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Name : topA (HS_1737) Accession : YP_719942.1 Strain : Haemophilus somnus 129PT Genome accession: NC_008309 Putative virulence/resistance : Unknown Product : DNA topoisomerase III Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : 5.99.1.2 Position : 1966695 - 1968725 bp Length : 2031 bp Strand : + Note : decatenates replicating daughter chromosomes DNA sequence : ATGAAACTCTTTCTATGCGAAAAACCCAGTCAGGGACGGGATATTGCAAAAGTGCTGGGGGCAACACAAAAAGGGGAGGG TTATTTATCAACCGCTGATGGCACAATTGTTGTTACTTGGGCGAGAGGGCATTTAGTTGAGCATTTCTCGCCGGAACAAT ACGATCCCGCACTTAAGGCATGGCGATTAGATACTCTCCCGATTATCCCTTCCCAATGGCAAGTTTCCCCTAAACCTGAT GCAAAAAAAGAATATAAAACCGTGATGACATTGCTGAAAAAAGCACGCACGGTAGTGATTTCAACTGATATTGATCGAGA AGGGGAAACTATTGCCCGTGAATTATTAGACCTTGCCGGTTATCGTGGACATATTCAGCGGCTGTGGATCACCGCACTTG ATGAAATCAGTGTGCGTAAAGCACTCAGCCGGCTTAAAACCAATGAAGAAACCTTGCCTCTTTATTATGCCGGGCTTGCT CGTAGTCGGGCAGATTGGTTAATCGGAATGAATTTTAGTCGAATGTTTACTCTTTTGGCACAACAACAAGGTTATCAAGG TCCGCCACTTTCGGTAGGGCGAGTGCAAAGCCCCACATTGGCACTGGTGGTGAATCGAGATAAGGAAATTGCTCATTTTG TTCCAACCTATCATTATGCATTGATGGTACAAGTCTGTGGAACCAATGCTCAGTCTTTTGAGGCAAGCCTTTTGGTTCCT GAACAATATTGTGATGAAGAGGGGCGTTGTTTAGAGATAAAGGTGCTTCAGCAAGCGGAACAACAGATTCGTCAGGCGGG ACAAGTGTGTGTGCAGAATGTAGAAACGAAGCGAGAAAAAGAAAGTCCGCCGTTACTTTTTGCATTAAGTGATTTGCAGG CGGAATGTAATCGCCTCTATGATTTAGGTACACAACAAGTGCTTGATATTGCACAATCCCTCTATGAAAAACACAAAGCA ACTACCTATCCGCGTACGGATTGCGGTTATCTTCCTGAAGCACAATTACTTGAAGTGCCTCAGGTCATTAATAGTCTGAT GCAGTCAGATGCCAAGTTACAGCCTTTGCGAGTACAGCTTAATTTGAGCCAAAAATCCCGTGCGTGGAATGATAAAAAAA TTACCGCTCACCATGGGATTATTCCCACAACACAGCCGGTTGATATTGCTAAAATGAACGAGAATGAGTTTAAAGTTTAT GACTTAATTCGTCGGCGTTATCTCGCACAATTTCTACCGCACTTTGAAGTGGATAAAACCCGAGTTAGGTTATCTTGTGG AGAGCATCAATGCATTGCAAAAGGTCAAGTGATTGTGAGTGCAGGTTGGAAAGCCTTGTTTCGAGCGTCTAAAGAAGAGC AGGGAGAGAAACAAGGTTTGCCAATACTGAATAGTGGGCAAATGTTGAAGGTGATGAATACGGAAATAAAATCACTTAAA ACCACACCGCCTGCACACTATACAGAAGGTACACTGCTCACGGCAATGGTGAATGTCGCCCGTTTTGTTACAGATGAACG GCTAAAGAAACAATTACGTGAAACGGAAGGACTGGGGACAGAGGCTACTCGGGCAAGTATTATGAAAACCCTTTATGACC GCGGTTATATCAAGAAAAAAGGGAAATCCATTGTGGCGACAGACGCAGGCGTGATGTTGATTGATAATTTACCGACGGTA TTAAAAGATCCGGGGTTAACGGCATTATGGGAACAAGCATTAAATCAAATTGCCGAGAACCAAATGAGCTTGCAGGAATT TATGCAAAAGCAAGAACAGTTTGTTCTCCATCTTATTCAAACCTGTGGACATCAAGGTATCAAAATGGGCAATATAGATA TTAAAAAATGCCCACAATGCGGTAAGCCACTTCGAAAAATGAAAGGGAAAAATGGAGATTTCCTAGGTTGTACGGGCTAT CCGAAATGCAAATATATTGAATCCGGTGCGAAAAGAAAAACATCTGCCGGAAAAGTTACCCCTATCAACCTTTCTCAACA ATTTGCAAATTTGCGTCAAGCCGTCAAATAA Protein sequence : MKLFLCEKPSQGRDIAKVLGATQKGEGYLSTADGTIVVTWARGHLVEHFSPEQYDPALKAWRLDTLPIIPSQWQVSPKPD AKKEYKTVMTLLKKARTVVISTDIDREGETIARELLDLAGYRGHIQRLWITALDEISVRKALSRLKTNEETLPLYYAGLA RSRADWLIGMNFSRMFTLLAQQQGYQGPPLSVGRVQSPTLALVVNRDKEIAHFVPTYHYALMVQVCGTNAQSFEASLLVP EQYCDEEGRCLEIKVLQQAEQQIRQAGQVCVQNVETKREKESPPLLFALSDLQAECNRLYDLGTQQVLDIAQSLYEKHKA TTYPRTDCGYLPEAQLLEVPQVINSLMQSDAKLQPLRVQLNLSQKSRAWNDKKITAHHGIIPTTQPVDIAKMNENEFKVY DLIRRRYLAQFLPHFEVDKTRVRLSCGEHQCIAKGQVIVSAGWKALFRASKEEQGEKQGLPILNSGQMLKVMNTEIKSLK TTPPAHYTEGTLLTAMVNVARFVTDERLKKQLRETEGLGTEATRASIMKTLYDRGYIKKKGKSIVATDAGVMLIDNLPTV LKDPGLTALWEQALNQIAENQMSLQEFMQKQEQFVLHLIQTCGHQGIKMGNIDIKKCPQCGKPLRKMKGKNGDFLGCTGY PKCKYIESGAKRKTSAGKVTPINLSQQFANLRQAVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| topB1 | YP_005176228.1 | DNA topoisomerase III | Not tested | ICEPmu1 | Protein | 0.0 | 63 |
| topB | AAN62317.1 | putative DNA topoisomerase III | Not tested | PAGI-3(SG) | Protein | 4e-154 | 50 |
| topB | NP_458624.1 | topoisomerase B | Not tested | SPI-7 | Protein | 2e-152 | 49 |
| topB | NP_807836.1 | DNA topoisomerase III | Not tested | SPI-7 | Protein | 2e-152 | 49 |
| topB | AAF14809.1 | topoisomerase B | Not tested | SPI-7 | Protein | 2e-152 | 49 |
| pph56 | CAI36097.1 | Topoisomerase IA | Not tested | PPHGI-1 | Protein | 1e-154 | 49 |
| topB | AAN62194.1 | putative DNA topoisomerase III | Not tested | PAGI-2(C) | Protein | 2e-163 | 49 |
| PMI2630 | YP_002152332.1 | DNA topoisomerase III | Not tested | Not named | Protein | 1e-140 | 48 |
