Gene Information

Name : CPF_0156 (CPF_0156)
Accession : YP_694620.1
Strain : Clostridium perfringens ATCC 13124
Genome accession: NC_008261
Putative virulence/resistance : Virulence
Product : perfringolysin O
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 184140 - 185642 bp
Length : 1503 bp
Strand : +
Note : identified by similarity to SP:P19995; match to protein family HMM PF01289

DNA sequence :
ATGATAAGATTTAAGAAAACAAAATTAATAGCAAGTATTGCAATGGCTTTATGTCTGTTTTCTCAACCAGTAATCAGTTT
CTCAAAGGATATAACAGATAAAAATCAAAGTATTGATTCTGGAATATCAAGTTTAAGTTACAATAGAAATGAAGTTTTAG
CTAGTAATGGAGATAAAATTGAAAGCTTTGTTCCAAAGGAAGGTAAAAAAGCTGGTAATAAATTTATAGTTGTAGAACGT
CAAAAAAGATCCCTTACAACATCACCAGTAGATATATCAATAATTGATTCTGTAAATGACCGTACATATCCAGGAGCATT
ACAACTTGCAGATAAAGCATTTGTGGAAAATAGACCTACAATCTTAATGGTAAAAAGAAAGCCTATTAACATTAATATAG
ATTTACCAGGATTAAAGGGCGAAAATAGTATAAAGGTTGATGATCCAACCTATGGAAAAGTTTCTGGAGCAATTGATGAA
TTAGTATCTAAGTGGAATGAAAAGTATTCATCTACACATACTTTACCAGCAAGAACTCAATATTCAGAATCTATGGTTTA
TAGTAAATCACAAATATCAAGTGCCCTTAATGTTAATGCTAAAGTCCTTGAAAACTCACTTGGAGTAGACTTTAATGCAG
TAGCAAACAATGAGAAAAAAGTTATGATTTTAGCATATAAACAAATATTCTATACAGTAAGTGCAGATTTACCTAAGAAT
CCATCAGATCTTTTTGATGACAGTGTTACATTTAATGATTTAAAACAAAAGGGAGTAAGTAATGAAGCACCTCCACTTAT
GGTTTCAAATGTAGCTTATGGAAGAACAATATATGTTAAGTTAGAAACTACTTCTAGTAGTAAAGATGTACAAGCTGCTT
TCAAAGCTCTTATAAAGAACACTGATATAAAAAATAGTCAACAATATAAAGATATTTATGAAAATAGTTCCTTCACAGCA
GTAGTTTTAGGAGGAGATGCACAAGAACATAACAAAGTTGTAACTAAAGACTTTGATGAAATAAGAAAAGTAATTAAAGA
CAATGCAACTTTTAGTACAAAAAACCCAGCATATCCAATATCTTATACTAGTGTTTTCTTAAAAGATAACTCAGTTGCTG
CTGTTCACAATAAAACAGATTATATAGAAACAACTTCTACAGAGTATTCTAAGGGAAAAATAAACTTAGATCATAGTGGA
GCCTATGTTGCACAGTTTGAAGTAGCCTGGGATGAAGTTTCATATGACAAAGAAGGAAATGAAGTTTTAACTCATAAAAC
ATGGGATGGAAATTATCAAGATAAAACAGCTCACTATTCAACAGTAATACCTCTTGAAGCTAATGCAAGAAATATAAGAA
TAAAAGCAAGAGAGTGTACAGGCCTTGCTTGGGAATGGTGGAGAGATGTTATAAGTGAATATGATGTTCCATTAACAAAT
AATATAAATGTTTCAATATGGGGAACAACTTTATACCCTGGATCTAGTATTACTTACAATTAA

Protein sequence :
MIRFKKTKLIASIAMALCLFSQPVISFSKDITDKNQSIDSGISSLSYNRNEVLASNGDKIESFVPKEGKKAGNKFIVVER
QKRSLTTSPVDISIIDSVNDRTYPGALQLADKAFVENRPTILMVKRKPININIDLPGLKGENSIKVDDPTYGKVSGAIDE
LVSKWNEKYSSTHTLPARTQYSESMVYSKSQISSALNVNAKVLENSLGVDFNAVANNEKKVMILAYKQIFYTVSADLPKN
PSDLFDDSVTFNDLKQKGVSNEAPPLMVSNVAYGRTIYVKLETTSSSKDVQAAFKALIKNTDIKNSQQYKDIYENSSFTA
VVLGGDAQEHNKVVTKDFDEIRKVIKDNATFSTKNPAYPISYTSVFLKDNSVAAVHNKTDYIETTSTEYSKGKINLDHSG
AYVAQFEVAWDEVSYDKEGNEVLTHKTWDGNYQDKTAHYSTVIPLEANARNIRIKARECTGLAWEWWRDVISEYDVPLTN
NINVSIWGTTLYPGSSITYN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
slo YP_281505.1 streptolysin O Virulence Not named Protein 5e-156 67
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 4e-104 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CPF_0156 YP_694620.1 perfringolysin O VFG2275 Protein 0.0 99
CPF_0156 YP_694620.1 perfringolysin O VFG0976 Protein 2e-156 67
CPF_0156 YP_694620.1 perfringolysin O VFG1363 Protein 3e-110 47
CPF_0156 YP_694620.1 perfringolysin O VFG0074 Protein 2e-104 44