Gene Information

Name : serS (CPR_0014)
Accession : YP_697363.1
Strain : Clostridium perfringens SM101
Genome accession: NC_008262
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 21118 - 22395 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATTTAAAAAAGTTAAGAAGTAATACTGAAGAAGTGAAAAAAGCTTTATCTAATAGAGGAGAAGACTTTGATGT
AAATGTTATAGACGAAGTTATAGCTTTAGATGAAGAAAGAAGAAAAATTTTAGTTGATGTTGAGGCTTTAAAGAAACAAA
GAAATGAAGTATCAGCTGAAATTCCAAAGAGAAAAAAAGCTGGAGAAGACGTTACAGAAGTAATGGCTGAAATGAGAGAA
ATAGGAGATAAAATAAAGGCTGATGATGCTAAAGTTGCTGAGTTAAACGATAAAATTAACTACATCATGCTAAGAATTCC
TAATATACCAAACCCAGCTGTTCCAGAAGGGGAAACTGATGAGGACAATGTTGAAATAAAAAGATGGGGAGAGCCTACTA
AATTCAACTTTGAACCAAAAGCACACTGGGATTTAGGAACAGATTTAGATCTTTTAGACTTCGAAAGAGGTGGAAAGATT
GCTGGATCAAGATTTACAGTTTACAAAGGAATGGGTGCTAGATTAGAGAGATCTATAATAAACTACTTCTTAGATAAACA
CACATTTGAAAATGGATACACTGAAGTATTACCACCATACATGGTAAATAGAGATAGTATGACAGGTACTGGTCAACTTC
CAAAATTCGAAGAAGATGCTTTCAAAGTAGAAAACAATGGATATTTCTTAATACCAACAGCTGAGGTTCCTGTAACTAAT
ATGTACAGAAATGAAACTTTAGAGGGAGATAAACTTCCAATAAAACATGCTGCATATAGTGCTTGTTTCAGAGCAGAAGC
TGGTTCAGCAGGAAGAGATACAAGAGGGCTTATAAGACAACACCAATTTAATAAAGTTGAGTTAGTTAAGTTCTGTAAAC
CAGAGCAAAGCTATGAAGAATTAGATAAATTAGTTCAAGATGCTGAATCTGTATTACAAGGTTTAGGATTACCATATAGA
ATAGTTAGAATATGTAAAGGTGATTTAGGATTCACTGCTGCATTAAAATATGATATAGAAGTTTGGATGCCAAGCTACAA
TAGATATGTTGAAATTTCAAGTTGTTCAAACTTTGAAGATTTCCAAGCTAGAAGAGCTAACATTAAATATAAAAATTCTC
CAAAGGAAAAACCACAATTTGTTCATACATTAAATGGATCAGGGGTTGCTATTGGAAGAACTGTAGCTGCTATATTAGAA
AACTATCAACAAGAAGATGGATCAGTAGTTATACCAGAAGCTTTAAAAGAATATATGAGATGTGATTTATTAAAGTAA

Protein sequence :
MLDLKKLRSNTEEVKKALSNRGEDFDVNVIDEVIALDEERRKILVDVEALKKQRNEVSAEIPKRKKAGEDVTEVMAEMRE
IGDKIKADDAKVAELNDKINYIMLRIPNIPNPAVPEGETDEDNVEIKRWGEPTKFNFEPKAHWDLGTDLDLLDFERGGKI
AGSRFTVYKGMGARLERSIINYFLDKHTFENGYTEVLPPYMVNRDSMTGTGQLPKFEEDAFKVENNGYFLIPTAEVPVTN
MYRNETLEGDKLPIKHAAYSACFRAEAGSAGRDTRGLIRQHQFNKVELVKFCKPEQSYEELDKLVQDAESVLQGLGLPYR
IVRICKGDLGFTAALKYDIEVWMPSYNRYVEISSCSNFEDFQARRANIKYKNSPKEKPQFVHTLNGSGVAIGRTVAAILE
NYQQEDGSVVIPEALKEYMRCDLLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-120 58