Gene Information

Name : panE (CPF_0788)
Accession : YP_695239.1
Strain : Clostridium perfringens ATCC 13124
Genome accession: NC_008261
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 937846 - 938775 bp
Length : 930 bp
Strand : +
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGAAAATCACAATTGTTGGAGCAGGAGCAATGGGCTCACGTTATGGATATATGCTACATGAAGCTGGAAATGAAGTTAT
GCTAATAGATGGGTGGAAGGATCATGTAGATACTATAAACAAAGATGGATTAACTGTTGAGGAAAATGGAGAAATTAAAA
AAGTAAAGATACCAGCAATGCTACCTCAAGATGCTAAAGAAATTCCAGAGTTAATAATATTATTTACTAAATCTATGGGA
TTAGAACCAATGTTAGAATCTATAAAAGGTATATTAGGAAAAAATACAAAAGTATTATGCCTATTAAATGGATTAGGACA
TAATGAAACTGTAGCAAAATATGTTGATAACAAAAACATACTTATGGGAGTAACTTTATGGACAGCTGGGTTAAAAGGTC
CAGGACATGTTGTATTAACAGGAAGTGGAAGCCTAGAAGTTCAAAATATTGATCCAAGTATGGAAAAAGAGGCAAAAGAA
ATTTGCGATATATTAAGTAATGCTGGATTAAAAGCTCACTATAGTGAAAATGTATTATTTTCAATATGGCGTAAAGCTTG
CGTAAATGGAACTTTAAATAGTGGATGTACAATTTTAGATTGTAATATTAAAGAATTTGGTGAATTAAAGGAAGCTCCAC
AACTTATACGTAATATTATAAAAGAATTTGCTGATATTGCAGCTGAATATGGAGTAAAATTAGATGTTGAAGAGGTTGCA
AGAGGTATAGAGGCAATATATGATCCAAGCCAAGCTGGCGCTCACTATCCATCAATGCATCAAGATTTAATACAAAATCA
TCGTCTTACAGAAATAGATTATATAAATGGTTATGTATCAAGAAAAGGTAAAGAGTTTAATATAAATACACCATATAATG
ACTTACTTACTACTCTTGTTCATGCAAAAGAGCAATTACTTATTAAATAA

Protein sequence :
MKITIVGAGAMGSRYGYMLHEAGNEVMLIDGWKDHVDTINKDGLTVEENGEIKKVKIPAMLPQDAKEIPELIILFTKSMG
LEPMLESIKGILGKNTKVLCLLNGLGHNETVAKYVDNKNILMGVTLWTAGLKGPGHVVLTGSGSLEVQNIDPSMEKEAKE
ICDILSNAGLKAHYSENVLFSIWRKACVNGTLNSGCTILDCNIKEFGELKEAPQLIRNIIKEFADIAAEYGVKLDVEEVA
RGIEAIYDPSQAGAHYPSMHQDLIQNHRLTEIDYINGYVSRKGKEFNINTPYNDLLTTLVHAKEQLLIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 4e-78 52
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 3e-78 52