Gene Information

Name : metB (FRAAL0783)
Accession : YP_711051.1
Strain : Frankia alni ACN14a
Genome accession: NC_008278
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 850433 - 851611 bp
Length : 1179 bp
Strand : -
Note : Evidence 2b : Function of strongly homologous gene; PubMedId : 3307782; Product type e : enzyme

DNA sequence :
ATGAGCACCGACGAGTTCGCCGACGGGTTCGAGACGATCGCGATCCACGCCGGGCAGGATCCCGATCCGGGCACCGGCGC
GGTGGCGCCCCCCCTCCATCTGTCCTCGACCTTCGCCCAGGACGGCGTGGGCGGCCTGCGCGGCGGATTCGAGTACTCCC
GGTCCGGCAACCCGACCCGCGCGGCCCTGGAGACCTGCCTCGCCGCGCTGGAGGGCGGCCGCGTGGGCCTCGCCTTCTCC
GCGGGCATGGCGGCGACCGACACACTGCTGCGGGCGGTGTGCCGCCCCGGCGATCATGTGATCATCCCGGCCGACGCCTA
CGGCGGGACCTACCGGCTGATCGCCCGGGTCCTCGGCGAGTGGGGGGTCGAGCACAGCAGCGTCGACCTCACCGACCTGG
AGGCGACCCGGGCCGCGGTCCGCCCGGGCGTGACCCGGCTGGTGTGGTGCGAGACGCCGACGAACCCGCTGCTGACGATC
GCCGACATCGCCGCGCTCGCGTCGCTCGCCCACGACGCCGGCGCACTGCTCGCCGTGGACAACACGTTCGCCTCGCCCTA
CCTTCAGCAGCCGCTGGCCCTCGGCGCCGACGCCGTGGTCCACTCCACCACGAAGTACCTCGGCGGCCACAGCGACGTCG
TGGGCGGCGCGATCGTGGTCAGCGATCCCGAACTCGGCACGCAGCTGCGATTCCTGCAGAACGCGGCCGGTGCCGTCCCC
GGACCGTTCGACTGCTGGCTCGTCCTGCGCGGCATCAAGACGCTCGCCGTGCGGATGGACCGGCACTGCGCCAACGCCCG
CGGTGTCGCCACCCTGCTGGCGGCGCATCCGGCCGTCTCGACGGTGTACTACCCGGGCCTGCCCGGTCATGCCGGGCACG
GCATCGCCGCCAAACAGATGCGCGACTTCGGCGGGATGGTCTCGCTCACCCTGCGGGACGGCCCGCGGGCCGCGGTCGAA
CTGTGCGGGCGGACCCGGCTGTTCACCCTCGCCGAGTCACTCGGCGGAGTGGAATCCCTGATCGAGCATCCGGCCAGCAT
GACGCATGCGTCGGTCGTAAACTCGCCGCTCGCCGTGCCGGCGGAGCTCGTCCGGCTCTCGGTCGGCATCGAATCGGCCG
ACGACCTCGCGGCCGATCTGCGCCGCGCCCTGGACGGACTTTCGACCCGTTCCGCTTAG

Protein sequence :
MSTDEFADGFETIAIHAGQDPDPGTGAVAPPLHLSSTFAQDGVGGLRGGFEYSRSGNPTRAALETCLAALEGGRVGLAFS
AGMAATDTLLRAVCRPGDHVIIPADAYGGTYRLIARVLGEWGVEHSSVDLTDLEATRAAVRPGVTRLVWCETPTNPLLTI
ADIAALASLAHDAGALLAVDNTFASPYLQQPLALGADAVVHSTTKYLGGHSDVVGGAIVVSDPELGTQLRFLQNAAGAVP
GPFDCWLVLRGIKTLAVRMDRHCANARGVATLLAAHPAVSTVYYPGLPGHAGHGIAAKQMRDFGGMVSLTLRDGPRAAVE
LCGRTRLFTLAESLGGVESLIEHPASMTHASVVNSPLAVPAELVRLSVGIESADDLAADLRRALDGLSTRSA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-67 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-68 45
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-48 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_711051.1 cystathionine gamma-synthase BAC0207 Protein 2e-58 45