Gene Information

Name : leuS (CPF_0657)
Accession : YP_695110.1
Strain : Clostridium perfringens ATCC 13124
Genome accession: NC_008261
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 786159 - 788609 bp
Length : 2451 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGGTAACTATAGTACTGCCATAGATAAGAAATGGCAAGAAAAATGGGCTGAATCAGGCCTTTATAAATTTGATCCAAA
TAAAGAAGGAGAGAAACTTTACGTTTTAGAAATGTTTTCATACCCTTCAGGTAGCCAATTACATGCAGGTCACTGGTTTA
ACTATGGACCAGTTGATTCATGGGCTAGATTTAAAAGAATGCAAGGATATAATGTATTCCAACCAATGGGATTTGATGCT
TTCGGTTTACCTGCTGAAAACTTTGCTATAAAAACAGGAATACATCCTCAAGATTCTACAATAAAAAATATAGCTAAAAT
GGAAGAACAATTAAAAGCTATGGGAGCTATGTTTAACTGGGAAAACGAAGTTGTAACTTGCTCACCTGAATATTATAAAT
GGACTCAATGGCTATTCCTAAAATTATACGAAAAAGGATTAGCTTATAGAAAAAAAGCTCCTGTAAACTGGTGTCCATCA
TGTCAAACAGTTCTTGCTAATGAGCAAGTAGTTGATGGAGCTTGTGAAAGATGTTCAACAGAAGTTACTAAAAAAGATCT
TACTCAATGGTTCTTTAAAATAACTGATTATGCTGATGAATTATTAGATAAATTAGATGATTTAGATTGGCCAGAAAAAA
CAGTTTCTATGCAAAAACACTGGATAGGAAGATCAACTGGTTCTCAAGTTAACTTTAAAGTTAAAGATAGCGATTTAAAC
TTTGATGTATTCACAACAAGAGTTGATACTTTATGCGGAGTTAGCTATGTTGTTTTAGCTCCTGAAAATCCATTAGTAGA
CGAAATAGTTTCAGCTGAACAAAAAGAAGCTGTTGAAAATTATAAAGAAGAAGCTAAAAAACAATCTGATATAGAAAGAC
AATCTATTTCAAGAGAAAAAACGGGTGTATTCACTGGTGCATATGCTATTCATCCATTAACAGGTAAAGAAGTTCCTATA
TGGGTTGGAGACTACGTTCTAGCAACTTACGGAACTGGAGCTGTTATGGCTGTTCCTGCTCATGATGAAAGAGATTTTGC
TTTTGCTGAAAAATTCAACCTTCCAATAAATAGAGTTATAGAAGCTAAAGATGGTAGTGAAACTAACCTTCCATTCTGCG
AGCACGGTATATTAGTTAACTCAGGTGAATTTGATGGATTAACTACAGATGAAGCTAAAGAAAAAATAGTTGAAAAACTA
GCTTCAATGGGTCTTGGAGAAAAGAAAGTTAACTTTAGATTAAGAGACTGGTTAGTTTCAAGACAAAGATACTGGGGAGC
TCCAATTCCTGTAGTTTACTGTGAAGAATGTGGTATAGTTCCTGTACCTGAAAGTCAATTACCAGTTGAATTACCATATG
ATGTTGAATTTGCTCCAGATGGAAAATCTCCACTAGCTAAGAGCGAAGCATTTGTTAATACAACTTGCCCTCACTGTGGA
AAACCAGCTAAGAGAGAAACTGATACTTTAGATACTTTCGTATGTTCATCATGGTATTACTTAAGATATCCTGATAATAA
AAATACTGAGGCTCCATTTAATCCTGAATTAATCAACAAAATGTTACCAGTTGATAAATACGTTGGTGGACCTGAACATG
CTTGTATGCATCTTCTTTACGCAAGATTCATAACTAAAGCCCTAAGAGATATGGGATACCTAAACTTTGATGAACCATTT
ACTTCATTAACTCACCAAGGATTAATCTTAGGACCAGACGGATTAAAAATGAGTAAATCAAAAGGAAATACAATATCTCC
TGATGATTATATAAAAGAATATGGTGCAGATGTATTTAGAATGTACCTAATGTTTGGTTTTGCTTACACTGAAGGTGGAG
CTTGGAGTGATGATGGAATCAAATCTGTAAATAGATTCGTTGAAAGAATTGAAAGAATTATAGATACTGCTAGAGAAGCA
ATCTCAAAAGGTGAAAATAATAAAACTACAATGGATAAGGCTGAAAAAGAGCTTAACTATTGGAGACACAATACTATAAA
ATCTGTTACAGATGATACAGATAAACTTCAATTTAATACAGCAATAGCTAGAATGATGGAATTCATAAATGCTTTATCTA
AATATACTCAAGAGAAAGAAATGAATCTTGATTTCTTAAAAGATGTAGTTTCTGATTATTTAAGATTATTAGCACCATTT
GCACCTCACTTCAGTGAAGAACAATGGAGCTTACTTGGAAATTCATACTCAATCTTCAATGAAGCATGGCCAAAATTTGA
CCCTAAAGCTTTAGTTAAAGACGAAGTTGAAATAGCTATACAAGTTAACGGAAAAATCAAAAACAAAATAATGGTTTCTT
CTGATTTAGATGAAGAAGGAATAAAAGCCGCTGCTTTAGCTGATGAGAAAATCATAGCTTCAACAGAAGGAAAAACAGTT
GTAAAAGTAATAGTTATAAAAGGTAGACTTGTAAATATAGTTGTTAAGTAA

Protein sequence :
MGNYSTAIDKKWQEKWAESGLYKFDPNKEGEKLYVLEMFSYPSGSQLHAGHWFNYGPVDSWARFKRMQGYNVFQPMGFDA
FGLPAENFAIKTGIHPQDSTIKNIAKMEEQLKAMGAMFNWENEVVTCSPEYYKWTQWLFLKLYEKGLAYRKKAPVNWCPS
CQTVLANEQVVDGACERCSTEVTKKDLTQWFFKITDYADELLDKLDDLDWPEKTVSMQKHWIGRSTGSQVNFKVKDSDLN
FDVFTTRVDTLCGVSYVVLAPENPLVDEIVSAEQKEAVENYKEEAKKQSDIERQSISREKTGVFTGAYAIHPLTGKEVPI
WVGDYVLATYGTGAVMAVPAHDERDFAFAEKFNLPINRVIEAKDGSETNLPFCEHGILVNSGEFDGLTTDEAKEKIVEKL
ASMGLGEKKVNFRLRDWLVSRQRYWGAPIPVVYCEECGIVPVPESQLPVELPYDVEFAPDGKSPLAKSEAFVNTTCPHCG
KPAKRETDTLDTFVCSSWYYLRYPDNKNTEAPFNPELINKMLPVDKYVGGPEHACMHLLYARFITKALRDMGYLNFDEPF
TSLTHQGLILGPDGLKMSKSKGNTISPDDYIKEYGADVFRMYLMFGFAYTEGGAWSDDGIKSVNRFVERIERIIDTAREA
ISKGENNKTTMDKAEKELNYWRHNTIKSVTDDTDKLQFNTAIARMMEFINALSKYTQEKEMNLDFLKDVVSDYLRLLAPF
APHFSEEQWSLLGNSYSIFNEAWPKFDPKALVKDEVEIAIQVNGKIKNKIMVSSDLDEEGIKAAALADEKIIASTEGKTV
VKVIVIKGRLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-170 47