Gene Information

Name : serS (HS_1075)
Accession : YP_719287.1
Strain : Haemophilus somnus 129PT
Genome accession: NC_008309
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1191644 - 1192933 bp
Length : 1290 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATCCAACTTTATTACGCAATAATCTTTCTGAAATTGCGGAAAAATTAAAAGTAAGACGTGGCTTTATTCTCGA
CGTAAATAAATTTTCACAATTAGAAGAACAACGTAAGACTTTACAAATTAAAACGGAAACTTTACAAGCCGAACGTAACT
CTCGCTCAAAAACAATTGGTGCGGCAAAAGCCAGAGGAGAAGATATTTCTACTTTATTGGCAGAAGTTGATCATATGGGA
GCCGAATTAAATACTGTCAAAGAAGAATTAGCGAATGTATTAACGGAAATTGAGCAATTGGCATTAACAATTCCCAATAT
TCCTGCTGATGAAGTACCTTTAGGAAAAGATGATTCTGATAATAAAGAAGTTTTTCGTTGGGGAACACCAAAAAAATTTG
ATTTTGAAGTGAAAGATCATGTTGCCTTAGGGGAAATATTAGGTGGGTTAGATTTTGCTGCTGGTGTTAAATTAAGTGGT
GCTCGTTTTGCCGTAATAAAAGGGCAAATTGCAAGAATGCATCGAGCCTTGGCACAGTTTATGCTAGATTTACATACTGA
GCAACATGGCTATACAGAGGCTTATGTACCTTATTTAGTCAATCATGCAACACTTTATGGAACGGGGCAGTTACCAAAAT
TTGGTGAGGAGTTATTTCATATAAAACCCCTAGAAAATGAACAGACTTATGCGTTAATCCCTACCGCCGAAGTGCCTGTA
ACAAACTTAGTTCGAGATGAAATCATCGATGAAGCTGATTTACCAATAAAAATGACCGCACATACGCCTTGTTTCCGTTC
TGAAGCAGGTTCTTACGGTCGTGATACTCGAGGTTTAATCCGTATGCATCAATTTGATAAGGTTGAATTAGTACAAATTG
TTGAACCGGAAAAATCAATGGAAGCACTGGAAGAATTGACAAATCAGGCAGAAAAAGTATTACAACTTTTAAATTTACCT
TATCGTAAAGTTTTATTGTGTACAGGCGACATGGGATTCGGAGCTACTAAAACATATGATTTGGAAGTATGGATTCCGGC
ACAAAATACGTATCGTGAAATTTCTTCTTGCTCAAATATGTGGGATTTCCAAGCACGTCGTATGCAAGCCCGTTGTCGTG
CAAAAGGCGATAAAAAAACACGCTTAGTACATACTTTAAATGGATCGGGACTAGCTGTTGGTCGCACTTTAGTTGCCATT
CTTGAAAATTATCAAAATGCAGATGGCTCTATTACCGTACCGGAAGTATTACGCCCTTATATGAATGGAATAGAAATTAT
TGGTAAATAA

Protein sequence :
MIDPTLLRNNLSEIAEKLKVRRGFILDVNKFSQLEEQRKTLQIKTETLQAERNSRSKTIGAAKARGEDISTLLAEVDHMG
AELNTVKEELANVLTEIEQLALTIPNIPADEVPLGKDDSDNKEVFRWGTPKKFDFEVKDHVALGEILGGLDFAAGVKLSG
ARFAVIKGQIARMHRALAQFMLDLHTEQHGYTEAYVPYLVNHATLYGTGQLPKFGEELFHIKPLENEQTYALIPTAEVPV
TNLVRDEIIDEADLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVELVQIVEPEKSMEALEELTNQAEKVLQLLNLP
YRKVLLCTGDMGFGATKTYDLEVWIPAQNTYREISSCSNMWDFQARRMQARCRAKGDKKTRLVHTLNGSGLAVGRTLVAI
LENYQNADGSITVPEVLRPYMNGIEIIGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 8e-108 56