Gene Information

Name : metB (HS_1345)
Accession : YP_719557.1
Strain : Haemophilus somnus 129PT
Genome accession: NC_008309
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1536989 - 1538098 bp
Length : 1110 bp
Strand : -
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
ATGACACAACAATATGCTCTAGATACATTACTGGCTCAGACCGGTAATAGAACAGATGAAAGAACCGGTGCGGTATCTAC
GCCGATTTTTCTTTCCACTGCTTATGGTCATCATGGAATTGGTGAAAGTACGGGATTTGATTATACCCGCACTAAAAATC
CAACGAGAACGGTATTAGAAGAAACAATTGCAAAATTAGAAGGTGGAGATCGTGGATTTGCCTGTTCTTCAGGAATGGCG
GCTATTCAATTATTGATGAACTTATTTGCGTCACCTGATGAATGGATTGTTTCCAGCGATGTTTATGGCGGAACTTATCG
CCTATTGGATTTTGCACATAAGAATATTCATGGTGTCAAACCTGTTTATGTCAATACAGCTTCAAGTGAAGAAATTGAAA
AGGCAATCACTGAGAATACAAAGGCGATTTTTGTTGAAACACCATCGAATCCGTTAATGGAAGAATGTGATGTGGCAGAA
ATTGCGAAAATAGCTAAAAAATACAAATTGCTATTGATTGTAGACAATACTTTTTTAACTCCTGTTTTATTTAGACCAAT
GGAACATGGTGCAGATATTGTTATTCATAGTGGAACAAAATATATTGCTGGTCATAACGACACATTGGTAGGGTTAATTG
TTGCCAAAGGGCAAGAGATCTGTAACCGCTTATATTATATTCAAAATGGTGCAGGTCCCGTATTATCACCTTTTGATTCT
TGGTTGACCATTCGAGGCATGAAGACACTTGCATTGCGAATGGAACGTCATCAGAAAAATGCACAGGAATTGGCAAACTT
TTTAAGAGAACAGCCACAAGTAAAAGATGTGTTATATCCAAATAAAGGAGGGATGCTATCTTTTCGTCTTCAAAATGAAA
ATTGGGTAAATCCTTTTCTTAAAGCAATGAAGTTAATTACTTTTGCTGAGAGTTTAGGCGGTACGGAAAGTTTCATTACG
TATCCGGCGACACAAACGCATATGGATATTCCTGAGGTTGAACGTGTTGCTCGAGGTGTATGCAATCGTTTACTACGGTT
TTCTGTAGGATTGGAGAATGTAGAAGATATTAAAGCGGATTTATTACAGGCATTTTCTCAACTAAAGTAA

Protein sequence :
MTQQYALDTLLAQTGNRTDERTGAVSTPIFLSTAYGHHGIGESTGFDYTRTKNPTRTVLEETIAKLEGGDRGFACSSGMA
AIQLLMNLFASPDEWIVSSDVYGGTYRLLDFAHKNIHGVKPVYVNTASSEEIEKAITENTKAIFVETPSNPLMEECDVAE
IAKIAKKYKLLLIVDNTFLTPVLFRPMEHGADIVIHSGTKYIAGHNDTLVGLIVAKGQEICNRLYYIQNGAGPVLSPFDS
WLTIRGMKTLALRMERHQKNAQELANFLREQPQVKDVLYPNKGGMLSFRLQNENWVNPFLKAMKLITFAESLGGTESFIT
YPATQTHMDIPEVERVARGVCNRLLRFSVGLENVEDIKADLLQAFSQLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-60 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-61 41