Gene Information

Name : clpC (CPF_2751)
Accession : YP_697129.1
Strain : Clostridium perfringens ATCC 13124
Genome accession: NC_008261
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence MecB/ClpC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : 3.4.21.-
Position : 3010907 - 3013351 bp
Length : 2445 bp
Strand : -
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGCGTCTTGATAATTTTAATGAAAATTCCAAAATAGTAATCAATAAGGGAAAAGAAAGTTCTTTAATGCTAAAACACGG
CTACATGGGAACAGAGCATTTATTAATAGGATTAATTAATGAAAATGGACAATGTTCTAAAATTTTGGAAGAAAGCAATG
TAACTGAAGAAAAGGTACTTAGTTTTATTAAGCTATATGTTGGAATTGGAGAGGTAAATTATAGTTTGGATGAGGTGCCT
TTTACACCTAGATGCAAAAAGATTTTAGATAGAAGTGTTGAAATTGCTAAGGAATATGGTCATAGCATTTCAAGACCAGA
GCACATATTATTAGCCTTAATAAAAGAAAGAGAAGGTGTAGCTAATTTAATTCTAACTAAAATAGTAAAAAATGATATAA
AAAATATAAGCGATAAGTTAAATAACATACTAGGTAGAATTCCAAGTAAGGAAAGTAAAAGCCTTAAAGAAAAGGAAAAA
CCAAAAAGAAAAGATACTCCTACATTAAATCTTTATGGTATAAATTTAATAGAAAAGGCAGATAAAAATAAACTTGATCC
TGTAATAGGGAGAAAGGATGAAACTCAAAGACTTTTAGAAATACTTTGTAGAAGAATGAAAAACAATCCTTGTTTAATAG
GAGAACCTGGAGTAGGAAAAACTGCCGTTGTAGAAGGATTAGCTCAAAGAATTCTATTAGGTGAAGTACCAGATATTATT
AAGGATAAAAGAATATTTACCTTAGATGTGACTTCTATGTTAGCTGGGGCAAAATATAGAGGAGAATTTGAGGAAAGACT
TAAAAAGGTTTTAAACGAAGTAAAAGATTCAGATGATATAATACTCTTTATAGATGAAATGCATAATATTGTTGGGGCTG
GGGGAGCAGAAGGTGCTATAGATGCATCAAATATATTAAAACCAGCTTTAGCAAGAGGTGAAATACAATGTATAGGTGCA
ACAACAACTGATGAATATAGAAAAAATATAGAAAAGGATTCTGCTTTGGAGAGAAGATTTCAACCAGTAGTTGTAAAAGA
GCCTAGTAAAGAAGATTCCGTATTAATATTAAAGGGATTAAGAGAAAAGTATGAAGTACATCACAATGTAAAATTAACAG
ATGAAGCCATAGAGGCAGCTGTTAATTTATCAAGTAGATATATAACCGATAGATTTCTACCAGATAAGGCCATAGATCTA
ATAGATGAGGCTGCGGCTAAGGTAAGAATAGAAAGTATGATTGTTCCTCCTAGACTTTTTAAGCAGGAAGAATTAATAGC
TAACTTAAAAATTGAAAAAGAAGAAGCTATAAAATTACAGGACTTTGAATTAGCTGCAAAGTTAAGAGATGAAGAATCAA
TGTTACAGGAAGAACTAGAGCGAGATAAAGAACTTTGGAGAGAAGAAAATTACAATAAAATCTACGAAGTTAATAAAGAA
CATATTGCAAAGGTTGTTTCAAAGTGGACTCAGATACCAGTAGAAAGGCTTACAGAGAAAGAATCAAGTAAACTTCTTAA
GCTGGAAGAAAAGCTTAGTAAAAGAGTTATAGGACAATTAGAAGCAATAAGAACCATATCTAAAGCTGTAAGAAGATCAA
GGGTAGGTCTTAAAGATCCTAAGAGACCTATTGGATCCTTTGCCTTTTTAGGACCTACTGGAGTAGGAAAAACAGAGCTT
TGTAAGGCTTTAGCAGAGGCTATGTTTGGTGATGAGAATAAATTTATTAGGCTTGATATGTCTGAATACATGGAAAAGCA
TGGTGTATCTAGACTTATTGGAGCTCCCCCAGGATATGTAGGATATGAAGAGGGAGGACAACTTACAGAAAAGGTAAGAA
GAAATCCTTACTCAGTAATACTTTTTGATGAAATAGAAAAAGCACATCCAGATATATTTAATGTTCTTCTTCAAATATTA
GAAGATGGTGTTCTTACAGATGGAAAAGGTAAAACAGTAGATTTTAAGAATACAATAATCATAATGACTTCAAATATTGG
AGCAGATAAATTAGATAAGAAAAATGCAGTTGGATTTAGTGCTAAAGAGGATAAGGAACGAGATTATGATAAGATGAAAG
GAATTATGTTAGAAGAGCTAAAACAAAATTTCAAACCTGAATTTGTAAATAGATTAGATGACATAGTTGTATTCCATAGT
CTAGAAAAGGATCATCTTTTAAAAATTGTTGATCTTATGATATGTTCTCTAAAAGAGAGGTTAAATGATTTACAACTTTC
TTTGAATTTTTCTCAAGAGTGTAAAGAATTTTTAGTTAAAAAGGGCACTGAATTAAAATATGGAGCACGTCCATTAAGAA
GAGTTATAACTAAATATATTGAAGATAGATTAAGTGAAGAACTTTTAAGTGGAAATATATTAAGAGGATCTAAGGTAGAT
GTTTTCTTAGAAGACGACGTTGTAAAATTTAAAAAAACTGTTTGA

Protein sequence :
MRLDNFNENSKIVINKGKESSLMLKHGYMGTEHLLIGLINENGQCSKILEESNVTEEKVLSFIKLYVGIGEVNYSLDEVP
FTPRCKKILDRSVEIAKEYGHSISRPEHILLALIKEREGVANLILTKIVKNDIKNISDKLNNILGRIPSKESKSLKEKEK
PKRKDTPTLNLYGINLIEKADKNKLDPVIGRKDETQRLLEILCRRMKNNPCLIGEPGVGKTAVVEGLAQRILLGEVPDII
KDKRIFTLDVTSMLAGAKYRGEFEERLKKVLNEVKDSDDIILFIDEMHNIVGAGGAEGAIDASNILKPALARGEIQCIGA
TTTDEYRKNIEKDSALERRFQPVVVKEPSKEDSVLILKGLREKYEVHHNVKLTDEAIEAAVNLSSRYITDRFLPDKAIDL
IDEAAAKVRIESMIVPPRLFKQEELIANLKIEKEEAIKLQDFELAAKLRDEESMLQEELERDKELWREENYNKIYEVNKE
HIAKVVSKWTQIPVERLTEKESSKLLKLEEKLSKRVIGQLEAIRTISKAVRRSRVGLKDPKRPIGSFAFLGPTGVGKTEL
CKALAEAMFGDENKFIRLDMSEYMEKHGVSRLIGAPPGYVGYEEGGQLTEKVRRNPYSVILFDEIEKAHPDIFNVLLQIL
EDGVLTDGKGKTVDFKNTIIIMTSNIGADKLDKKNAVGFSAKEDKERDYDKMKGIMLEELKQNFKPEFVNRLDDIVVFHS
LEKDHLLKIVDLMICSLKERLNDLQLSLNFSQECKEFLVKKGTELKYGARPLRRVITKYIEDRLSEELLSGNILRGSKVD
VFLEDDVVKFKKTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 50
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-89 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_697129.1 negative regulator of genetic competence MecB/ClpC VFG0079 Protein 0.0 53
clpC YP_697129.1 negative regulator of genetic competence MecB/ClpC VFG0080 Protein 2e-149 53