Gene Information

Name : thiC (ABO_2499)
Accession : YP_694219.1
Strain : Alcanivorax borkumensis SK2
Genome accession: NC_008260
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2833192 - 2835066 bp
Length : 1875 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
GTGCCAGACGATCAGCGCCCCATCGCCAACGCCATTGACGAATCTTGTCAGCCTATCGCCGGTTCACGAAAAATCTATGT
CACGGGGTCGCGCCCGGATATTCGTGTGCCCATGCGGGAAATCCAGCAGCATCCGACCCCTTTGGCGGACGGAAAGTTCG
AGGATAACCCACCGCTGTCGGTTTATGATACCTCTGGTCCTTATACCGACCCAGATACCTATATCGACATCCGTAAAGGG
CTGAACCCAATTCGGGATGCCTGGATTGCTGAGCGTGATGACACCGAACAGCTGGCCGGGTTGACCAGTGAGTATGGTCG
CAAGCGAGCCAATGATGTTGCCAAGGCAGGGCTACGCTTTGAGCACACTCGCATTCCTCGTCGTGCCCGTGCGGGCAAGA
ATGTTACCCAGATGCACTACGCGCGCCAGGGGATCATCACCCCGGAGATGGAATATATCGCCATCCGCGAGAATCAGCGC
TTGCGTGAACATCGCGAAGCGGGCCTGCCTGTGAACCAGCATCCCGGCCAGAGTTTTGGTGCGGCGATTCCGGCGGAAAT
TACGCCGGAATTCGTCCGTGATGAAGTGGCCCGTGGTCGAGCAGTGATTCCGGTGAATATCAACCATCCGGAAATTGAGC
CGATGATTATCGGCCGCAACTTTCTCACCAAGATCAACGCCAATATCGGCAACTCGGCGGTGACGTCCTCCATCGAGGAA
GAGGTGTCGAAGATGACCTGGGCCACCCGTTGGGGCGGCGACACGGTGATGGACCTGTCCACCGGTGACAACATTCACGA
AACCCGCGAGTGGATTCTGCGTAACTCGCCGGTGCCCATCGGTACGGTGCCGATCTATCAGGCGTTAGAAAAGGTTAACG
GCGTAGCCGAAGACCTGACGTGGGAAATTTTCCGCGACACCTTAATCGAGCAGGCGGAGCAGGGGGTGAGCTACTTCACC
ATTCACGCGGGTGTGCTGCTGCGTTATGTGCCGATGACCGCTAATCGCGTTACCGGTATCGTCTCTCGGGGTGGTTCGAT
TATGGCTAAGTGGTGCCTGGCGCACCATGAAGAAAGCTTCCTCTACACCCATTTCGAAGATATCTGCGAAATCATGAAGG
CCTACGACGTGACCTTCAGCCTGGGTGATGGTTTGCGTCCGGGTTCTTTGGCAGATGCCAACGATGAAGCCCAATTCAGC
GAACTGCGCACTTTGGGCGAGCTGACCAAAATTGCCTGGAAGCATGATGTGCAGGTGATGATCGAAGGGCCGGGCCATGT
GCCCATGCACATGATCAAAGCCAACATGGACGAGCAGCTGAAGCACTGCGGGGAAGCGCCGTTTTACACCCTTGGCCCGC
TGACCATTGATATTTCTCCGGGTTATGACCACATTTCCAGTGCCATTGGCGCGGCCATGATCGGTTGGTATGGCACTGCC
ATGCTGTGCTACGTGACGCCCAAGGAGCACCTAGGGCTGCCGAACCGTGAAGACGTGAAAGAAGGCATCATCGCCTACAA
GATTGCAGCCCATGCGGCGGATTTGGCGAAGGGTCACCCGGGAGCCCAGTTGCGCGATAATGCGCTGTCCAAGGCCCGCT
TTGAGTTCCGCTGGGAAGACCAGTTCAACCTGGGGCTGGATCCGGATCGTGCCCGCGAGTATCACGATGAGACTCTGCCA
AAGCAGGCCCACAAGGTGGCGCATTTCTGTTCCATGTGCGGGCCCAAGTTCTGTTCCATGAAGATCAGCCAAGAAGTCCG
CGAGATCTATGGTGACGGCACCGCCCAGGTGGCTCAGGCTGAAGCGGGCATGGAAGAAAAATCTAAGGAGTTTCGAGAGC
AGGGCTCCGCGCTATATCATGAGGCCCATGAGTAA

Protein sequence :
MPDDQRPIANAIDESCQPIAGSRKIYVTGSRPDIRVPMREIQQHPTPLADGKFEDNPPLSVYDTSGPYTDPDTYIDIRKG
LNPIRDAWIAERDDTEQLAGLTSEYGRKRANDVAKAGLRFEHTRIPRRARAGKNVTQMHYARQGIITPEMEYIAIRENQR
LREHREAGLPVNQHPGQSFGAAIPAEITPEFVRDEVARGRAVIPVNINHPEIEPMIIGRNFLTKINANIGNSAVTSSIEE
EVSKMTWATRWGGDTVMDLSTGDNIHETREWILRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTLIEQAEQGVSYFT
IHAGVLLRYVPMTANRVTGIVSRGGSIMAKWCLAHHEESFLYTHFEDICEIMKAYDVTFSLGDGLRPGSLADANDEAQFS
ELRTLGELTKIAWKHDVQVMIEGPGHVPMHMIKANMDEQLKHCGEAPFYTLGPLTIDISPGYDHISSAIGAAMIGWYGTA
MLCYVTPKEHLGLPNREDVKEGIIAYKIAAHAADLAKGHPGAQLRDNALSKARFEFRWEDQFNLGLDPDRAREYHDETLP
KQAHKVAHFCSMCGPKFCSMKISQEVREIYGDGTAQVAQAEAGMEEKSKEFREQGSALYHEAHE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 76
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 76
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 72