Gene Information

Name : pyk (CPR_2116)
Accession : YP_699425.1
Strain : Clostridium perfringens SM101
Genome accession: NC_008262
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2343775 - 2345199 bp
Length : 1425 bp
Strand : +
Note : identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064

DNA sequence :
ATGCAAAAAACAAAAATGATATTTACAATCGGTCCTTCAAGTGATTCAGAAGAAATTCTAAGAGAATTCATAAGAATTGG
TATGAATGCAGCTAGATTAAACTTCTCACATGGAGACCATGCAAGTCATAAAGAAAAGATAGAACTTATTAAAAGACTTA
GAAAAGAAGAAAAATCAGCTACAGCTATCTTATTAGACATTAAGGGTCCTAAAATAAGAACACATAATTTTAAAAATGGC
GAAGCTGAATTAAAAAATGGTGATGAATTCACATTCTCTTGCGGAGATGAAATATTAGGTGATAACACTAAATGTTCAAT
CTCTTATAAAGAACTATATGAAGACATAAAACCTGGTGGATCAATACTTGTTGATGATGGACTTTTAGAATTTAAAGTAA
AGGAAGTCCGTAGAACTGATATAATATGTGAAGTTATTGAAGGAGGTACTATAAAAGACCATAAAGGTGTAAATGTACCT
AATGTACCAATCAAACTCCCTGCAGTAACTGAAAAGGATAGATCTGACTTAATATTTGGTTGCGAAATGGAAGTAGACTT
TGTAGCAGCTTCTTTCATAAGAAAACCTGAGGATGTACTTGAAGTTAGAGAAATTCTAGACTCTCATGGTGGAAAAGATA
TAAAAATAATATCAAAAATAGAAAGCCAAGAAGGTGTAGACAACATAAAAGAAATAATTAAGGTTACTGATGGTGTAATG
GTTGCTAGAGGTGATATGGGAGTAGAAATTCCTATAGAAAATGTACCTATAATTCAAAAAAATATAATTAAGAAATGTAA
TCAAGCAGGAAAAATAGTTATAACTGCAACTCAAATGTTAGATTCTATGATAAGAAATCCAAGACCTACTAGAGCTGAAG
CTTCTGACGTATGTAATGCCATATTTGATGGTACAGATGCCATAATGCTTAGTGGAGAAAGTGCTTCTGGTAGCTTCCCT
ATAGAGGCAGCAATGACAATGTCTAGAATAGCAAAAAAAGCAGAAGCTAACTTAGACTATAATTATCTTTTAAGAAGATT
AAAAGATCCAAATCCAAATCCAGATGCCTTTGCAGATGCCATAAGTTATTCAGCATCAAAAACAGCTAGCAAATTCCCTA
CAAAAGCTATAGTAGCAGCCACTCAGACTGGTTCAACTGCTAAGATATTATCAAAATATAAACCTAGCTGTCCAATAATA
GCTATTACTCCATATGAAAAAGTTAGAAGAAGCTTAGCTTTAAACTTTGGAATAATTTCTAAGAAATGTGCTTATTTTAA
TAGCACAGATGAAATTATAGAGGAAGCTAGAAAAGTAGCTAAGGAATTCCAAATAGCTGAAACTGGCGATAATATAATGG
TAGCTGCTGGATTCCCAACATCAATAACTGGTGGAACAAACATGCTAAAAATTGAAAAAATATAA

Protein sequence :
MQKTKMIFTIGPSSDSEEILREFIRIGMNAARLNFSHGDHASHKEKIELIKRLRKEEKSATAILLDIKGPKIRTHNFKNG
EAELKNGDEFTFSCGDEILGDNTKCSISYKELYEDIKPGGSILVDDGLLEFKVKEVRRTDIICEVIEGGTIKDHKGVNVP
NVPIKLPAVTEKDRSDLIFGCEMEVDFVAASFIRKPEDVLEVREILDSHGGKDIKIISKIESQEGVDNIKEIIKVTDGVM
VARGDMGVEIPIENVPIIQKNIIKKCNQAGKIVITATQMLDSMIRNPRPTRAEASDVCNAIFDGTDAIMLSGESASGSFP
IEAAMTMSRIAKKAEANLDYNYLLRRLKDPNPNPDAFADAISYSASKTASKFPTKAIVAATQTGSTAKILSKYKPSCPII
AITPYEKVRRSLALNFGIISKKCAYFNSTDEIIEEARKVAKEFQIAETGDNIMVAAGFPTSITGGTNMLKIEKI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-91 48
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-91 48
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-91 48
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-90 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_699425.1 pyruvate kinase VFG0479 Protein 2e-91 48