Gene Information

Name : hemC (RHA1_ro02052)
Accession : YP_702017.1
Strain : Rhodococcus jostii RHA1
Genome accession: NC_008268
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2165497 - 2166462 bp
Length : 966 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAGCGCCGTCGGCACCCGTACGCTGCGGATCGGAACCCGTGGGAGTGAGCTCGCGACCACCCAGGCCGGGACCGTGCG
CGACGCACTGATCTCGGCCGGACACGACGCCGAGCTCGTCATCATCAAGACCAAGGGCGACCAGTCCATGGAATCGGTGG
AGAAGATCGGCGTCGGCGTCTTCACCGCCGAACTCCGGGAAGCGCTCGCCGACGGCCGCGTCGACGTGGCCGTCCACTCC
TACAAGGACCTGCCGACCGCCCCCGACGAACGGTTCACCATCGCCGCCATTCCGCCGCGCGAGGATCCCCGCGACGCGCT
CGTGGCCCGCGACGGACTGGTCCTCGGTGAACTGCCCGCCGGTTCGAAGGTCGGCACGTCCGCACCGCGGCGCACGTCGC
AGCTCCGGGCGCTGGGCCTCGGCCTCGACATCCGTCCGCTGCGCGGCAACCTGCAGCGGCGCCTCGGCAAGGTCGAGTCC
GGCGAACTCGACGCCGTCGTCCTGGCCCGCGCGGGCCTGGCGCGGATCGGACGTCTGGACCTGATCACCGAGTCCATCGA
ACCGGTCCAGATGCTGCCCGCACCCGCACAGGGCGCGCTCGCCGTCGAATGCCTGTCCGCGAACACGGCACTCGTCGCGA
TCCTGTCGGAGCTCGACGACCCGAACAGCCGCGCCGCCGTCACCGCGGAACGCGCACTGCTCGCCGAGCTCGAGGCCGGC
TGCACCGCGCCCGTCGGCGCCATCGCCGAGGTCGTCGAATCACTCGACGACGACGGCCGCATCTTCGACGAACTGTCCGT
CCGGGGCTGCGCCGCAGCCATCGACGGTTCCGACGTCATACGCACGGGGGCCGTGGGCTCCCCGGAGAACGCCGAAGAAC
TCGGCCGCTCCGTCGCGCGTGAGCTTCTCGAGCTCGGTGCGCGGGAGCTGATGAATGTCACCGAGGCCGGTGATGCCGAT
GTTTGA

Protein sequence :
MSAVGTRTLRIGTRGSELATTQAGTVRDALISAGHDAELVIIKTKGDQSMESVEKIGVGVFTAELREALADGRVDVAVHS
YKDLPTAPDERFTIAAIPPREDPRDALVARDGLVLGELPAGSKVGTSAPRRTSQLRALGLGLDIRPLRGNLQRRLGKVES
GELDAVVLARAGLARIGRLDLITESIEPVQMLPAPAQGALAVECLSANTALVAILSELDDPNSRAAVTAERALLAELEAG
CTAPVGAIAEVVESLDDDGRIFDELSVRGCAAAIDGSDVIRTGAVGSPENAEELGRSVARELLELGARELMNVTEAGDAD
V

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 7e-33 41
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 7e-33 41