Gene Information

Name : polA (CPF_2250)
Accession : YP_696673.1
Strain : Clostridium perfringens ATCC 13124
Genome accession: NC_008261
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 2496982 - 2499582 bp
Length : 2601 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGAAAAGATTATTGATATTAGACGGGAACAGTCTTTTAAATAGAGCCTTTTATGCTGTGCCTTTGCTTAGCAATAGTGA
AGGAACTCATACAAATGCTATTTATGGTTTTACAAATATGCTTTTTAAGATGAGAGAGGATATAAAACCTGATTATATAG
TTTGTACTTTTGATAAAAAAGCACCAACTTTTAGACATTTAGAGTATGGGGATTATAAGGCTGGAAGAAAGAAAATGCCT
CCTGAGTTAGCAGAGCAGTTTCCTATTGTTAAGGAAATGCTAAAGTTATTTTCAATAACAACTTATGAATTAGATGGATT
CGAAGCAGATGATATTATAGGAAGTTTAGCTAAGGTGGCTGAAGGTGAAGGAATCGAAGTTTATATTATGACTGGAGATA
AGGATGCCCTTCAACTAGCAGCTAAGGATATAAATGTATGTATAACTAAGAAGGGTGTTTCTGAAATAGAAGTTTATAAC
TATGATAGAATGGTTGAAGAATATGGAGTTACTCCTACTCAGTTCATAGATGTTAAAGGACTTATGGGAGATAAATCTGA
TAATATTCCAGGGGTACCAGGAGTAGGAGAAAAAACAGCCTTTAAATTAATAAAAGAGTATGGTTCAGTAGAGGCAGTTT
TAGAAAATATAGATAACATAAGTGGTAAAAAGTTAAAAGAAAATTTAACTGAGTACAGCGAACAGGCTATATTCTCTAAA
AAGTTAGCTACTATTATGACTAATGTTCCTATAGATTTTGATTTAGATGAGATTAAATCAAAGGATGATTATAATAAAGA
TCAGTTAAAAGCTTTATTTACAAAGCTTCAAATGAAATCTATATTAGATAAATTATCAAATGGGGAAGAAGAAGAGCCAG
AAATAGAAGTTAAAATAACTAATATAGAAAATAGTAAAGAATTAGAAGAGTTATTTAAGAATATAAACGAAGAAGTATAT
ATTAATTTTACTTATTTAAATAAAGAAAAGTATTCTACTATAGAGATTGATAAAATATTTATTAATTATGATGAGAAAAA
TTATTTAATTAACTTTAAAGAGTTAGTAAAAGAAGAGGAGAATATTAAATCCTTTAAAGAATTTTTTGAGAATGAAGATA
TATTAAAAAATGGCTATAGTATAAAAAATGCCTTAACAGCATTAAAAAAATTAGGAATAGATTTTAATGGATTAGCCTTT
GATTGTGAATTAGCAGCATATTTAATAGATTCATCTAAGGGAGAATATACTCTTTTATCCTTAATAAATAACTATCTTTC
AAAATTCCCTAATGTAAAAGAGGGGGAAGAAGACTTAGTTGGAATTTCATTTATGAAAGAGTTGACTTTAGTTCTAAAGA
AAAAGATAGAAGAAGAGAAAATGGAAAGACTTATGTATGATATTGAGCTTCCTTTAGAAACAGTTTTATCTTCTATGGAA
TCAATAGGGTTTAAAGTAAATAAAAATATTTTAGATGAGCTATCTATTAAGTTTAAAAGAGAGTTAGAGGAAACACAAAA
AGAGATCTTTGAACTTGCAGATGAAGAGTTCAACATAAATTCTCCAAAACAATTAGGTAAGATATTATTTGAAAAATTAG
ATTTACCAGTTATAAAGAAAACTAAAACTGGCTATTCAACTAACGCAGAAGTTTTAGAAAAGCTTAAGGACAAACATCCT
ATAATAGAAAAAATAACATATTTTAGACAGCTTTCAAAAATATATTCAACTTATGTTGAAGGATTAAAGTCTGTTATAGA
TACAGATGGTTCTATACATTCAACATTTAATCAAACTGTAACTACTACAGGTAGACTTTCATCAACAGAGCCTAATCTTC
AAAATATACCTATAAAATACGAAATGGGTAGAGAAATAAGAAAGGTATTTATACCAAAAGAAGAAGGAGATTTATTAATA
TCAGCTGACTACTCACAAATAGAACTTAGAGTTTTAGCTCATATTTCTGGTGATGAAAATATGATAGATGCATTTAATCA
TCATTCAGATATACACACTAAGACTGCTTCTGAAGTATTTAAAGTTCCAGTTGAAGAGGTAACTCCATTAATGAGAAGTA
GGGCTAAGGCAGTAAACTTTGGTATAGTATATGGAATAGGAGATTTTAGTCTTTCACAGGATTTAAATATTTCAAGAAAA
GAAGCTAAAGAATATATGGATATATATTTTGAAAGATATCCAAAAATTAAAGAGTATATTTCTAAGGTTATTCATGAAGC
TCAAACAAAGGGATATGTATTAACTATGTTAAATAGAAGAAGATATATACCTGAAGCAAATTCTTCAAATAAAATAGTAA
AAGCCTTAGGAGAAAGACTTGCAATGAATGCTCCAATACAAGGAACAGCAGCAGATATAATAAAACTTGCTATGGTAAAT
GTATATAACAAGTTAAAAGAATTAAATTTAAATAGTAAGTTAATATTACAGGTTCATGATGAACTTATAATAAATGTTGT
AAAAGGAGAATTAGACATTGTTAAGAAACTTCTAAAAGAGGAAATGGAAAATACAATTAAATTAAGTGTACCATTAGATG
TTGATGTTAATGTTGGAGAAGATTGGTATAAGTTAAAATAA

Protein sequence :
MKRLLILDGNSLLNRAFYAVPLLSNSEGTHTNAIYGFTNMLFKMREDIKPDYIVCTFDKKAPTFRHLEYGDYKAGRKKMP
PELAEQFPIVKEMLKLFSITTYELDGFEADDIIGSLAKVAEGEGIEVYIMTGDKDALQLAAKDINVCITKKGVSEIEVYN
YDRMVEEYGVTPTQFIDVKGLMGDKSDNIPGVPGVGEKTAFKLIKEYGSVEAVLENIDNISGKKLKENLTEYSEQAIFSK
KLATIMTNVPIDFDLDEIKSKDDYNKDQLKALFTKLQMKSILDKLSNGEEEEPEIEVKITNIENSKELEELFKNINEEVY
INFTYLNKEKYSTIEIDKIFINYDEKNYLINFKELVKEEENIKSFKEFFENEDILKNGYSIKNALTALKKLGIDFNGLAF
DCELAAYLIDSSKGEYTLLSLINNYLSKFPNVKEGEEDLVGISFMKELTLVLKKKIEEEKMERLMYDIELPLETVLSSME
SIGFKVNKNILDELSIKFKRELEETQKEIFELADEEFNINSPKQLGKILFEKLDLPVIKKTKTGYSTNAEVLEKLKDKHP
IIEKITYFRQLSKIYSTYVEGLKSVIDTDGSIHSTFNQTVTTTGRLSSTEPNLQNIPIKYEMGREIRKVFIPKEEGDLLI
SADYSQIELRVLAHISGDENMIDAFNHHSDIHTKTASEVFKVPVEEVTPLMRSRAKAVNFGIVYGIGDFSLSQDLNISRK
EAKEYMDIYFERYPKIKEYISKVIHEAQTKGYVLTMLNRRRYIPEANSSNKIVKALGERLAMNAPIQGTAADIIKLAMVN
VYNKLKELNLNSKLILQVHDELIINVVKGELDIVKKLLKEEMENTIKLSVPLDVDVNVGEDWYKLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 4e-155 44