Gene Information

Name : pyk1 (RHA1_ro01007)
Accession : YP_700992.1
Strain : Rhodococcus jostii RHA1
Genome accession: NC_008268
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1069809 - 1071227 bp
Length : 1419 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence : 
GTGAACCGACGCACGAAGATCGTATGCACACTTGGACCTGCTACCGCCACCGGTGACCGTATTCGCGAACTCGTCGAAAG
CGGTATGGACGTGGCGCGGCTGAATTTCAGCCACGGCGAACACGCCGACCACGAGGAGAACTACAAACGCGTCCGGGCGG
CCTCGGACGCGACGGGGAAGGCGGTCGGTGTCCTCGCCGACCTGCAGGGCCCGAAGATCCGGCTCGGCCGGTTCGCCGAG
GGGCGCACCACGTGGGCCAACGGTGAGGAAGTGCGGATCACCGTCGACGAGGTCGAGGGCACCCACGACCGGGTGTCGAC
CACCTACAAGCAGCTCGCCGAGGACGCCAAGGCCGGTGACCGCCTGCTGGTCGACGACGGCAAGGTCGGTCTCGTCGTCT
CCGGGGTGGACGGCAACGACGTGATCTGCCGGGTCACCGAGGGCGGCCCGGTCAGCAACAACAAGGGTGTGTCCCTGCCG
GGGATGAACGTGTCGGTCCCGGCGCTGTCGGAGAAGGACATCGCCGACCTCGAGTTCGCGCTCGGTCTCGGTGTCGACTT
CATCGCCCTGTCGTTCGTGCGGTCGCCGGCCGATGTGGAACTGGTTCACGCCGTGATGGATCGGGTCGGTCGCCGGATCC
CGGTGATCGCGAAGCTCGAGAAGCCGGAGGCGATCGACAACCTCGAGGCGATCGTGCTGGCGTTCGACGCGGTGATGGTC
GCCCGTGGTGATCTGGGGGTGGAGTTGCCGCTCGAGCAGGTGCCGCTGGTGCAGAAGCGGGCGATCCAGATCGCCCGGGA
GAACGCGAAGCCGGTCATCGTCGCGACGCAGATGCTGGAGTCGATGATCGAGAACTCGCGGCCCACCCGCGCCGAGGCGT
CCGACGTCGCGAACGCGGTCCTCGACGGTGCGGACGCGGTGATGCTGTCGGGTGAGACGTCGGTGGGCAAGTACGTGATG
GAGACGGTGCGCACGATGGCGCGGATCGTCGAGGCGGTGGAGAACGAGTCCACTCAGGTGCCGCCGCTCACGCACGTGCC
GCGGACCAAGCGCGGTGTCATCTCCTATGCGGCCCGCGACATCGGGGAGCGGCTGGATGCGAAGGCGCTGGTCGCGTTCA
CCCAGTCCGGGGACACGGTGCGCCGGTTGGCGCGGCTGCACACGCCGTTGCCGTTGCTGGCGTTCACCCCGCTGCCGGAG
GTGCGCAGCCAGTTGTCGCTGACGTGGGGTACCGAGACGTTCATCGTCGATCCGGTCGAGAGCACCGACGCGATGGTGCG
GCAGGTCGACCACGCGCTGCTCGGGTTGGGCCGGTACCAGAAGGGGGAACTGGTGGTCATCGTGGCCGGGTCGCCGCCCG
GCACCGTTGGCTCGACCAACCTGATCCACGTCCACAGAATCGGCGAAGAGGACCACTAG

Protein sequence : 
MNRRTKIVCTLGPATATGDRIRELVESGMDVARLNFSHGEHADHEENYKRVRAASDATGKAVGVLADLQGPKIRLGRFAE
GRTTWANGEEVRITVDEVEGTHDRVSTTYKQLAEDAKAGDRLLVDDGKVGLVVSGVDGNDVICRVTEGGPVSNNKGVSLP
GMNVSVPALSEKDIADLEFALGLGVDFIALSFVRSPADVELVHAVMDRVGRRIPVIAKLEKPEAIDNLEAIVLAFDAVMV
ARGDLGVELPLEQVPLVQKRAIQIARENAKPVIVATQMLESMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKYVM
ETVRTMARIVEAVENESTQVPPLTHVPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTPLPE
VRSQLSLTWGTETFIVDPVESTDAMVRQVDHALLGLGRYQKGELVVIVAGSPPGTVGSTNLIHVHRIGEEDH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-66 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-66 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-66 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk1 YP_700992.1 pyruvate kinase VFG0479 Protein 5e-67 41