Gene Information

Name : cadA (HS_1007)
Accession : YP_719218.1
Strain : Haemophilus somnus 129PT
Genome accession: NC_008309
Putative virulence/resistance : Virulence
Product : L-lysine decarboxylase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : 4.1.1.18
Position : 1108445 - 1110571 bp
Length : 2127 bp
Strand : +
Note : -

DNA sequence :
ATGAAACAAATACTCATTGGATACTCAATGTATAATGATCATTTGCAGAATTTAATTTCAGCATTGGAAGAAAAGGGGTA
TAAAACTACCGCAGTAGATGGTCATCAAGAAATTTTGCATGCAGTGAAAAATAATGCAAGTATCATTTCTGTGATATTAA
GCAATGATATTATAGATAAAGATCTGACTGACAAGATACTTTTACTAAATGAGGACCTGCCAATCTTTTCGTTAAAAGAC
ACAGATGATTTAAACGAGAATTTAGATTTTGCAACAATTGGGCACCATGTTCAGTTTGTTGACTGCAATTTATATACTCT
CGATGAGATTATTCATAAGATAGAAAGAGCGGTAGAAAAATATTTTGATTCAATTACACCACCACTTACTAAAGCATTAT
TTAAATATGTTAATGAGGATAAATATACATTTTGTACCCCAGGACATATGGGAGGAACAGCATTTTTACGTTCTCCGATA
GGTAGTGTTTTCTATGATTTTTTTGGTAAAAATACCTTTAAATCTGATATTTCGGTCTCTGTTGGTGAGTTGGGTTCTTT
ATTGGATCATAGTGGACCACATAAGGAAGCTGAAAAGTACATTGCAAATGTATTTAATGCAGATAGAAGTTATATTGTGA
CTAACGGAACCTCAACCGCAAATAAAATTGTTGGTATGTATTCTGCTCCCTCAGGTAGCACTGTTTTAATTGATCGTAAT
TGTCATAAATCCTTGACTCATTTACTTATGATGAGCGATGTTACACCGATTTACTTAAAACCGACAAGAAATGCTTATGG
TTTACTTGGTGGCATTCCTGAGCAAGAGTTCTCAAAATCTGCAATAGAGAAAAAATTAGCAGACATTGATAATCCGAATT
GGCCTGTCCATGCTGTTATTACTAATTCAACTTATGACGGTCTATTTTATAACACAGACAAAATTAAGGAAACTCTTGAT
GTAAAATCTATTCATTTCGATTCAGCATGGGTTCCATATACTAATTTCAATCCGATTTATGAAGGTAAAACAGGTATGGG
CGGTAAGCGAGTTGAAGATAAAATTATCTATGAAACACAATCCACTCACAAATTACTTGCTGCATTTTCTCAAGCTTCAA
TGATCCATATTAAAGGTCAAATAAATGAGGAAACTTTCAATGAAGCCTATATGATGCATACTTCAACCTCTCCACACTAT
GGTATTGTATCGTCTACGGAAGTGGCTGCAGCCATGATGAAAAACAATACAGGAAAACAATTACTGCAAGATGCTATAAC
AAGAGCGGTCAGATTTCGTAAAGAAATTAAGCAACGCATGCGAGAATCTCAATCTTGGTATTTTGATGTATGGCAACCTG
AAAATATTTCTTCGACAGAGTGTTGGGAATTAAAACCGGGTGAGTCATGGCATGGATTTACTAATATTGACAAGCATCAT
ATGTATTTAGATCCAATCAAGGTAACTTTATTAATGCCTGGCTTGAATAAAGACAACACCTTGGACCCCAACGGTATTCC
AGCAACACTGGTATCCAACTACCTGGATTCTAAAGGAATTATTGTTGAAAAAACAGGTCCTTATAATATTCTTGTGTTAT
TTAGTATCGGTATTGACGATACAAAAGCGATGAGCCTAATTCAAGCATTAGATGACTTTAAATCATTGTATGATGCCAAT
GTGCTTGTGAAAGATATTTTACCAAATATCTATGCCCATGCTCCTAAGTTCTATGAAACAATGCGTATTCAAGAATTGGC
AGGAGGAATCCATCGTTTGATATGTAAGCATAATTTACCAGATTTAATGTTCAAAGCATTTGATATATTGCCAAAAATGA
TTATGACGCCTAACAAAGCTTTTAATTTAGAATTGAAAGGAAATATTGATGAATGCTATGTAGAAGATATGGTTGGCAAA
ATCAATGCAAACATGATATTACCTTATCCTCCTGGTGTTCCTTTAATTATGCCTGGTGAGATGATCACTGAAGAAAGTCG
TGCTATTTTAGAGTTTCTGGTCATGCTATGTGAAATAGGAACCCATTATCCTGGTTTTGAAACGGATATTCATGGTGCAT
ATCGTCAAGACGATGGTCGCTACAAAGTAAAAATTATTAATATTTAA

Protein sequence :
MKQILIGYSMYNDHLQNLISALEEKGYKTTAVDGHQEILHAVKNNASIISVILSNDIIDKDLTDKILLLNEDLPIFSLKD
TDDLNENLDFATIGHHVQFVDCNLYTLDEIIHKIERAVEKYFDSITPPLTKALFKYVNEDKYTFCTPGHMGGTAFLRSPI
GSVFYDFFGKNTFKSDISVSVGELGSLLDHSGPHKEAEKYIANVFNADRSYIVTNGTSTANKIVGMYSAPSGSTVLIDRN
CHKSLTHLLMMSDVTPIYLKPTRNAYGLLGGIPEQEFSKSAIEKKLADIDNPNWPVHAVITNSTYDGLFYNTDKIKETLD
VKSIHFDSAWVPYTNFNPIYEGKTGMGGKRVEDKIIYETQSTHKLLAAFSQASMIHIKGQINEETFNEAYMMHTSTSPHY
GIVSSTEVAAAMMKNNTGKQLLQDAITRAVRFRKEIKQRMRESQSWYFDVWQPENISSTECWELKPGESWHGFTNIDKHH
MYLDPIKVTLLMPGLNKDNTLDPNGIPATLVSNYLDSKGIIVEKTGPYNILVLFSIGIDDTKAMSLIQALDDFKSLYDAN
VLVKDILPNIYAHAPKFYETMRIQELAGGIHRLICKHNLPDLMFKAFDILPKMIMTPNKAFNLELKGNIDECYVEDMVGK
INANMILPYPPGVPLIMPGEMITEESRAILEFLVMLCEIGTHYPGFETDIHGAYRQDDGRYKVKIINI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 67
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_719218.1 L-lysine decarboxylase VFG1670 Protein 0.0 67