Gene Information

Name : pyk3 (RHA1_ro03221)
Accession : YP_703182.1
Strain : Rhodococcus jostii RHA1
Genome accession: NC_008268
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3406271 - 3407782 bp
Length : 1512 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGACCGAGTCGGTCACGCGCACCGCACCGCACCGCAGTGAAGTCGTCAGCGAGTCGGCGAGCACCACACGCCACTTCGA
CAGCCACACTGCTCCACTACGCCACACGAAGATCGTATGCACACTTGGACCTGCTACCGCCACCGGTGACCGTATTCGCG
AACTCGTCGAAAGCGGTATGGACGTGGCGCGGCTGAATTTCAGCCACGGCGAACACGCCGACCACGAGGAGAACTACAAA
CGCGTCCGGGCGGCCTCGGACGCGACGGGGAAGGCGGTCGGTGTCCTCGCCGACCTGCAGGGCCCGAAGATCCGGCTCGG
CCGGTTCGCCGAGGGGCGCACCACGTGGGCCAACGGTGAGGAAGTGCGGATCACCGTCGACGAGGTCGAGGGCACCCACG
ACCGGGTGTCGACCACCTACAAGCAGCTCGCCGAGGACGCCAAGGCCGGTGACCGCCTGCTGGTCGACGACGGCAAGGTC
GGTCTCGTCGTCTCCGGGGTGGACGGCAACGACGTGATCTGCCGGGTCACCGAGGGCGGCCCGGTCAGCAACAACAAGGG
TGTGTCCCTGCCGGGGATGAACGTGTCGGTCCCGGCGCTGTCGGAGAAGGACATCGCCGACCTCGAGTTCGCGCTCGGTC
TCGGTGTCGACTTCATCGCCCTGTCGTTCGTGCGGTCGCCGGCCGACGTGGAACTGGTTCACGCCGTGATGGATCGGGTC
GGTCGCCGGATCCCGGTGATCGCGAAGCTCGAGAAGCCGGAGGCGATCGACAACCTCGAGGCGATCGTGCTGGCGTTCGA
CGCGGTGATGGTCGCCCGTGGTGACCTGGGGGTGGAGTTGCCGCTCGAACAGGTGCCGCTGGTGCAGAAGCGGGCGATCC
AGATCGCCCGGGAGAACGCGAAGCCGGTCATCGTCGCGACGCAGATGCTGGAGTCGATGATCGAGAACTCGCGGCCCACC
CGCGCCGAGGCGTCCGACGTCGCGAACGCGGTCCTCGACGGTGCGGACGCGGTGATGCTGTCGGGTGAGACGTCGGTGGG
CAAGTACGTGATGGAGACGGTGCGCACGATGGCGCGGATCGTCGAGGCGGTGGAGAACGAGTCCACTCAGGTGCCGCCGC
TCACGCACGTGCCGCGGACCAAGCGCGGTGTCATCTCCTATGCGGCCCGCGACATCGGGGAGCGGCTGGATGCGAAGGCG
CTGGTCGCGTTCACCCAGTCCGGGGACACGGTGCGCCGGTTGGCGCGGCTGCACACGCCGTTGCCGTTGCTGGCGTTCAC
CCCGCTGCCGGAGGTGCGCAGCCAGTTGTCGCTGACGTGGGGTACCGAGACGTTCATCGTCGATCCGGTCGAGAGCACCG
ACGCGATGGTGCGGCAGGTCGACCACGCGCTGCTCGGGTTGGGCCGGTACCAGAAGGGGGAACTGGTGGTCATCGTGGCC
GGGTCGCCGCCCGGCACCGTCGGCTCGACCAACCTGATCCACGTCCACAGAATCGGCGAAGAGGACCACTGA

Protein sequence :
MTESVTRTAPHRSEVVSESASTTRHFDSHTAPLRHTKIVCTLGPATATGDRIRELVESGMDVARLNFSHGEHADHEENYK
RVRAASDATGKAVGVLADLQGPKIRLGRFAEGRTTWANGEEVRITVDEVEGTHDRVSTTYKQLAEDAKAGDRLLVDDGKV
GLVVSGVDGNDVICRVTEGGPVSNNKGVSLPGMNVSVPALSEKDIADLEFALGLGVDFIALSFVRSPADVELVHAVMDRV
GRRIPVIAKLEKPEAIDNLEAIVLAFDAVMVARGDLGVELPLEQVPLVQKRAIQIARENAKPVIVATQMLESMIENSRPT
RAEASDVANAVLDGADAVMLSGETSVGKYVMETVRTMARIVEAVENESTQVPPLTHVPRTKRGVISYAARDIGERLDAKA
LVAFTQSGDTVRRLARLHTPLPLLAFTPLPEVRSQLSLTWGTETFIVDPVESTDAMVRQVDHALLGLGRYQKGELVVIVA
GSPPGTVGSTNLIHVHRIGEEDH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-66 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-66 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-66 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk3 YP_703182.1 pyruvate kinase VFG0479 Protein 5e-67 41