Gene Information

Name : leuS (CPR_0645)
Accession : YP_697972.1
Strain : Clostridium perfringens SM101
Genome accession: NC_008262
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 766652 - 769102 bp
Length : 2451 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGGTAACTATAGTACTGCCATAGATAAGAAATGGCAAGATAAATGGGCTGAATCAGGCCTTTATAAATTTGATCCAAA
TAAAGAAGTAGAGAAACTTTACGTTTTAGAAATGTTCTCATACCCTTCAGGTAGCCAATTACATGCAGGTCACTGGTTTA
ACTATGGACCAGTTGATTCATGGGCTAGATTTAAAAGAATGCAAGGATATAATGTATTCCAACCAATGGGATTTGATGCT
TTCGGTTTACCTGCTGAAAACTTTGCTATAAAAACAGGAATACATCCTCAAGATTCTACAATAAAAAATATAGCTAAAAT
GGAAGAACAATTAAAAGCTATGGGAGCTATGTTTAACTGGGAAAACGAAGTTGTAACTTGCTCACCTGAATATTATAAAT
GGACTCAATGGCTATTCCTAAAATTATACGAGAAAGGATTAGCTTATAGAAAAAAAGCTCCTGTAAACTGGTGTCCATCA
TGCCAAACAGTTCTTGCTAACGAGCAAGTAGTTGATGGAGCTTGTGAAAGATGTTCAACAGAAGTTACTAAAAAAGATCT
TACTCAATGGTTCTTTAAAATAACTGATTATGCTGATGAATTATTAGATAAATTAGATGGTTTAGATTGGCCAGAAAAAA
CAGTTTCTATGCAAAAACACTGGATAGGAAGATCAACTGGTTCTCAAGTTAACTTTAAAGTTAAAGATAGCGATTTAAAC
TTTGATGTATTCACAACAAGAGTTGATACTTTATGCGGAGTCAGCTATGTTGTTTTAGCTCCTGAAAATCCATTAGTAGA
CGAAATAGTTTCAGCTGAACAAAAAGAAGCTGTTGAAAATTATAAAGAAGAAGCTAAAAAACAATCTGATATAGAAAGAC
AATCTATTTCAAGAGAAAAAACTGGTGTATTCACTGGTGCATATGCTATTCATCCATTAACAGGCAAAGAAGTTCCTATA
TGGGTTGGAGACTACGTTCTAGCAACTTACGGAACTGGAGCTGTTATGGCTGTTCCTGCTCATGATGAAAGAGATTTTGC
TTTTGCTGAAAAATTCAACCTTCCAATAAATAGAGTTATAGAAGCTAAAGATGGTAGTGAAACTAACCTTCCATTCTGCG
AGCACGGTATATTAGTTAACTCAGGTGAATTTGATGGATTAACTACAGATGAGGCTAAAGAAAAAATAGTTGAAAAACTA
GCTTCAATGGGCCTTGGAGAAAAGAAAGTTAACTTTAGATTAAGAGACTGGTTAGTTTCAAGACAAAGATACTGGGGAGC
TCCAATTCCTGTAGTTTACTGTGAAGAATGTGGTATAGTTCCTGTACCTGAAAGTCAATTACCAGTTGAATTACCATATG
ATGTTGAATTTGCTCCAGATGGAAAATCTCCACTAGCTAAGAGCGAAGCATTTGTTAACACAACTTGCCCTCACTGTGGA
AAACCAGCTAAGAGAGAAACTGATACTTTAGATACTTTCGTATGTTCATCATGGTATTACTTAAGATATCCTGATAATAA
AAATACTGAGGCTCCATTTAATCCTGAATTAATCAACAAAATGTTACCAGTTGATAAATACGTTGGTGGACCTGAACATG
CTTGTATGCATCTTCTTTACGCAAGATTCATAACTAAAGCCCTAAGAGATATGGGATACCTAAACTTTGATGAACCATTT
ACTTCATTAACTCACCAAGGATTAATCTTAGGACCAGATGGATTAAAAATGAGTAAATCAAAAGGAAACACAATATCTCC
TGATGATTATATAAAAGAATATGGTGCAGATGTATTTAGAATGTACCTAATGTTTGGTTTTGCTTACACTGAAGGTGGAG
CTTGGAGTGATGATGGAATCAAATCTGTAAATAGATTCGTTGAAAGAATTGAAAGAATTATAGATACTGCTAGAGAAGCA
ATCTCAAAAGGTGAAAATAATAAAACTACAATGGATAAGGCTGAAAAAGAGCTTAACTATTGGAGACATAATACTATAAA
ATCTGTTACAGATGATACAGATAAACTTCAATTTAATACAGCAATAGCTAGAATGATGGAATTCATAAATGCTCTATCTA
AATATACTCAAGAGAAAGAAATGAATCTTGATTTCTTAAAAGATGTAGTTTCTGATTATTTAAGATTATTAGCACCATTT
GCACCTCACTTCAGTGAAGAACAATGGAACTTACTTGGAAATTCATACTCAATCTTCAATGAAGCATGGCCAAAATTTGA
CCCTAAAGCTTTAGTTAAAGATGAAGTTGAAATAGCTATACAAGTTAACGGAAAAATCAAAAACAAAATAATGGTTTCTT
CTGATTTAGATGAAGAAGGAATAAAAGCCGCTGCTTTAGCTGATGAGAAAATCATAGCTTCAACAGAAGGAAAAACAGTT
GTAAAAGTAATAGTTATAAAAGGTAGACTTGTAAATATAGTTGTTAAATAA

Protein sequence :
MGNYSTAIDKKWQDKWAESGLYKFDPNKEVEKLYVLEMFSYPSGSQLHAGHWFNYGPVDSWARFKRMQGYNVFQPMGFDA
FGLPAENFAIKTGIHPQDSTIKNIAKMEEQLKAMGAMFNWENEVVTCSPEYYKWTQWLFLKLYEKGLAYRKKAPVNWCPS
CQTVLANEQVVDGACERCSTEVTKKDLTQWFFKITDYADELLDKLDGLDWPEKTVSMQKHWIGRSTGSQVNFKVKDSDLN
FDVFTTRVDTLCGVSYVVLAPENPLVDEIVSAEQKEAVENYKEEAKKQSDIERQSISREKTGVFTGAYAIHPLTGKEVPI
WVGDYVLATYGTGAVMAVPAHDERDFAFAEKFNLPINRVIEAKDGSETNLPFCEHGILVNSGEFDGLTTDEAKEKIVEKL
ASMGLGEKKVNFRLRDWLVSRQRYWGAPIPVVYCEECGIVPVPESQLPVELPYDVEFAPDGKSPLAKSEAFVNTTCPHCG
KPAKRETDTLDTFVCSSWYYLRYPDNKNTEAPFNPELINKMLPVDKYVGGPEHACMHLLYARFITKALRDMGYLNFDEPF
TSLTHQGLILGPDGLKMSKSKGNTISPDDYIKEYGADVFRMYLMFGFAYTEGGAWSDDGIKSVNRFVERIERIIDTAREA
ISKGENNKTTMDKAEKELNYWRHNTIKSVTDDTDKLQFNTAIARMMEFINALSKYTQEKEMNLDFLKDVVSDYLRLLAPF
APHFSEEQWNLLGNSYSIFNEAWPKFDPKALVKDEVEIAIQVNGKIKNKIMVSSDLDEEGIKAAALADEKIIASTEGKTV
VKVIVIKGRLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-176 47