Gene Information

Name : hemC (ABO_2322)
Accession : YP_694042.1
Strain : Alcanivorax borkumensis SK2
Genome accession: NC_008260
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2649558 - 2650490 bp
Length : 933 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTCCCGCGAAATCTTGCGTATCGCTACCCGTTCCAGCCCGTTGGCTATTTGGCAGGCCGAGTATGTTCAGCAGCGCCT
GGAAAGCCTGCATGAGGGATTGCGCGTGGAGCTGGTGCGGATTAAGACTCAGGGCGACAAGATTCTCGATACCCCGCTGG
CAAAGATTGGTGGCAAAGGATTATTCGTCAAAGAGCTGGAAGAGGCGATGATGGATGGGCGCGCGGATATTGCCGTGCAT
TCCATGAAAGATGTGCCAATGGAATTGCCACCGGGTTTTGCGTTGCCAGTGATTTGTGAGCGTGAAGATCCCCGGGATGC
CTTTGTCTCCAACACGTTCGACGGCCTATCTTCGCTGCCCCATGGTGCCTGCGTGGGGACCTCCAGCCTGCGTCGCCAGG
CTCAGGTAAAAGCCAATCGCCCGGATTTGGTCGTCAACAGTCTCCGCGGTAATGTGCAGACCCGGCTGGGCAAGCTGGAT
GCGGGTAACTTCGATGCCATTATCCTTGCCGCCGCGGGCCTTAAGCGCCTGGAAATGCACGATCGCATTCGTTACGAAAT
GCCTCCGGAAGAATCGCTCCCCGCAGTGGGGCAAGGCGCCGTGGGTATCGAGTGTCGTGAGGGTGATGAGAGCACCATTG
AGTTGCTGTCACCGCTGAGTGACGTGGATACTTGGGATCGGGTGGTGGCCGAACGGGCCATGAACCGGCGCCTCGAAGGG
GGGTGTCAGGTGCCGATCGCGGGTTTTGCTCTGCTTGAAGATGGCCAGTTGTGGCTACGTGGCTTGGTGGCAGAAGAAGA
TGGTAGCCGGGTATTGCGCGCAGAAGGAACCGCTCCCCGCGGCCAAGGCGCGGAACTGGGTATCGATATTGCTGAGCAGT
TATTGGCCCAGGGCGCGGATGAAATTTTGAAGGCCTTGTACGCTCGCCAATGA

Protein sequence :
MSREILRIATRSSPLAIWQAEYVQQRLESLHEGLRVELVRIKTQGDKILDTPLAKIGGKGLFVKELEEAMMDGRADIAVH
SMKDVPMELPPGFALPVICEREDPRDAFVSNTFDGLSSLPHGACVGTSSLRRQAQVKANRPDLVVNSLRGNVQTRLGKLD
AGNFDAIILAAAGLKRLEMHDRIRYEMPPEESLPAVGQGAVGIECREGDESTIELLSPLSDVDTWDRVVAERAMNRRLEG
GCQVPIAGFALLEDGQLWLRGLVAEEDGSRVLRAEGTAPRGQGAELGIDIAEQLLAQGADEILKALYARQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-84 63
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-84 63