Gene Information

Name : thcA (RHA1_ro08917)
Accession : YP_708119.1
Strain :
Genome accession: NC_008269
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase (NAD+)
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 883586 - 885109 bp
Length : 1524 bp
Strand : +
Note : -

DNA sequence :
ATGACCGTGTATGCCCGCCCGGGTTCGCCGGACGCCGTCATGTCCTTCCAATCGCGTTACGACAACTGGATCGGCGGCCA
GTGGGTTGCGCCCGTCAAGGGCCAGTACTTCGAGAATCCGACACCCGTCACCGGACAGCCGTTTTGTGAGGTCGCGCGTT
CGACGTCCGAGGACATCGAACTTGCGCTCGACGCCGCACACGCTGCGGCTCCGGCCTGGGGCAAGACGTCGGTGGCGGAG
CGCGCCATCATCCTGAACAAGATCGCGGACCGCATCGAGGAGAACCTCGAGTCCATCGCGCTCGCCGAGTCCTGGGACAA
CGGCAAGCCGATCCGCGAGACCCTGTACGCCGATATTCCGTTGGCCGTGGATCACTTCCGTTACTTCGCCGGCGCTATCC
GGGCGCAGGAAGGCGCACTGTCGGAGATCGACTCCGACACCGTCGCCTACCACTTCCACGAGCCGCTCGGCGTGGTCGGC
CAGATCATCCCCTGGAACTTCCCGATCCTCATGGCCGTGTGGAAGCTCGCTCCCGCACTCGCCGCGGGTAATGCGGTCGT
TCTCAAGCCCGCCGAGCAGACCCCGGCGTCGATCCTGCACCTGATCTCCGTCATCGGCGACCTGCTGCCCGCCGGTGTGC
TGAACATCGTCAACGGCTTCGGTGTGGAGGCGGGCAAGCCGCTCGCCTCGAGCCCGCGGATCCGGAAGATCGCGTTCACC
GGTGAGACCACCACGGGCCGGCTCATCATGCAGTACGCGTCGCAGAACCTGATCCCGGTCACCCTCGAACTCGGTGGCAA
GAGCCCCAACATCTTCTTCTCCGACGTGCTGTCCTCCAACGACGACTACCAGGACAAGGCGCTCGAGGGCTTCACGATGT
TCGCCCTCAACCAGGGCGAGGTGTGCACCTGCCCGTCGCGTTCGCTGATCCAGGAGGACATCTTCGACGAGTTCCTCGCG
ATGGCGGCCATCCGCACCAAGGCCGTCCGTCAGGGCGACCCGCTCGACACCGACACGATGATCGGCGCGCAGGCCTCGAA
CGATCAGCTCGAGAAGATCCTGTCGTACATCGAGATCGGCAAGGGCGAAGGCGCCAAGGTCGTCACCGGCGGTGAGCGCG
CCGAACTCGGCGGCGACCTGTCCGGCGGCTACTACGTGCAGCCGACGATCTTCACCGGTCAGAACAAGATGCGGATCTTC
CAGGAGGAGATCTTCGGTCCCGTCGTCTCCGTCACGTCGTTCAAGGACTACGACCAGGCCATCGAGATCGCCAACGACAC
GCTGTACGGCCTCGGCGCCGGCGTGTGGTCGCGGGACGGTGGCGTCGCCTACCGCGCCGGTCGCGACATCCAGGCCGGGC
GCGTGTGGACCAACACGTACCACCAGTACCCCGCGCACGCGGCGTTCGGTGGCTACAAGCAGTCCGGCATCGGCCGCGAG
AACCACCTGATGATGCTCGAGCACTACCAGCAGACGAAGAACCTGCTGGTCAGCTACGCCCAGAAGGCTCAGGGCTTCTT
CTGA

Protein sequence :
MTVYARPGSPDAVMSFQSRYDNWIGGQWVAPVKGQYFENPTPVTGQPFCEVARSTSEDIELALDAAHAAAPAWGKTSVAE
RAIILNKIADRIEENLESIALAESWDNGKPIRETLYADIPLAVDHFRYFAGAIRAQEGALSEIDSDTVAYHFHEPLGVVG
QIIPWNFPILMAVWKLAPALAAGNAVVLKPAEQTPASILHLISVIGDLLPAGVLNIVNGFGVEAGKPLASSPRIRKIAFT
GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFSDVLSSNDDYQDKALEGFTMFALNQGEVCTCPSRSLIQEDIFDEFLA
MAAIRTKAVRQGDPLDTDTMIGAQASNDQLEKILSYIEIGKGEGAKVVTGGERAELGGDLSGGYYVQPTIFTGQNKMRIF
QEEIFGPVVSVTSFKDYDQAIEIANDTLYGLGAGVWSRDGGVAYRAGRDIQAGRVWTNTYHQYPAHAAFGGYKQSGIGRE
NHLMMLEHYQQTKNLLVSYAQKAQGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-147 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-154 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-154 62
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-154 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-153 62
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-69 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
thcA YP_708119.1 aldehyde dehydrogenase (NAD+) VFG0082 Protein 2e-147 63