Gene Information

Name : thiC (RHA1_ro02182)
Accession : YP_702147.1
Strain : Rhodococcus jostii RHA1
Genome accession: NC_008268
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2292377 - 2294023 bp
Length : 1647 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAGCACAAACGTATCTACAGCCACGTCCGTCACCACGGGACCGATCGAGGGCAGCACCAAGCAGTACCTGCTGTCGGC
CGACGACGTCCGGGTGCCGGTCCGGCGCGTCCACCTCACCAACGGTGAGCACCTCGACGTGTACGACACGTCGGGTCCGT
ACACCGACGCGGACGCCACGATCGACCTGGAAGCGGGACTGCCGCATCTGCGCGCACCGTGGATCGCCGACCGGGAGGGC
ACCCAGCTCGACGCCGCCCGCGCCGGCGTCGTCACCCCCGAGATGCAGTATTGCGCTGCACGCGAGGGTGTTTCACCCGA
GACGGTGCGCACCGAGGTCGCGGCGGGGCGCGCCGTGATCCCTGCCAACCGCTGCCATCCCGAACTCGAGCCGATGATCA
TCGGCAAGGCGTTCGCGGTGAAGATCAACGCGAACATCGGCAACAGCGCGGTCACGTCGTCGATCGCGGAAGAGGTCGAG
AAGATGGTGTGGGCGACGCGGTGGGGCGCAGACACCATCATGGACCTGTCCACCGGAAAGAACATCCACGAGACCCGGGA
ATGGATCCTGCGCAATTCGCCCGTGCCCGTGGGAACCGTGCCGATCTACCAGGCGCTCGAAAAGGTCGGCGGCGACCCGA
CCGCGCTCACCTGGGAGATCTACCGCGACACCGTGATCGAACAGTGCGAGCAGGGCGTCGACTACATGACGGTCCACGCC
GGTGTACTGCTTCGTTACATCCCGCTGACCGCACGCCGGGTCACCGGCATCGTCTCCCGCGGTGGGTCGATCATGGCCGC
CTGGTGTCTGGCCCATCACCGGGAATCGTTCCTGTACAACCACTTCGACGAACTGTGTGAGATCCTCCACCGCTACGACG
TCACGTTCTCGCTCGGTGACGGCCTGCGCCCCGGCTCCATCGCGGACGCCAACGACGAAGCCCAGTTCGCGGAACTGCGC
ACCCTCGGCGAGCTCACGCGGATCGCGAAATCCCATGGGGTGCAGGTGATGATCGAAGGTCCCGGGCACGTCCCGATGCA
CAAGATCGTGGAGAACGTGCGCCTCGAGGAGGAGTTGTGCGAGGAGGCGCCGTTCTACACGCTCGGGCCGCTCGCCACCG
ACATCGCGCCGGCGTACGACCACATCACGTCCGCGATCGGCGCGGCGATGATCGCGCAGGCCGGCACCGCGATGCTCTGC
TACGTGACCCCCAAGGAACACCTGGGACTGCCGAATCGGGACGACGTCAAGACCGGGGTCATCACGTACAAGATCGCGGC
GCACGCCGCGGACCTCGCGAAGCAGCATCCGCGGGCGCAGGAGCGGGACGACGCGCTGTCGAAGGCGCGGTTCGAATTCC
GCTGGCACGACCAGTTCGCGCTGTCCCTCGACCCGGATACCGCGCGGGAGTTCCACGACGAGACGCTGCCCGCCGAGCCG
GCGAAGACGGCCCACTTCTGCTCGATGTGCGGCCCGAAGTTCTGTTCGATGCGGATCTCCGCCGACGTGCGCGAGTACGC
ACAGCAACATGGACTCGATTCGGTAGAAGCCATCGAGGCGGGCATGGCCGAGAAGTCGAGCGAGTTCGTCGACGCAGGTG
GTCGCGTGTATCTGCCCGTCGAATCCGTCACCTCAGAGAATCGGTAA

Protein sequence :
MSTNVSTATSVTTGPIEGSTKQYLLSADDVRVPVRRVHLTNGEHLDVYDTSGPYTDADATIDLEAGLPHLRAPWIADREG
TQLDAARAGVVTPEMQYCAAREGVSPETVRTEVAAGRAVIPANRCHPELEPMIIGKAFAVKINANIGNSAVTSSIAEEVE
KMVWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVGGDPTALTWEIYRDTVIEQCEQGVDYMTVHA
GVLLRYIPLTARRVTGIVSRGGSIMAAWCLAHHRESFLYNHFDELCEILHRYDVTFSLGDGLRPGSIADANDEAQFAELR
TLGELTRIAKSHGVQVMIEGPGHVPMHKIVENVRLEEELCEEAPFYTLGPLATDIAPAYDHITSAIGAAMIAQAGTAMLC
YVTPKEHLGLPNRDDVKTGVITYKIAAHAADLAKQHPRAQERDDALSKARFEFRWHDQFALSLDPDTAREFHDETLPAEP
AKTAHFCSMCGPKFCSMRISADVREYAQQHGLDSVEAIEAGMAEKSSEFVDAGGRVYLPVESVTSENR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 1e-158 67
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 7e-164 62
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 7e-164 62