Gene Information

Name : guaA (RHA1_ro06202)
Accession : YP_706137.1
Strain : Rhodococcus jostii RHA1
Genome accession: NC_008268
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 6688017 - 6689588 bp
Length : 1572 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGGCAGATATCGAGCAACAGAGACCGGTCCTCGTCGTCGACTTCGGCGCGCAGTATGCGCAGCTGATCGCCCGGCGGGT
GCGTGAGGCCAAGGTCTATTCCGAGGTGGTTCCGCACACCGCGACCGTCGAGGAGATCGCGGCCAAGAATCCCCTTGCCG
TGGTGCTGTCGGGTGGGCCGTCGAGCGTCTATGCGGACGGTGCGCCGCAGCTCGATCCGGCGCTGTTCGATCTGGACATT
CCCGTGTTCGGCATCTGCTACGGATTCCAGGCCATGGCCGGCGCACTCGGCGGGACGGTGGCACACACCGGCACCCGGGA
GTACGGCCGCACCGACCTCAAGGTGCAGGGCGGTCTGCTGCACGAGGGGCTGCCGGCCAGCCAGCCCGTGTGGATGAGTC
ACGGCGACGCGGTCACCGAGGCCCCGGCGGGCTTCGAGGTGACAGCCACGAGCGAGGGCGCACCCGTCGCCGCGTTCGAG
GACCGGGCCCGCAAGCTCGCGGGTGTGCAGTACCACCCGGAGGTGCTGCACTCGCCGCACGGTCAGCAGGTGCTCAGCCG
GTTCCTCCACGAGATCGCCGGCATTCCTCCCGCATGGACGGCCGCGAACATCGCCGACGCCCTCGTCGAGCAGGTCCGCG
AGCAGGTCGGCGACGGCAAGGCGATCTGCGGGCTCTCCGGCGGTGTCGACTCCGCTGTCGCGGCGGCGCTCGTGCAGCGC
GCCATCGGCGACAACCTGACGTGTGTGTTCGTCGACCACGGTCTGATGCGTGCGGGCGAGCGTGCCCAGGTCGAGCAGGA
TTTCGTTGCCGCGACCGGCGCAAAGCTGATCACGGTCGACGCCGCCGACACCTTCATCGGTGAGCTGGCGGGCGTGTCCG
ACCCGGAGACCAAGCGCAAGATCATCGGCCGCGAGTTCATCCGCAGCTTCGAGGGCGCGGTCAGCGACGTGCTGGGCGAG
AACGCCGCGCACGGCGACACGGTCGAATTCCTCGTGCAGGGCACGCTGTACCCGGACGTCGTGGAATCCGGCGGCGGCAC
CGGCACGGCCAACATCAAGAGCCACCACAACGTCGGCGGACTGCCCGAAGACCTGCAGTTCACGCTCGTGGAACCGCTCC
GCCTGCTGTTCAAGGACGAGGTCCGGGCGGTGGGGCGCGAGCTGGGTCTGCCCGAGGAAATCGTGGGACGCCAGCCGTTC
CCCGGTCCCGGCCTGGGCATCCGCATCATCGGCGAGGTCACGCAGGACCGGCTCGACATCCTGCGTCACGCGGATTCCAT
TGCGCGCGAAGAGCTGACGGCCGCCGGGCTCGACGGTCAGATCTGGCAGTGCCCCGTGGTGCTGCTCGCCGACGTCCGCA
GCGTCGGGGTGCAGGGCGACGGACGCACCTACGGCCACCCGATCGTGCTCCGCCCGGTGTCCAGCGAGGACGCGATGACC
GCGGACTGGACGCGACTGCCCTACGACGTTCTCGAGCGGATCTCCACCCGAATCACCAACGAGGTGCACGACGTCAACCG
TGTCGTGCTGGACATCACGAGCAAGCCTCCGGGCACCATCGAGTGGGAGTGA

Protein sequence :
MADIEQQRPVLVVDFGAQYAQLIARRVREAKVYSEVVPHTATVEEIAAKNPLAVVLSGGPSSVYADGAPQLDPALFDLDI
PVFGICYGFQAMAGALGGTVAHTGTREYGRTDLKVQGGLLHEGLPASQPVWMSHGDAVTEAPAGFEVTATSEGAPVAAFE
DRARKLAGVQYHPEVLHSPHGQQVLSRFLHEIAGIPPAWTAANIADALVEQVREQVGDGKAICGLSGGVDSAVAAALVQR
AIGDNLTCVFVDHGLMRAGERAQVEQDFVAATGAKLITVDAADTFIGELAGVSDPETKRKIIGREFIRSFEGAVSDVLGE
NAAHGDTVEFLVQGTLYPDVVESGGGTGTANIKSHHNVGGLPEDLQFTLVEPLRLLFKDEVRAVGRELGLPEEIVGRQPF
PGPGLGIRIIGEVTQDRLDILRHADSIAREELTAAGLDGQIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMT
ADWTRLPYDVLERISTRITNEVHDVNRVVLDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 80
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-137 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-137 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-137 52