Gene Information

Name : lysS (HS_1477)
Accession : YP_719687.1
Strain : Haemophilus somnus 129PT
Genome accession: NC_008309
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1669414 - 1670922 bp
Length : 1509 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGACAGAAATAATTCAAGAATTGGATCTCAATGGCGAAATGTTGGTTCGTCGTGAAAAATTAGCTGCGTTAAGAGCAAA
AGGCAACGCCTTTCCAAATACATTCCGTCGCAATGCTTTAGCACAGGACTTACATACACAATATGATGAAATTGAAAGTG
AGAGCTTAAAAACACAGGGAATTGAAGTAAAAGTGGCGGGGCGTATTATGACTCGTCGTGTCATGGGTAAAGCAACCTTT
ATCACATTGCAAGACATGAGCGGAAAAATTCAACTTTATGTTGCTCGTGATAACCTAGCTGAAGGTGTTTATACTGATGA
TGTGGGCAATTGGGATTTAGGGGATATTGTTGGTGTAAAAGGTACTTTATTTAAAACTAAAACCAATGAGTTGACAATAC
GTGCAACGGAGGTTCACTTATTAACTAAAGCATTACGCCCGCTTCCTAATAAATTTCATGGACTGAGCGATCAAGAAACT
CGTTACCGTCAACGCTACTTAGATTTAATTGCTAATGAAGATTCACGCCGCACTTTTATTATTCGATCTAAAGTAATCGC
AGGCATTCGTGAATATTTCATTTCCAAGGGATTTATGGAAGTAGAAACCCCTATGTTACAAATTATTCCTGGCGGTGCAT
CTGCACGTCCATTTATTACTCATCACAATGCGTTAGATGTGGATATGTATTTACGTATTGCACCTGAACTTTATTTAAAA
CGTTTGGTAGTTGGCGGTTTTGAACGTGTATTCGAGTTAAATCGTAACTTCCGCAATGAAGGTGTTTCTATTCGCCATAA
CCCTGAATTTACTATGTTGGAATACTACCAAGCCTATGCGGATTACCACGATTTAATGGACAATACAGAAGAACTTTTAC
GCAAATTAGCACTGGATATTTTAGGTACGACCATTGTTCCTTACGGCGATTTAAAATTCGATTTCGGCAAACCGTTTGAA
CGTATTACCATGCACGAGGCAATCTTAAAATACGGTGCCGAGCAAGGTATTGTGAAAGAAGATTTATACGATTTCGATCG
TGCTGTTGCAATAGCACAAAAATTGGGTATCGAAGTACAAAAATCATGGGGGCTAGGTAGCTTAGTCAATGCAATTTTTG
AAGAAGTTGCTGAACATCATTTAATTCAACCAACTTTCTTAATGGCTCATCCAGCAGAAATCTCCCCTTTAGCACGCCGC
AATGATGAAAATCCTGACGTAACAGACCGCTTTGAACTATTTATCGGAGGACGTGAGATCGGTAACGGTTTCTCAGAATT
AAATGATGCAGAAGATCAAAATGAGCGTTTTGATGCACAGGTTGCAGCAAAAGAAGCTGGTGACGATGAAGCTATGTTTA
AAGATGAAGATTTTGTTACCGCACTTGAGCATGGATTGCCACCAACGGCTGGTGAGGGTTTAGGAATTGATCGTCTAGCG
ATGTTATTTGCCAACGCTAACTCAATTCGTGATGTGATTTTATTTCCTGCAATGAAGACAAAAAACTAA

Protein sequence :
MTEIIQELDLNGEMLVRREKLAALRAKGNAFPNTFRRNALAQDLHTQYDEIESESLKTQGIEVKVAGRIMTRRVMGKATF
ITLQDMSGKIQLYVARDNLAEGVYTDDVGNWDLGDIVGVKGTLFKTKTNELTIRATEVHLLTKALRPLPNKFHGLSDQET
RYRQRYLDLIANEDSRRTFIIRSKVIAGIREYFISKGFMEVETPMLQIIPGGASARPFITHHNALDVDMYLRIAPELYLK
RLVVGGFERVFELNRNFRNEGVSIRHNPEFTMLEYYQAYADYHDLMDNTEELLRKLALDILGTTIVPYGDLKFDFGKPFE
RITMHEAILKYGAEQGIVKEDLYDFDRAVAIAQKLGIEVQKSWGLGSLVNAIFEEVAEHHLIQPTFLMAHPAEISPLARR
NDENPDVTDRFELFIGGREIGNGFSELNDAEDQNERFDAQVAAKEAGDDEAMFKDEDFVTALEHGLPPTAGEGLGIDRLA
MLFANANSIRDVILFPAMKTKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-154 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_719687.1 lysyl-tRNA synthetase VFG1668 Protein 3e-154 64