Gene Information

Name : ABO_2630 (ABO_2630)
Accession : YP_694350.1
Strain : Alcanivorax borkumensis SK2
Genome accession: NC_008260
Putative virulence/resistance : Resistance
Product : AcrB/AcrD/AcrF family transporter
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 2976274 - 2979342 bp
Length : 3069 bp
Strand : -
Note : (AcrB/C/D family cation/multidrug efflux pump; Transporter of the RND family of multidrug efflux pump) identified by match to PFAM protein family HMMPF03626 InterPro: Acriflavin resistance protein; Family membership

DNA sequence :
ATGAACATTGCCGAGTACAGTATTCGCCACAAGGTGGTGAGCTGGCTGTTCACGCTGATCTTGTTGATCGGTGGGGTGGT
GAGCTTTACCCGCTTAGGGCAACTGGAAGACCCGGAATTCACCCTCAAGATTGCCATGGTGGTTACTAACTACGCTGGTG
CTTCACCCCGACAGGTGGAAGAGGAAGTGACACTGCCGGTGGAGAAAGCGATCCAGAGTCTGCCTTATGTGAAAAATGTG
ACGTCCATTTCTAGCAATGGCCTGTCTCAGGTGCAGGTAGAAATGAAGCCCGAGTACCGGGCCGCCGAGCTCAAGCAGAT
TTGGGATGAGCTGCGCCACAAGATGACCGACTTGCAGGATCAGTTGCCTCCTGGTGCGGGGACGATTCAAGTTATTGATG
ATTTCGGTGATGTGTACGGCATTCTTTTGGCCGTAACCGGCGGCGGTTACTCCTACCAAGACATGAAAGATTATGCCGAC
TACCTGACTCGCGAACTGGTGCTTGTAGATGGGGTCGGCAAGGTCACTATTGGCGGGCAGCGACAGGAGCAGGTGCTGGT
GGAGCTTTCCCGCTCTCGGTTGGCGTCATTGGGAATCAGCCCTGACCGTATTTTCGGCCTGTTACAAACCCAGAATAAGG
TGAACCCGGCGGGCAAAGTGCGGGTGGGTGACGAATACATCCGTATTTACCCCACCGGTGAGTTTCCTTCCGTGCAAAGC
ATGGGCGATTTGTTGATTTCCGAGCCCGGCGCTAGCGAGTTGGTCTACCTGCGCGATGTGGCGACGATCGAGCGCGGCTA
TGCGGAAGTGCCTTACCATCTGTATCGCTTTAATGGTGGCTCGGCACTGACCATGGGGATTTCCTTTGCCTCGGGTGTGA
ACGTTGTGGATGTTGGGGCTCGGGTGGATCGGCGCTTGGCCGAGCTTGAGTATCAGCGCCCTGCGGGCATGCAGTTGGCC
ACGGTCTACAACCAGCCCAAAGAAGTCGATAATTCGGTGAGCGCTTTCATGCTCAATTTGGGTGAAGCCGTGGCCATTGT
GATCGCGGTGCTGCTCGTGTTCATGGGGGTGCGGTCCGGGATATTGATGGGCAGCGTGTTGCTGCTCACCATCCTTGGCA
CGTTCATCATCATGAAAGTTATGGCCATCGATCTGCAGCGAATTTCGCTCGGGGCGCTAATTATTGCTCTAGGGATGCTG
GTGGATAACGCCATCGTGGTTACCGAAGGCATTCTGGTGGGCATGAAACGCGGGTTGTCCAAGCTGGAGGCGTCGAAAGA
AATTGTTCGGCAAACCGTTTGGCCGCTGCTGGGTGCCACTGTCATCGCTATTATGGCGTTTGCTCCGATCGGTTTATCGG
AGGATGCCACTGGCGAATACAGTAATACCTTGTTCTGGGTATTGCTGATTTCTTTGATGCTCAGCTGGGTGACGGCTATT
ACGCTGGTGCCGTTTTTTGCCGACCTGTTTTTCAATGAGAAAGACGTGGGAGGTAAAAATGGCGAAAGTGAGGATCCCTA
CTCTGGCAAAGTGTTTGTCATTTATCGGCGCTTGCTGGATCGGGCGATCCACCACCGGGTGATCACCTTGAGCTTTATGA
GCGTGCTGTTGGTGGTGGCCGTTGTCGGTTTTGGTTTCGTGAAGCAAGCGTTCTTCCCGCCCTCCAATACTCCCATGTTT
CTAGTGGACTACTGGCTACCCCAAGGGAGCGATATCCGTGCTACCCAAGAGGCGGCTGCGCGGTTAGAGCATGATTTGCT
GGAGATGGATAGTGTGGAGCAGGTGACCACGACTATCGGTCAGGGGGCACAGCGTTTCATGCTGCCCTATATGCCTGAAA
AAAGTTACTCCAGCTATGCGCAGTTGATCGTGCAGGTGTCCGACCGGGAGCAGATCGATCCGACCCTAGCGGCGACCCGT
GAGCTGATTCGCGACCGACACCTGCAAGCGTTCGCTAAAGTGAAACGCCTGATGATCGGCCCCAGCCCGGCGGCCTCTAT
TGAAGCCCGCTTCAGTGGCCCGGACCCAAAAGAGCTGCGGGCGTTGGGCGTGAAAGCCCAAGCGATTATGCAAGCTGATA
GTGGGCTGGAAAGCATCCGCCACGACTGGCGTCAGCAGGAAAAAGTGATTCGCCCCCAGTTCCAGGAAGCTCAGGCCCGC
CGTGCTGGGATTACCCGCGAGGACTTGGATAATACCCTGGCACTGAACTTTAGCGGTCGCAATGTGGGCCTGTACCGTGA
TGGCAGCAAGTTGTTGCCGATTGTGGCGCGGCCGCCAGACGATGAGCGCCTGAGTGCGGATAACCTTAACGATGTACAGG
TTTGGTCGCCGGCCTATTCGACCTATATTCCCATCAGTCAGGTGGTCTCGGATTTCAAGACCGAATGGGAAAATGCGTTG
ATCATGCGTCGTGATCGCAAACGAACGCTTACCGTGCAGGCCGAGCCGGATGTGCTTGGCGAGGAGACCGCGGATCAGGT
GCTGCGGCGGATTCGCCCGGCCATCGAAGCTCTGGAGCTGCCGCCGGGTTACTCCCTCCAGTGGGGTGGGGAATACGAAG
CCGCTAAGGATGCTCAGGCTGCGGTATTCGGCAGTCTGCCCATGGGCTATTTGTTCATGTTCATCATTACCATCATGTTG
TTCGACGCAGTGCGCTCGCCATTGGTGATCTGGGCCACGGTGCCGTTGGCCATTATCGGTGTGACCTTTGGCCTGCTGGT
GCTCAATTCACCGTTTGGCTTTATGGCGCTGTTGGGATTTCTGAGCTTGTCTGGGATGTTGGTGAAGAACGGTATTGTGC
TGGTGGAACAAATCAAGCTGGACCGCGAGAGGCTGGCGCCGTTCGATGCAGTGGTGTCGGCATCCATTTCGCGGGTGCGA
CCGGTGTGTATGGCGGCGATTACCACCATCCTTGGCATGGTGCCGCTGCTGTTCGACGCGTTCTTCGAGTCGATGGCGGT
GGTGATCATGTTTGGCTTGGGCTTCGCTACCGTGCTGACATTGATCGTGGTTCCGGTGCTCTATACGCTCGTCTATGGCA
TCAAGCCTGGTGAAGACCAGCATGTCTAA

Protein sequence :
MNIAEYSIRHKVVSWLFTLILLIGGVVSFTRLGQLEDPEFTLKIAMVVTNYAGASPRQVEEEVTLPVEKAIQSLPYVKNV
TSISSNGLSQVQVEMKPEYRAAELKQIWDELRHKMTDLQDQLPPGAGTIQVIDDFGDVYGILLAVTGGGYSYQDMKDYAD
YLTRELVLVDGVGKVTIGGQRQEQVLVELSRSRLASLGISPDRIFGLLQTQNKVNPAGKVRVGDEYIRIYPTGEFPSVQS
MGDLLISEPGASELVYLRDVATIERGYAEVPYHLYRFNGGSALTMGISFASGVNVVDVGARVDRRLAELEYQRPAGMQLA
TVYNQPKEVDNSVSAFMLNLGEAVAIVIAVLLVFMGVRSGILMGSVLLLTILGTFIIMKVMAIDLQRISLGALIIALGML
VDNAIVVTEGILVGMKRGLSKLEASKEIVRQTVWPLLGATVIAIMAFAPIGLSEDATGEYSNTLFWVLLISLMLSWVTAI
TLVPFFADLFFNEKDVGGKNGESEDPYSGKVFVIYRRLLDRAIHHRVITLSFMSVLLVVAVVGFGFVKQAFFPPSNTPMF
LVDYWLPQGSDIRATQEAAARLEHDLLEMDSVEQVTTTIGQGAQRFMLPYMPEKSYSSYAQLIVQVSDREQIDPTLAATR
ELIRDRHLQAFAKVKRLMIGPSPAASIEARFSGPDPKELRALGVKAQAIMQADSGLESIRHDWRQQEKVIRPQFQEAQAR
RAGITREDLDNTLALNFSGRNVGLYRDGSKLLPIVARPPDDERLSADNLNDVQVWSPAYSTYIPISQVVSDFKTEWENAL
IMRRDRKRTLTVQAEPDVLGEETADQVLRRIRPAIEALELPPGYSLQWGGEYEAAKDAQAAVFGSLPMGYLFMFIITIML
FDAVRSPLVIWATVPLAIIGVTFGLLVLNSPFGFMALLGFLSLSGMLVKNGIVLVEQIKLDRERLAPFDAVVSASISRVR
PVCMAAITTILGMVPLLFDAFFESMAVVIMFGLGFATVLTLIVVPVLYTLVYGIKPGEDQHV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 0.0 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ABO_2630 YP_694350.1 AcrB/AcrD/AcrF family transporter BAC0428 Protein 0.0 60
ABO_2630 YP_694350.1 AcrB/AcrD/AcrF family transporter BAC0519 Protein 0.0 60
ABO_2630 YP_694350.1 AcrB/AcrD/AcrF family transporter BAC0526 Protein 0.0 56
ABO_2630 YP_694350.1 AcrB/AcrD/AcrF family transporter BAC0425 Protein 0.0 44