Gene Information

Name : intC (SFV_3870)
Accession : YP_691185.1
Strain : Shigella flexneri 8401
Genome accession: NC_008258
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 3970404 - 3971588 bp
Length : 1185 bp
Strand : -
Note : Code: L; COG: COG0582

DNA sequence :
ATGGCATTAACCGATATCAAAGTGAAAACCGCAAAACCCAAAGACAAACCCTATAAGCTTGCTGATGGCGGCGGTATGTA
TCTACTGATTAACACTAATGGTTCTAAATACTGGCGCATGAAGTACCGCTTTGCTGGTAAAGAAAAGATGCTTTCTATTG
GCGTATACCCCGATGTAACGCTAGCCGATGCTCGCGAGAAACGCAGTGAAGCCAGGAAACTCCTCGCTGCTGGAGGCGAT
CCAGGGGAGGCAAAAAAGGAAGAAAAAATCGCGCAGCAAATGAGTCTGAAAAATACGTTCGAGGCTATTGCTCGCGAATG
GCACCAGTTAAAAGCTGATCGGTGGTCATTACGCTATCGTGATGAAATCATTGATACCTTTGAAAAAGACATTTTTCCCT
ACATTGGCAAGCGCCCTATTGCCGAAATCAAACCAATGAAGTTACTGGAAGCACTGCGTAAAATGGAAAAACGTGGAGCT
CTGGAGAAAATGCGCAAGGTCCGCCAGCGCTGTGGTGAGGTGTTCCGCTATGCAATTGTTACTGGCCGGGCAGACTATAA
CCCAGCCCCCGATCTTGCCAGTGCTTTAGCTACACCGAAAAAAGTACATTTTCCCTTTCTTACTGCTAATGAACTTCCCC
ACTTCCTCAACGATCTGGCGGGTTATACCGGAAGTATAATCACTAAGACAGCTACTCAGATCATTATGTTAACCGGCGTA
CGAACACAAGAACTGCGTTTTGCACGCTGGGAAGATATCGATTTTGAGACAAAATTGTGGGAGATCCCGGCAGAAGTAAT
GAAGATGAAGCGACCTCATATTGTGCCGCTCTCTGAGCAGGTCATTATGCTATTTAAGCAGCTTGAACCAATCTCAAAAC
ATCATCCCCTAGTCTTTATCGGTAGAAATGATCCCCGCAAACCAATTAGTAAGGAAAGCATTAACCAAGCAATTGAATTA
CTTGGATATAAGGGAAGACTCACAGGGCACGGTTTCAGACACACCATGAGTACAATTCTGCATGAACAAGGCTTTAATTC
CGCCTGGATTGAAATGCAGTTAGCTCATGTGGATAAAAATTCCATCAGGGATACCTATAATCATGCCCTGTATCTCGATG
GCCGCCGTGAAATGATGCAATGGTACGCTGATTACATTGATTCACTCTCCAGCCGGGAAAGTTAA

Protein sequence :
MALTDIKVKTAKPKDKPYKLADGGGMYLLINTNGSKYWRMKYRFAGKEKMLSIGVYPDVTLADAREKRSEARKLLAAGGD
PGEAKKEEKIAQQMSLKNTFEAIAREWHQLKADRWSLRYRDEIIDTFEKDIFPYIGKRPIAEIKPMKLLEALRKMEKRGA
LEKMRKVRQRCGEVFRYAIVTGRADYNPAPDLASALATPKKVHFPFLTANELPHFLNDLAGYTGSIITKTATQIIMLTGV
RTQELRFARWEDIDFETKLWEIPAEVMKMKRPHIVPLSEQVIMLFKQLEPISKHHPLVFIGRNDPRKPISKESINQAIEL
LGYKGRLTGHGFRHTMSTILHEQGFNSAWIEMQLAHVDKNSIRDTYNHALYLDGRREMMQWYADYIDSLSSRES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
int AAD44730.1 Int Not tested SHI-2 Protein 0.0 100
aec33 AAW51716.1 Int Not tested AGI-3 Protein 0.0 99
int CAC39282.1 integrase Not tested LPA Protein 0.0 99
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 0.0 99
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 0.0 99
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 0.0 99
int ACU09430.1 integrase Not tested LEE Protein 1e-180 96
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 2e-180 96
ECs4534 NP_312561.1 integrase Not tested LEE Protein 2e-180 96
int AAC31482.1 CP4-like integrase Not tested LEE Protein 1e-180 96
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 1e-123 62
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 5e-126 62
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 3e-75 44
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 2e-80 44
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 2e-80 44
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 2e-83 42
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 1e-83 42
int AAK16198.1 Int Not tested PAI-I AL862 Protein 1e-83 42
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 1e-83 42
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 8e-84 42
int AAL51028.1 CP4-like integrase Not tested LEE Protein 8e-84 42
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 6e-83 42
int-phe AAL60261.1 Int-phe Not tested LEE Protein 8e-84 42
int AAL51003.1 CP4-like integrase Not tested LEE Protein 6e-83 42
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 5e-83 42
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 1e-83 42
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 9e-82 42
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 9e-84 42
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 9e-84 42
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 6e-83 42
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 2e-83 42
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 5e-83 42
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 8e-84 42
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 2e-83 42
int AAK00456.1 Int Not tested SHI-1 Protein 2e-74 41
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 3e-75 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
intC YP_691185.1 integrase VFG0598 Protein 0.0 99
intC YP_691185.1 integrase VFG0783 Protein 0.0 96
intC YP_691185.1 integrase VFG0626 Protein 4e-84 42
intC YP_691185.1 integrase VFG1693 Protein 8e-84 42
intC YP_691185.1 integrase VFG1536 Protein 2e-75 41