Gene Information

Name : RHA1_ro04793 (RHA1_ro04793)
Accession : YP_704736.1
Strain : Rhodococcus jostii RHA1
Genome accession: NC_008268
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : 2.3.1.-
Position : 5059461 - 5061113 bp
Length : 1653 bp
Strand : -
Note : bifunctional

DNA sequence : 
ATGAGCACGAGCGTTCGCGCTCCCCTGGAGATCACCGTCGGTTACCCCGCCGACCTCGCCGCACGCTACCGTGACGCAGG
GTACTGGACGGACGAGACGTTCCAGCAGTTCCTGGGCGCCCGCGCCGAGCAATTCGGGGACGCGATCGCCGTGACCGGGC
CGGACGCGTCCGGGGTCGACCGTGCCCTCACCTACCGGGAACTGTCCGACCGCGCCGACCGGCTCGCCGCCGGGCTGCAG
TCGTCGGGGGTGCAGCCCGGCGACCGGGTGGTGGTGCAACTGCCGAACATCGTCGAGTACGTCGAGGTGATCTTCGCGGT
CTTCCGGCTCGGCGCACTGCCGGTGTTCGCGCTGCCCGCGCACCGCGCCCAGGAGATCTCCTACTTCTGCAGCTTCACCG
ACGCCGCGGCCTACGTCGTCACCGATACGCACGCCGGATTCGACTACCGCACCCTCGCCCGCGACGTGGTGTCCTCGGCC
GAGAATCCGCCCCGGATCATCGTGGCCGGGGACGCGGAGGAGTTCACGTCACTCGACGAACTCCGGGCGGCGGAACCGAT
GTCGGACGGGCCGGCGGTGGGTCCGGAATCGGTGGCATTCCTGCAGCTCTCGGGCGGAACCACCGGGGTGTCGAAGCTGA
TCCCGCGCACGCACACCGACTACCTGTACTCGGTGCGCGAGTCGGACCGCATCTGCGGCGTCGACGAGAGCACGCGCATG
CTCGTCGTTCTGCCTGCGGCGCACAATTTTCCGATGAGCTCACCGGGCATCCTCGGCGTGCTGCACGCCGGTGGTCGCGT
GGTGCTCGCGCCGGATCCGAGTCCCGACACCGCGTTCGCGCTCATCGAGAAGGAGGGCGTCACGATTGCGTCGCTGGTGC
CGCCGCTCGCGTTGGCGTGGCTGGCCGCCAGTGGTCGCACGGAACGCGACCTCTCGAGCCTCGAGGTGCTACAGGTGGGC
GGTGCCAAGTTCAGCGCCGAGGCCGCGAAGCGGGTCCGTCCCGAACTCGGGTGCACGCTGCAGCAGGTCTTCGGGATGGC
GGAGGGCCTGGTCAACTACACCCGCCTCGACGACCCGGAAGACACGATCGTCACCACCCAGGGCAGACCGATCAGCCCCG
ACGACGAGGTCCGGGTCGTCGACGACCGGGGCGAGCCCGTCCCGAACGGCACGTCCGGTCATCTGCTCACCCGCGGCCCG
TACACCGTCCGCGGGTATTACCAGGCTCCCGAACACAATTCGACGGCGTTCACCGAGGACGGCTTCTACCGCACCGGCGA
CATCGTCCGGCTCACGGACGACGGCTACCTCGTCGTCGAGGGCCGCGCGAAGGATCAGATCAACCGCGGCGGCGAGAAGG
TGGCCGCGGAAGAGGTCGAGAACCATCTGCTCGCACACCCCGCCGTCGCCGACGTCGCGGTGGTGTCGATGCCCGATCCG
TATCTCGGCGAGCGCAGTTGCGCGTTCGTCGTGGTCCAGGGCGAGCAGCCGAAGGCGGTCGAACTCAAGAAGTTCGTCCG
CGGCCGCGGACTCGCCGAGTACAAGGTGCCGGACAAGGTGGTGTTCGTCGACGAGTTCCCGGTCACCGGTGTCGGCAAGA
TCAGCAAGTCCGACCTGCGCCGGGCACTGGAGAAGACGTTCGTGACTTCGTAA

Protein sequence : 
MSTSVRAPLEITVGYPADLAARYRDAGYWTDETFQQFLGARAEQFGDAIAVTGPDASGVDRALTYRELSDRADRLAAGLQ
SSGVQPGDRVVVQLPNIVEYVEVIFAVFRLGALPVFALPAHRAQEISYFCSFTDAAAYVVTDTHAGFDYRTLARDVVSSA
ENPPRIIVAGDAEEFTSLDELRAAEPMSDGPAVGPESVAFLQLSGGTTGVSKLIPRTHTDYLYSVRESDRICGVDESTRM
LVVLPAAHNFPMSSPGILGVLHAGGRVVLAPDPSPDTAFALIEKEGVTIASLVPPLALAWLAASGRTERDLSSLEVLQVG
GAKFSAEAAKRVRPELGCTLQQVFGMAEGLVNYTRLDDPEDTIVTTQGRPISPDDEVRVVDDRGEPVPNGTSGHLLTRGP
YTVRGYYQAPEHNSTAFTEDGFYRTGDIVRLTDDGYLVVEGRAKDQINRGGEKVAAEEVENHLLAHPAVADVAVVSMPDP
YLGERSCAFVVVQGEQPKAVELKKFVRGRGLAEYKVPDKVVFVDEFPVTGVGKISKSDLRRALEKTFVTS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-101 48
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-101 48
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-100 47
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-100 47
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-100 47
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-100 47
ybtE CAA21394.1 - Virulence HPI Protein 3e-100 47
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-100 47
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-100 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RHA1_ro04793 YP_704736.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 3e-121 52
RHA1_ro04793 YP_704736.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 3e-104 48
RHA1_ro04793 YP_704736.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 2e-106 47