Gene Information

Name : leuS (RHA1_ro03622)
Accession : YP_703583.1
Strain : Rhodococcus jostii RHA1
Genome accession: NC_008268
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3825524 - 3828361 bp
Length : 2838 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGACCGAGCACGTGCAGCCCGCCAACCCGTCCGACGCGACCCCGCAGCACCGCTACACCGCGGAGCTCGCCGGCCAGAT
CGAGCAGCGCTGGCAGGACCGGTGGAGCGAGGAGGGCACGTTCAACGCGCCCAACCCGGTCGGTCCCCTCGCCGGCGACG
TTCCCGCGGACAAGTTGTTCGTGCAGGACATGTTTCCGTACCCGTCGGGCACGGGTCTGCACGTGGGCCACCCGCTCGGC
TACATCGCCACCGACGTGTTCGCCCGCTATCACCGCATGCAGGGCCACAACGTGCTGCACACCCTCGGCTACGACGCGTT
CGGTCTGCCTGCCGAGCAGTACGCGGTGCAGACGGGCACGCACCCGCGGACCACCACCGAGGCCAACATCGTCAACATGA
AGCGGCAGCTGCGCCGCCTCGGGCTCGGCCACGACGAACGCCGCACATTCGCGACCACCGACACCGACTTCTATCACTGG
ACGCAGTGGATCTTCCTGCAGATCCACGACGCGTGGTTCGACAAGGAGGCGGGCAAGGCCCGGCGGATCTCGGAGCTCGA
GGCCGAGTTCGTGTCGGGTGCGCGCTCGCTGGAGGACGGACGGGAATGGGCGTCGCTGTCCGTGTCCGAGAAGGAGGCCG
TCCTCGACTCCTATCGCCTCGTCTACCACTCCGATTCGATGGTCAACTGGTGCCCCGGTCTGGGCACGGTACTGGCGAAC
GAAGAGGTGACCGCCGACGGTCGCAGCGACCGCGGCAACTTCCCCGTGTTCCGTAAGCACCTGCAGCAGTGGATGATGCG
CATCACCGCGTACTCGGACCGTCTGGTGGACGACCTGGAGTACCTGGACTGGCCCGAGAAGGTCAAGACCATGCAGCGCA
ACTGGATCGGGCGCTCGCACGGTGCGCAGGTGAAGTTCCAGGCGGACGGTCATGAGATCGAGGTGTTCACGACGCGTCCG
GACACGCTGTTCGGCGCGACGTACGTGACGCTGGCGCCGGAGCACGAACTGGTGGACGACATCGTTGCGGCCGAGTGGCC
CCGGGGTGTGGATTCGCGCTGGACCGGTGGTGCCGCAACTCCCGCCGAAGCGGTTGCGGCGTACCGGAAGTCGATCGCGG
CCAAGTCGGATCTCGAGCGTCAGGAATACAAGGAGAAGACGGGCGTCTTCCTCGGCACCTACGCGGTGAACCCCGTCAAC
GGGCACAAGTTGCCGGTGTTCATCGCCGACTACGTCCTCACCGGCTACGGCACGGGCGCCATCATGGCGGTCCCGGGCCA
CGACCACCGCGACTACGAGTTCGCGACCGAATTCGGTCTCGACATCGTCGAGGTCATCTCCGGCGGCGACCTCACCAAGG
ACGCGTACACCGGCGACGGCACCATCGTGAACTCCGATTTCCTGAACGGCATGAGTGTCGCCGATGCCAAGAAGGCGATC
ACCGAGCGTCTGGAAGCGGACGGCACCGGCAAGGGCACCATCCAGTACAAGCTGCGCGACTGGCTGTTCGCACGCCAGCG
GTACTGGGGCGAGCCGTTCCCGATCGTGTACGACGCCGAGGGCAACGCGCACGCCCTGCCGGAATCGTCTCTGCCCGTCG
AACTCCCGGAGGTCGAGGACTACGCACCCGTGTCGTTCGATCCCGACGACGCGTCCTCGGAGCCCTCTCCCCCGCTGGCG
AAGGCCGTCGACTGGGTCAACGTCGAACTCGACCTCGGCGACGGGCTGCAGACGTACCGCCGCGACACCAACGTGATGCC
GCAGTGGGCCGGCAGCTCCTGGTACCAGCTGCGGTACATCGACCCCACCAACCCGGACGTGTTCTGCGACAAGGAGAACG
AGCGGTACTGGACGGGTCCGCGCCCGGAGATCCACGGACCCAACGATCCCGGCGGCGTCGACCTGTACGTCGGCGGCGTC
GAGCATGCGGTGCTGCACCTGCTGTACTCGCGGTTCTGGCACAAGGTGCTGTTCGACCTCGGCTACGTCAGCTCGAGCGA
GCCGTACCGCCGTCTGTACAACCAGGGCTACATCCAGGCGTACGCGTACACCGATGCGCGCGGCGTGTACGTGCCCGCCG
ACGAGGTGGAGGAGAAGGACGGCAAGTTCTTCCACCAGGGCGTCGAGGTCAACCGCGAGTACGGGAAGATGGGCAAGAGC
CTCAAGAACTCCGTGTCGCCGGACGAGATCTGCGAGGAGTACGGCGCCGACACGCTCCGCGTGTACGAGATGTCGATGGG
CCCGCTGGACACGTCCCGCCCGTGGGCGACCAAGGACGTCGTCGGTGCGCAGCGCTTCCTGCAGCGCGCGTGGCGGGTGG
TGGTCGACGAGGAGTCCGGTGCACTGCGCGTCACCGACGACGCCCCGGCGGAGGACACGCTGCGCGCGCTGAACAAGGCG
ATCGCCGGTGTGAGCGAGGACTACACGGCCCTGCGCGACAACACGGCGGCGGCCAAGCTGATCGAGTACACCAACCACCT
CACCAAGGCGTACCCCGGCGGTGCCCCCCGCTCGGTGGTGGAGCCGCTGGTGCTGATGCTGGCACCGCTGGCCCCGCACC
TCGCGGAGGAGCTGTGGTCGCGGCTCGGGCACGAGAAGTCCCTGGCCCACGGCCCCTTCCCGGTGGCCGAGGAGAAGTGG
CTGGTGGAAGACACCGTCGAGTACCCGATCCAGGTCAACGGCAAGGTCCGGAGCCGCGTGACCGTCGCGGCAGACGCCCC
GCGCGAGGAGATCGAGAAGATCGCGCTGGCCGACGACAAGATCGTGGCGCTCCTCGACGGCCAGGATCCCCGCAAGGTGA
TCGTCGTTCCCGGCAAGATGGTCAACATAGTGCGCTGA

Protein sequence :
MTEHVQPANPSDATPQHRYTAELAGQIEQRWQDRWSEEGTFNAPNPVGPLAGDVPADKLFVQDMFPYPSGTGLHVGHPLG
YIATDVFARYHRMQGHNVLHTLGYDAFGLPAEQYAVQTGTHPRTTTEANIVNMKRQLRRLGLGHDERRTFATTDTDFYHW
TQWIFLQIHDAWFDKEAGKARRISELEAEFVSGARSLEDGREWASLSVSEKEAVLDSYRLVYHSDSMVNWCPGLGTVLAN
EEVTADGRSDRGNFPVFRKHLQQWMMRITAYSDRLVDDLEYLDWPEKVKTMQRNWIGRSHGAQVKFQADGHEIEVFTTRP
DTLFGATYVTLAPEHELVDDIVAAEWPRGVDSRWTGGAATPAEAVAAYRKSIAAKSDLERQEYKEKTGVFLGTYAVNPVN
GHKLPVFIADYVLTGYGTGAIMAVPGHDHRDYEFATEFGLDIVEVISGGDLTKDAYTGDGTIVNSDFLNGMSVADAKKAI
TERLEADGTGKGTIQYKLRDWLFARQRYWGEPFPIVYDAEGNAHALPESSLPVELPEVEDYAPVSFDPDDASSEPSPPLA
KAVDWVNVELDLGDGLQTYRRDTNVMPQWAGSSWYQLRYIDPTNPDVFCDKENERYWTGPRPEIHGPNDPGGVDLYVGGV
EHAVLHLLYSRFWHKVLFDLGYVSSSEPYRRLYNQGYIQAYAYTDARGVYVPADEVEEKDGKFFHQGVEVNREYGKMGKS
LKNSVSPDEICEEYGADTLRVYEMSMGPLDTSRPWATKDVVGAQRFLQRAWRVVVDEESGALRVTDDAPAEDTLRALNKA
IAGVSEDYTALRDNTAAAKLIEYTNHLTKAYPGGAPRSVVEPLVLMLAPLAPHLAEELWSRLGHEKSLAHGPFPVAEEKW
LVEDTVEYPIQVNGKVRSRVTVAADAPREEIEKIALADDKIVALLDGQDPRKVIVVPGKMVNIVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-146 48