRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 1e-49 66
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 2e-22 46
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 2e-17 43