Gene Information

Name : metC (CPR_0165)
Accession : YP_697502.1
Strain : Clostridium perfringens SM101
Genome accession: NC_008262
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 204547 - 205701 bp
Length : 1155 bp
Strand : +
Note : identified by similarity to GB:AAF14695.1; match to protein family HMM PF01053

DNA sequence : 
ATGAAGAAGAATTCTTTATTAATACATGGGGGTATAAGTATAGATGAAAAAACTGGGGCAGTAAATATTCCAATATATCA
AACATCCACATATAAACAAAGATCTTTTGGGGAAAATAGTGGATATGAATATTCAAGAACAGGAAACCCAACTAGGGAAT
CATTAGAAAAGTTAATTGCAGATATAGAATATGGAAAAAGAGGGTTTGCCTTTGCATCAGGTCTTGCAGCAATTACTGCA
GTATTAAGTTTATTTAAAAGTGGAGATAAATTATTAATTACTAATAATCTTTACGGTGGAACATTTAGAGTAATTGATAA
GATATTCTCTAACTTTGGGATAGGTTATGAAATAATTGATGACTTTAACAATATTGAAGAAAAAATTGATAAGAGTGTTA
AAGCTATTTATATAGAAACACCTACAAATCCTCTGTTAGATGTCATAGATATAAAAATAGCATCAGATAAAGCTAAAAAG
TATAATTTATTAACAATAGTAGATAACACATTTATGACTCCATATTTTCAAAATCCATTAAATCTTGGGGCAGATATAGT
TATTCATTCAGCAACTAAATATCTTGGGGGGCACAGTGATTTAGTTGCTGGGCTTGTAGTTGTGAAAGATGAAGAGCTTG
GAGAAAAAATACACTTTATACAAAACTCTACTGGTGGAATACTTCAACCTTTTGATAGCTTCTTACTAATAAGAGGAATC
AAAACTTTATCAGTAAGAATGGATAGACATGAATTAAATGCTAATTTTATAGCTGAAAAGTTAGGTGACTTAGAGGGAAT
AGATAATGTATATTATCCAGGACTTAAAACTCATATTGGACATGAAATACAAAAGAAACAAGCTTCAGGCTTTGGTGGAA
TAATCTCTTTCACTTTAAATAAGAAATATAATTATGAGAAGTTCTTTAATAGTTTAGAACTTATAACCTTTGGGGAAAGC
TTAGGTGGAGTGGAGTCCTTGGCATGTCACCCAGCTTCTATGACTCATGCAGCTATGCCATTAGAACTTAGAGAACGTAT
AGGAATAACAGATAGGTTAATAAGAATTTCAGTTGGTATAGAAGATAAAGAGGATATTTTAGAAGATATACAACAAGCTT
TAGTAAAGGCTGGTGATAAAAATGAAATATTATAA

Protein sequence : 
MKKNSLLIHGGISIDEKTGAVNIPIYQTSTYKQRSFGENSGYEYSRTGNPTRESLEKLIADIEYGKRGFAFASGLAAITA
VLSLFKSGDKLLITNNLYGGTFRVIDKIFSNFGIGYEIIDDFNNIEEKIDKSVKAIYIETPTNPLLDVIDIKIASDKAKK
YNLLTIVDNTFMTPYFQNPLNLGADIVIHSATKYLGGHSDLVAGLVVVKDEELGEKIHFIQNSTGGILQPFDSFLLIRGI
KTLSVRMDRHELNANFIAEKLGDLEGIDNVYYPGLKTHIGHEIQKKQASGFGGIISFTLNKKYNYEKFFNSLELITFGES
LGGVESLACHPASMTHAAMPLELRERIGITDRLIRISVGIEDKEDILEDIQQALVKAGDKNEIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-88 51
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-89 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_697502.1 cystathionine beta-lyase BAC0207 Protein 1e-58 43