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Name : leuS (HS_1557) Accession : YP_719762.1 Strain : Haemophilus somnus 129PT Genome accession: NC_008309 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 1753538 - 1756120 bp Length : 2583 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAAGAACAATATCGTCCTGATCTTATCGAAGCAGACGTACAGAAATATTGGGCTGAAAAGAAAACATTCAAAGCCGT TAAAGATCCTTCCAAAGAAAAATATTATTGTCTTTCCATGTTTCCTTATCCTTCCGGTCGTTTACACATGGGGCATGTTC GTAACTATACCATTGGCGATGTTATCTCCCGTTATCAACGAATGAACGGTAAAAATGTTTTACAGCCTATGGGCTGGGAT GCTTTTGGGTTGCCAGCAGAAGGTGCGGCAATTAAAAATAAAACCGCACCGGCAAAATGGACTTATGAAAATATCGAATA CATGAAAAATCAGCTTAAAGTGTTGGGCTTCGGATTTGACTGGGATCGTGAAATTACCACTTGTAAACCTGAATATTATA AATGGGAGCAATGGTTTTTTACTGAGTTGTATAAAAAAGGGTTAGTGTATAAAAAAACCTCAACAGTAAACTGGTGTCCG AATGATGAAACCGTTCTGGCAAATGAGCAAGTACATGAGGGGTGTTGTTGGCGTTGCGATACCCCTGTGGAGCAAAAAGA AATTCCGCAATGGTTTATTAAAATTACGGACTATGCTGAACAATTATTAAGTGATTTAGATCAGCTTCCTGAATGGCCGG ATATGGTAAAAACTATGCAACGTAACTGGATAGGTCGCTCCGAAGGGGTTGAAATTACCTTTAACGTTGCTCATTCAGAT CAAACCTTAACAGTTTATACAACCCGCCCGGATACTTTCTATGGTGTTTCTTATTTAGCGGTTGCGGCGGCACATCCGTT AGCTGAAAGTGCGGCAAAAAATAATCCTGAATTGGCTGCTTTTATTCACGAGGCAAAAAATACCAAAGTGGCTGAAGCGG AACTTGCCACAATGGAGAAAAAAGGCATGGCAACAGGATTGTATGCCGTTCATCCGATGACAGGTAAACAGTTACCGATT TGGGTAGCAAATTTTGTGTTAATGCACTACGGTACAGGTGCGGTTATGGCAGTTCCTGCACATGATCAACGTGATTATGA ATTTGCACAAAAATATCAATTGCCTTTATTCCCCGTGATTAAGCCGGCGGATAATTCTGCATGGGATTTTTCAAAACAGG CTTATACTGAGCATGGTATCACCATTAATTCTGCTGAGTTTGACGGTTTGGATTTTGAGGCAACCTTTAACGGTATTGCG GATAAACTTGAAAAAATCGGTGTAGGAAAACGCCAAGTAAACTATCGTTTACGTGACTGGGGAGTTTCCCGTCAACGTTA TTGGGGAGCACCAATTCCAATGCTGACACTGGAAAATGGTGATGTTGTAGTTGCCCCATTACAGGACTTACCAATTGTTT TGCCGGAAGATGTAGTCATGGACGGAGTAAAAAGTCCGATTAAGGCTGATCCTGAATGGGCAAAAACCACTTATAACGGA CAAGCAGCATTAAAAGAAACGGATACCTTTGATACTTTCATGGAATCTTCTTGGTACTATGCACGCTATACCTCTCCACA ATATCAACAAGCGATGTTAGATGCAGATGAAGCGAATTATTGGCTACCGGTGGATCAATATATTGGTGGCATTGAACATG CAACCATGCACCTATTATATTTCCGTTTCTTTCATAAATTGTTGCGAGATGCCGGTTTCGTAACTTCTGATGAGCCAAGC AAAAAATTACTGTGTCAAGGTATGGTACTTGCAGACGCATTTTATTACACCAGCCCAACCAATGAGCGTATTTGGGTATC GCCGACAAAAGTAACGTTAGAGCGTGATGAGAAAGGTCGTATTATCAAAGCTGTTGATGATGAAGGTCACGAGCTTGTTC ACAGTGGTATGACCAAAATGTCTAAGTCCAAAAATAATGGTATTGATCCGCAAGAAATGGTGGAGAAATACGGTGCAGAT ACAGTCCGTTTATTTATGATGTTTGCTTCGCCGGCAGAAATGACACTCGAATGGCAAGAGTCAGGAGTAGAGGGGGCAAA TCGTTTCTTACGCCGCCTATGGAATTTAGTTTTTGAATACAATCAAAATCCGGCACAAACCGCATTAGATCCTACCGCTC TTTCAGTCGAACAAAAAGCATTGCGTCGTGATGTACATAAAACTATTGCAAAAGTGAGCGATGATATTGGTCGTCGCCAA ACATTCAATACCGCAATTGCGGCAATCATGGAATTAATGAATAAACTCACCAAAGCATCATTATCCAATGAGCAAGATCG TGCAGTAATGGCAGAAGCATTGAATGCCGTTGTGCGTATGCTTTATCCGATTACACCACATATTTGTTTCCAACTTTGGC AAGACTTAGGTAACGAAAGTACGATTGATTTTGCACCTTGGGTGATAGCCGATGCTGAAGCTATGGTTGAAGATGAAAAA TTGGTTGTGATACAAGTGAATGGTAAAGTTCGTGCTAAAGTAACCGTTCCTGCTGATATGTCGGAAGATGAAATTAAACA AGTTGCTTTAGCAGAAGAAAATGTACAAAAATTCTTGAATGGTTTAACTGTAGTTAAGACCATTTATGTACAGGGTAAAT TATTTAGCTTTGTAGCAAAATAA Protein sequence : MQEQYRPDLIEADVQKYWAEKKTFKAVKDPSKEKYYCLSMFPYPSGRLHMGHVRNYTIGDVISRYQRMNGKNVLQPMGWD AFGLPAEGAAIKNKTAPAKWTYENIEYMKNQLKVLGFGFDWDREITTCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCP NDETVLANEQVHEGCCWRCDTPVEQKEIPQWFIKITDYAEQLLSDLDQLPEWPDMVKTMQRNWIGRSEGVEITFNVAHSD QTLTVYTTRPDTFYGVSYLAVAAAHPLAESAAKNNPELAAFIHEAKNTKVAEAELATMEKKGMATGLYAVHPMTGKQLPI WVANFVLMHYGTGAVMAVPAHDQRDYEFAQKYQLPLFPVIKPADNSAWDFSKQAYTEHGITINSAEFDGLDFEATFNGIA DKLEKIGVGKRQVNYRLRDWGVSRQRYWGAPIPMLTLENGDVVVAPLQDLPIVLPEDVVMDGVKSPIKADPEWAKTTYNG QAALKETDTFDTFMESSWYYARYTSPQYQQAMLDADEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGFVTSDEPS KKLLCQGMVLADAFYYTSPTNERIWVSPTKVTLERDEKGRIIKAVDDEGHELVHSGMTKMSKSKNNGIDPQEMVEKYGAD TVRLFMMFASPAEMTLEWQESGVEGANRFLRRLWNLVFEYNQNPAQTALDPTALSVEQKALRRDVHKTIAKVSDDIGRRQ TFNTAIAAIMELMNKLTKASLSNEQDRAVMAEALNAVVRMLYPITPHICFQLWQDLGNESTIDFAPWVIADAEAMVEDEK LVVIQVNGKVRAKVTVPADMSEDEIKQVALAEENVQKFLNGLTVVKTIYVQGKLFSFVAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 1e-159 | 41 |
