Gene Information

Name : fepC (SFV_0536)
Accession : YP_688099.1
Strain : Shigella flexneri 8401
Genome accession: NC_008258
Putative virulence/resistance : Virulence
Product : iron-enterobactin transporter ATP-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 566212 - 567027 bp
Length : 816 bp
Strand : -
Note : with FepBDE is involved in the transport of ferric enterobactin

DNA sequence : 
ATGACCGAATCAGTAGCCCGTTTGCGCGGCGAACAGTTAACCCTGGGATATGGCAAATATACCGTTGCGGAAAATCTGAC
TGTAGAAATTCCTGATGGTCACTTCACGGCAATTATCGGACCAAATGGCTGTGGTAAATCCACGTTACTGCGTACCTTAA
GCCGCCTGATGACGCCTGCTCACGGACATGTCTGGCTGGATGGCGAGCACATTCAACATTACGCCAGTAAAGAAGTTGCA
CGCCGGATTGGTCTGTTGGCGCAAAATGCTACCACGCCGGGCGATATCACCGTGCAGGAGCTGGTGGCGCGTGGACGTTA
TCCGCATCAACCGCTGTTTACCCGCTGGCGCAAAGAGGATGAAGAAGCGGTAACGAAAGCGATGCAGGCCACGGGAATAA
CTCATCTGGCAGATCAAAGCGTGGATACCCTTTCTGGCGGACAACGCCAGCGAGCGTGGATCGCGATGGTGCTGGCCCAG
GAAACGGCAATTATGCTGCTCGACGAACCCACGACCTGGCTGGATATCAGTCATCAGATTGATCTACTGGAACTGTTAAG
CGAACTGAACCGCGAGAAAGGCTATACCCTGGCGGCGGTGCTGCACGATCTTAATCAGGCCTGTCGTTACGCCAGCCATT
TGATTGCATTGCGGGAAGGGAAAATTGTTGCTCAGGGAGCGCCGAAGGAGATTGTCACTGCTGAACTGATTGAGCGCATT
TATGGTCTGCGATGCATGATCATTGACGATCCGGTAGCCGGAACGCCGCTTGTGGTGCCGCTCGGACGAACGGCACCTTC
AACCGCAAATAGTTAA

Protein sequence : 
MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVA
RRIGLLAQNATTPGDITVQELVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQ
ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTAELIERI
YGLRCMIIDDPVAGTPLVVPLGRTAPSTANS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 3e-59 50
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 3e-49 50
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 2e-59 49
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 2e-59 49
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 3e-59 49
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 3e-59 49
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 8e-56 47
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 8e-56 47
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-47 42
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-47 42
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-47 42
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-47 42
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-45 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fepC YP_688099.1 iron-enterobactin transporter ATP-binding protein BAC0164 Protein 2e-49 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fepC YP_688099.1 iron-enterobactin transporter ATP-binding protein VFG0925 Protein 4e-120 99
fepC YP_688099.1 iron-enterobactin transporter ATP-binding protein VFG1042 Protein 2e-49 50