Gene Information

Name : smpB (CPR_1291)
Accession : YP_698613.1
Strain : Clostridium perfringens SM101
Genome accession: NC_008262
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1458733 - 1459203 bp
Length : 471 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCAAAGAGAAAAGACAATAAGACATTAGCAGAGAATAGGAAAGCTAGACATGATTACTTTGTTGATGAGGCTATGGA
AGCAGGTATAGCTTTAGTTGGAACAGAGGTTAAGTCTATTAGAAACGGAAGAGTTAATTTAAAGGATTGTTATGCAGATA
TAAATAATGGAGAGATATTTATAAATAATATGCATATAAGTCCTTATGAGCAAGGAAACATATTTAATGTTGATCCTTTA
AGAAAAAGAAAATTACTTCTTCATAAAAGTGAAATTCAAAGATTAATAGGAATAGTTCAACAACAAGGGGTTGCTTTAAT
ACCACTTTCTTTATATTTAAAGAATGGAAGAGTTAAGGTTAACTTAGGGGTTTGTAGAGGTAAGAAAAACTACGACAAGA
GAGATACAATGCTTGAAAAGGCTCATAAGAGAGAGATGGATAGACAACTTAAGGAAAGAAATAGATATTAG

Protein sequence :
MAKRKDNKTLAENRKARHDYFVDEAMEAGIALVGTEVKSIRNGRVNLKDCYADINNGEIFINNMHISPYEQGNIFNVDPL
RKRKLLLHKSEIQRLIGIVQQQGVALIPLSLYLKNGRVKVNLGVCRGKKNYDKRDTMLEKAHKREMDRQLKERNRY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 3e-40 62
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 4e-30 47
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 6e-30 44