Gene Information

Name : murD (HS_0356)
Accession : YP_718566.1
Strain : Haemophilus somnus 129PT
Genome accession: NC_008309
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 362739 - 364049 bp
Length : 1311 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGACTAATCAATATCAAAACAAAAATATCTGCGTAGTCGGATTAGGTAAAACAGGATTGTCTTGCGTTGATTTCTTGTT
ACGGCAGCAAGCAAATGTACGTGTCATTGATACTCGTCAACAACCGACGGGAGCAGAAAAATTACCTGAAAATGTCCCCT
TACATACAGGAAGCTTAAACCAACAATGGCTACTTGAAGCTGATCTCATTGTGATTAGCCCTGGGCTTTCTGTTAAAACA
CTTGAAATTCAGACCGCACTTCAGGCCGGTGTAGAGGTTGTCGGTGATATTGAATTATTTTGTCGTCACGCCAATAAGCC
AATTATTGCTATTACAGGCTCAAATGGTAAGAGTACCGTGACTACATTGGTCAGTGAAATGGCGAAAGAGGATGGCTTAA
AAGTTGGAATGGGGGGAAATATTGGTATTCCTGCTCTTGAGTTATTGCAACAAGATTATGATATCTATGTTTTAGAGCTA
TCAAGTTTTCAACTGGAGACGACTTATAGTTTGAAAGCGACAGCCGCAACGATTTTAAATATTAGTGAAGATCATATGGA
TCGTTATCTCGATATTGAAGATTATCGCCAAGCCAAATTGAGAATTTATGAAAATTGTCAACGTGCGGTAATAAATGCCG
AAGATGTATTAACAACAACGGAAGATTTAAAGTCTCCAATTACTTTTGGAGAAAGTCAGGCAGATTATTGGCTAAAAACG
GAAAATGGCAAGCAATATTTAATGGCAAAAGAGCGGTTAATTTTACCTTGTGATGAAATGAAATTGGTAGGTCGTCATAA
TTATATGAATGCGTTGGCGGCCAGTGCGTTGGTTCAGGCTGTCGACATAAGTTTTACTGCAATTCGGACCGCACTTCGTA
AATTTACCGGTTTAGCTCATCGCTTTCAGTTAGCATATCAGAAAGATGATGTACGTTGGATTAATGATTCGAAGGCAACC
AATGTTGGAAGTACAGTTGCTGCACTGACCGGTTTGTATGTAGCTAATAAATTACATTTATTGTTGGGGGGGGATGGTAA
ATCCGCAGATTTTTCGGAATTGGCAACATTAATTAATCAACCCCATATTTATTGCTATTGTTTTGGGCAAGATGGTAAAG
AACTTGCCGCACTATCAGTGCAAAGTCAGTTATTTGATACGATGGAACAGGCAATAGAAGCTATTCGTCCGAATTTACAG
CAAGGTGATATGGTGCTTTTATCACCGGCTTGTGCAAGTTTGGATCAATTTAAATCCTTTGAACATCGAGGTGATGTTTT
TAGTGATTTAGCGAAGTTGGCACAGGGTTAA

Protein sequence :
MTNQYQNKNICVVGLGKTGLSCVDFLLRQQANVRVIDTRQQPTGAEKLPENVPLHTGSLNQQWLLEADLIVISPGLSVKT
LEIQTALQAGVEVVGDIELFCRHANKPIIAITGSNGKSTVTTLVSEMAKEDGLKVGMGGNIGIPALELLQQDYDIYVLEL
SSFQLETTYSLKATAATILNISEDHMDRYLDIEDYRQAKLRIYENCQRAVINAEDVLTTTEDLKSPITFGESQADYWLKT
ENGKQYLMAKERLILPCDEMKLVGRHNYMNALAASALVQAVDISFTAIRTALRKFTGLAHRFQLAYQKDDVRWINDSKAT
NVGSTVAALTGLYVANKLHLLLGGDGKSADFSELATLINQPHIYCYCFGQDGKELAALSVQSQLFDTMEQAIEAIRPNLQ
QGDMVLLSPACASLDQFKSFEHRGDVFSDLAKLAQG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 5e-63 43
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 5e-63 43