Gene Information

Name : pyk (CPR_0342)
Accession : YP_697671.1
Strain : Clostridium perfringens SM101
Genome accession: NC_008262
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 414114 - 415517 bp
Length : 1404 bp
Strand : +
Note : identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064

DNA sequence :
ATGAGAAGAACAAAATTAGTATGCACTATCGGACCAGCTAGTGAAAACGAAGAAATCTTAACAAAAATAATCGAAGCAGG
TATGAACGCTTCAAGACACAATTTCTCACATGGTGACCATGAAGAACATAAAGGAAGAATGGTTAAAGTAAGAGAAATAT
CAAAAAAATTAGGTAAAGAAGTAGCTATCTTATTAGATACTAAAGGACCTGAAATAAGAACTGGAAAATTCGAGCCAAGC
AAAGTTGAATTAACTGCTGGAACTGAATTTACTATATATGCTGGAGCAGAAGATATAATAGGAGACACTACTAAGTGTTC
AGTTACATATGCTGGATTAGCTAAAGACGTTAAAGCTGGAGATACTATCTTAATAGACGACGGTTTAGTTGGATTAGAAG
TTGTATCTGTAGAAGGAAACGCTGTTAAATGTGTAGTAAGAAACACTGGATTAGTTGGAACTCACAAAGGAGTTAACGTT
CCTGGAGTATCAATAAAATTACCAGCTATGACTGATAAAGATAGAGCTGACTTAATATTTGGTTGTGAAATGGGCGTTAA
CATGGTTGCTGCTTCATTCATAAGAAAAGCAGAAGACGTTAAAGCTATAAGAGAAGTATTAGTTGCTAACGGTGGAGCTG
ATATACAAATATTCTCAAAAATCGAAAACCAAGAAGGTGTTGATAACATAGATGCTATCATCGAAGCTTCAGACGGTATC
ATGGTAGCTAGAGGAGACCTTGGTGTTGAAATACCAATGGAAGACGTTCCTTCAGTTCAAAAAATGATCATCGAAAAATG
TAACAATGCTGGAAAACCAGTTATAACTGCTACTCAAATGTTAGACTCAATGATGAGAAACCCAAGACCAACAAGAGCTG
AGGTTTCAGACGTAACTAACGCTATCTTAGATGGTACTGATGCTATCATGTTAAGTGGTGAGTCAGCTAACGGAAGCTGG
CCAGTAGAAGCTGTTGAAACTATGGTTAAAATAGCTACTAAATCAGAAGAAATGTTAAGCTACGAATTAGCTTCATCAAA
AGCTAAAAAACACATACCAGCTGTACCAGGAGTTATCTCAAGAGCTGCTTGTAACGCTGCACACGAGTTAAAATCAGCTG
CTATAGTTTCATTAACTCAATCAGGAGCTACTGCTAAGAGAATATCTCAATGCAGACCAGATGCACCAATCGTTACTGTA
ACTCCAAATGAAAGAGTTGCTAAGAAAGTTGCTTTATGCTTCGGAGTTTACCCAGTTGTTGCTGAAAATGCTACAATGGA
AAACGCTGTTGAAATAGCTAAAAATGCTGGATTCGTTAAAGCTAATGACACTGCTGTAGTTGTTGCAGGTGTACCAGCTA
ACGAAGGAAACACTAACATAGTAAAAGTTGAAGTTGTAAAATAA

Protein sequence :
MRRTKLVCTIGPASENEEILTKIIEAGMNASRHNFSHGDHEEHKGRMVKVREISKKLGKEVAILLDTKGPEIRTGKFEPS
KVELTAGTEFTIYAGAEDIIGDTTKCSVTYAGLAKDVKAGDTILIDDGLVGLEVVSVEGNAVKCVVRNTGLVGTHKGVNV
PGVSIKLPAMTDKDRADLIFGCEMGVNMVAASFIRKAEDVKAIREVLVANGGADIQIFSKIENQEGVDNIDAIIEASDGI
MVARGDLGVEIPMEDVPSVQKMIIEKCNNAGKPVITATQMLDSMMRNPRPTRAEVSDVTNAILDGTDAIMLSGESANGSW
PVEAVETMVKIATKSEEMLSYELASSKAKKHIPAVPGVISRAACNAAHELKSAAIVSLTQSGATAKRISQCRPDAPIVTV
TPNERVAKKVALCFGVYPVVAENATMENAVEIAKNAGFVKANDTAVVVAGVPANEGNTNIVKVEVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-100 52
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-100 51
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-99 51
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-100 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_697671.1 pyruvate kinase VFG0479 Protein 2e-100 51