Gene Information

Name : pepA (SFV_4233)
Accession : YP_691520.1
Strain : Shigella flexneri 8401
Genome accession: NC_008258
Putative virulence/resistance : Unknown
Product : leucyl aminopeptidase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0260
EC number : 3.4.11.1
Position : 4370228 - 4371739 bp
Length : 1512 bp
Strand : +
Note : catalyzes the removal of N-terminal amino acids preferably leucine from various peptides

DNA sequence :
ATGGAGTTTAGTGTAAAAAGCGGTAGCCCGGAGAAACAGCGGAGTGCCTGCATCGTCGTGGGCGTCTTCGAACCACGTCG
CCTTTCTCCGATTGCAGAACAGCTCGATAAAATCAGCGATGGGTACATCAGCGCCCTGCTACGCCGGGGCGAACTGGAAG
GAAAACCGGGGCAGACATTGTTGCTGCACCATGTTCCGAATGTACTTTCCGAGCGAATTCTCCTTATTGGTTGCGGCAAA
GAACGTGAGCTGGATGAGCGTCAGTACAAGCAGGTTATTCAGAAAACCATTAATACGCTGAATGATACTGGCTCGATGGA
AGCGGTCTGCTTTCTGACTGAACTGCACGTTAAAGGCCGTAACAACTACTGGAAAGTGCGTCAGGCTGTCGAGACAGCAA
AAGAGACGCTCTACAGTTTCGATCAGTTGAAAACGAATAAGAGCGAACCGCGTCGTCCGCTGCGTAAAATGGTGTTCAAC
GTGCCGACCCGCCGTGAACTGACCAGCGGTGAGCGCGCGATCCAGCACGGTCTGGCGATTGCCGCCGGGATAAAAGCAGC
GAAAGATCTCGGTAATATGCCGCCGAATATCTGTAACGCCGCTTATCTCGCCTCTCAGGCGCGCCAGCTGGCTGACAGCT
ACAGCAAGAATGTCATCACCCGCGTTATCGGCGAACAGCAGATGAAAGAGCTGGGAATGCACTCTTATCTGGCGGTCGGT
CAGGGTTCACAAAACGAATCGCTGATGTCGGTGATTGAGTACAAAGGCAACGCGTCGGAAGATGCACGCCCAATCGTGCT
GGTGGGTAAAGGTTTAACCTTCGACTCCGGCGGTATCTCCATCAAGCCTTCAGAAGGCATGGATGAGATGAAGTACGATA
TGTGCGGCGCGGCGGCGGTTTACGGCGTGATGCGTATGGTCGCGGAGCTGCAACTGCCGATTAACGTTATTGGCGTGCTG
GCAGGCTGTGAAAACATGCCTGGCGGGCGTGCCTATCGTCCGGGCGATGTGTTAACCACCATGTCCGGTCAAACCGTTGA
AGTGCTGAACACCGATGCCGAAGGCCGCCTGGTACTGTGCGACGTGTTAACTTACGTTGAACGTTTTGAGCCGGAAGCAG
TGATTGACGTGGCGACGCTGACCGGTGCCTGCGTGATCGCGCTGGGTCATCATATTACTGGTCTGATGGCGAACCATAAT
CCGCTGGCCCATGAACTGATTGCCGCGTCTGAACAATCCGGTGACCGCGCATGGCGCTTACCGCTGGGTGACGAGTATCA
GGAACAGCTGGAGTCCAATTTTGCCGATATGGCGAACATTGGCGGTCGTCCTGGTGGGGCGATTACCGCAGGTTGCTTCC
TGTCACGCTTTACCCGTAAGTATAACTGGGCGCACCTGGATATTGCAGGAACCGCCTGGCGTTCTGGTAAAGCAAAAGGC
GCAACCGGTCGTCCGGTAGCGTTGCTGGCACAGTTCCTGTTAAACCGCGCTGGGTTTAACGGCGAAGAGTAA

Protein sequence :
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGK
ERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVG
QGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVL
AGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHN
PLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKG
ATGRPVALLAQFLLNRAGFNGEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00295 YP_008207760.1 Leucyl aminopeptidase Not tested AbaR25 Protein 2e-90 55
BJAB0868_00299 YP_008211625.1 Leucyl aminopeptidase Not tested AbaR26 Protein 2e-90 55