Gene Information

Name : polA (CPR_1962)
Accession : YP_699271.1
Strain : Clostridium perfringens SM101
Genome accession: NC_008262
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 2166242 - 2168842 bp
Length : 2601 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGAAAAGATTATTGATATTAGACGGGAACAGTCTTTTAAATAGAGCCTTTTATGCTGTGCCTTTGCTTAGCAATAGTGA
AGGAACTCATACAAATGCTATTTATGGTTTTACAAATATGCTTTTTAAGATGAGAGAGGATATAAAACCTGATTATATAG
TTTGTACTTTTGATAAAAAAGCACCAACTTTTAGACATTTAGAGTATGGGGATTATAAGGCTGGAAGAAAGAAAATGCCT
CCTGAGTTAGCAGAGCAGTTTCCTATTGTTAAGGAAATGCTAAAGTTATTTTCAATAACAACTTACGAATTAGATGGATT
CGAAGCAGATGATATTATAGGAAGTTTAGCTAAGGTGGCTGAAGGTGAAGGAATCGAAGTTTATATTATTACTGGAGATA
AGGATGCTCTTCAACTAGCAGCTAAGGATATAAACGTATGTATAACTAAGAAGGGTGTTTCTGAAATAGAAGTTTATAAC
TATGATAGAATGGTTGAAGAATATGGAGTTACTCCTACTCAGTTCATAGATGTTAAAGGACTTATGGGAGATAAATCTGA
TAATATTCCAGGGGTACCAGGAGTAGGAGAAAAAACAGCCTTTAAATTAATAAAAGAGTATGGTTCAGTAGAGGCAGTTT
TAGAAAATATAGATAACATAAGTGGTAAAAAGTTAAAAGAAAATTTAACTGAGTACAGCGAACAGGCTATATTCTCTAAA
AAGTTAGCTACTATTATGACTAATGTTCCTATAGATTTTGATTTAGATGAGATTAAATCAAAGGATGATTATAATAAAGA
TCAGTTAAAAGCTTTATTTACAAAGCTTCAAATGAAATCTATATTAGATAAATTATCAAATGGGGAAGAAGAAGAGCCAG
AAATAGAAGTTAAAATAACTAATATAGAAAATAATAAAAAATTAGAAGATTTATTTAATAATATAAACGAAGAAGTATAT
ATTAATTTTACTTATTTAAATAAAGAAAAGTATTCTACTATAGAGATTGATAAAATATTTATTAATTATGATGAGAAAAA
TTATTTAATTAACTTTAAAGAGTTAGCACAAGAAGAGGAGAATATTAAAGCCCTTAAAGAATTTTTTGAGAATGAAGATA
TATTAAAAAATGGCTATAGTATAAAAAATGCCTTAACAGCATTAAAAAAATTAGGGATAGAATTTAAGGGATTAGCCTTT
GATTGTGAATTAGCAGCATATTTAATAGATTCATCTAAGGGAGAATATACTCTTTTATCCTTAATAAATAACTATCTTTC
AAAATTCCCTAATGTAAAAGATGGAGAGGAAGACTTAGTTGGAATTTCATTTATGAAAGAGTTGACTTTAGTTCTAAAGA
AAAAGATAGAAGAAGAGAAAATGGAAAGACTTATGTATGATATTGAGCTTCCTTTAGAAACAGTTTTATCTTCTATGGAA
TCAATAGGATTTAAAGTAAATAAAGATATTTTAGATGAGTTATCTATTAAGTTTAAAAGAGAGTTAGAGGAAACACAAAA
AGAGATCTTTGAACTTGCAGATGAAGAGTTTAATATAAATTCTCCAAAACAATTAGGTAAGATATTATTTGAAAAATTAG
ATTTACCAGTTATAAAGAAAACTAAAACTGGATATTCAACTAACGCAGAAGTATTAGAAAAGCTTAAGGACAAACATCCT
ATAATAGAAAAAATAACATATTTTAGACAGCTTTCAAAAATATATTCAACTTATGTTGAAGGATTAAAGTCTGTTATAGA
TACAGATGGTTCTATACATTCAACATTTAATCAAACTGTAACTACTACAGGTAGACTTTCATCAACAGAGCCTAATCTTC
AAAATATACCTATAAAATATGAAATGGGTAGAGAAATAAGAAAGGTATTTATACCAAAAGAAGAAGGAGATTTATTAATA
TCAGCTGACTACTCACAAATAGAACTTAGAGTTTTAGCTCATATTTCTGGTGATGAAAATATGATAGATGCATTTAATCA
TCATTCAGATATACACACTAAGACTGCTTCTGAAGTGTTTAAAGTACCAGTTGAAGAGGTAACTCCATTAATGAGAAGTA
GGGCTAAGGCAGTAAACTTTGGTATAGTATATGGAATCGGAGATTTTAGTCTTTCACAGGATTTAAATATTTCAAGAAAA
GAAGCTAAAGAATATATGGATATATATTTTGAAAGATATCCAAAAATTAAAGAGTATATTTCTAAGGTTATTCATGAAGC
TCAAACAAAGGGATATGTATTAACTATGTTAAATAGAAGAAGATATATACCTGAAGCAAATGCTTCAAATAAAATAGTAA
AAGCCCTAGGAGAAAGACTTGCAATGAATGCTCCAATACAAGGAACAGCAGCAGATATAATAAAGCTTGCTATGGTAAAT
GTATATAACAAGTTAAAAGAATTAAATTTAAATAGTAAGTTAATATTACAAGTTCATGATGAACTTATAATAAATGTTGT
CAAAGGAGAATTAGACATTGTTAAGAAACTTCTAAAAGAGGAAATGGAAAATACAATTAAATTAAGTGTACCATTAGATG
TTGATGTTAATGTTGGAGAAGATTGGTATAAGTTAAAATAA

Protein sequence :
MKRLLILDGNSLLNRAFYAVPLLSNSEGTHTNAIYGFTNMLFKMREDIKPDYIVCTFDKKAPTFRHLEYGDYKAGRKKMP
PELAEQFPIVKEMLKLFSITTYELDGFEADDIIGSLAKVAEGEGIEVYIITGDKDALQLAAKDINVCITKKGVSEIEVYN
YDRMVEEYGVTPTQFIDVKGLMGDKSDNIPGVPGVGEKTAFKLIKEYGSVEAVLENIDNISGKKLKENLTEYSEQAIFSK
KLATIMTNVPIDFDLDEIKSKDDYNKDQLKALFTKLQMKSILDKLSNGEEEEPEIEVKITNIENNKKLEDLFNNINEEVY
INFTYLNKEKYSTIEIDKIFINYDEKNYLINFKELAQEEENIKALKEFFENEDILKNGYSIKNALTALKKLGIEFKGLAF
DCELAAYLIDSSKGEYTLLSLINNYLSKFPNVKDGEEDLVGISFMKELTLVLKKKIEEEKMERLMYDIELPLETVLSSME
SIGFKVNKDILDELSIKFKRELEETQKEIFELADEEFNINSPKQLGKILFEKLDLPVIKKTKTGYSTNAEVLEKLKDKHP
IIEKITYFRQLSKIYSTYVEGLKSVIDTDGSIHSTFNQTVTTTGRLSSTEPNLQNIPIKYEMGREIRKVFIPKEEGDLLI
SADYSQIELRVLAHISGDENMIDAFNHHSDIHTKTASEVFKVPVEEVTPLMRSRAKAVNFGIVYGIGDFSLSQDLNISRK
EAKEYMDIYFERYPKIKEYISKVIHEAQTKGYVLTMLNRRRYIPEANASNKIVKALGERLAMNAPIQGTAADIIKLAMVN
VYNKLKELNLNSKLILQVHDELIINVVKGELDIVKKLLKEEMENTIKLSVPLDVDVNVGEDWYKLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 2e-154 44