Gene Information

Name : ribD (SFV_0379)
Accession : YP_687956.1
Strain : Shigella flexneri 8401
Genome accession: NC_008258
Putative virulence/resistance : Unknown
Product : bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0117
EC number : 1.1.1.193
Position : 397069 - 398154 bp
Length : 1086 bp
Strand : +
Note : riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine a

DNA sequence :
ATGGCGCGGGCGCTAAAGCTGGCGCAACGAGGACGTTTTACCACCCACCCCAACCCGAATGTCGGGTGCGTCATTGTCAA
AGATGGCGAAATTGTCGGTGAAGGTTACCACCAACGAGCGGGTGAACCACATGCCGAAGTACACGCGTTGCGTATGGCGG
GTGAAAAAGCCAAAGGCGCAACGGCGTATGTGACACTCGAACCCTGTAGCCATCATGGCCGTACGCCACCGTGCTGTGAC
GCACTCATCGCCGCTGGCGTAGCGCGCGTGGTCGCAGCGATGCAAGATCCTAACCCGCAGGTCGCTGGGCGTGGACTTTA
CCGTCTGCAACAGGCTGGCATTGACGTCAGCCACGGGCTGATGATGAGTGAAGCCGAGCAATTGAATAAAGGCTTTCTCA
AGCGGATGCGCACCGGCTTTCCTTATATTCAGTTAAAACTTGGCGCATCGCTTGATGGCCGCACGGCGATGGCGAGCGGC
GAAAGCCAGTGGATCACTTCGCCTCAGGCGCGGCGCGACGTACAACGACAGCGCGCACAAAGTCATGCCATTTTAACCAG
CAGCGCCACGGTGCTGGCGGATGATCCAGCCTTAACAGTGCGTTGGTCTGAACTGGATGAACAAACTCAGGCGCTCTACC
CGCAACAAAATCTCCGCCAGCCAGTACGTATTGTGATTGATAGCCAAAATCGCGTGACGCCGGAACATCGCATTGTGCAG
CAGCCCGGCGAAACCTGGTTCGCGCGTACGCAGGAAGATTCTCGTGAGTGGCCGGAAACGGTGCGTACCTTGCTGATTCC
AGAGCATAAAGGTCATCTGGATCTGGTTGTACTGATGATGCAACTGGGTAAACAGCAGATTAACAGCATCTGGGTGGAAG
CGGGGCCAACGCTCGCTGGCGTATTGCTACAGGCGGGTTTAGTCGATGAGCTGATTGTCTATATCGCACCTAAACTATTA
GGCAGCGACGCCCGTGGATTATGCTCGCTGCCAGGGCTTGAGAAATTAGCCGACGCCCCCCAATTTAAATTCAAAGAGAT
ACGTCATGTAGGCCCGGATGTTTGCCTGCATTTAGTGGGTGCATGA

Protein sequence :
MARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQRAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCD
ALIAAGVARVVAAMQDPNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGRTAMASG
ESQWITSPQARRDVQRQRAQSHAILTSSATVLADDPALTVRWSELDEQTQALYPQQNLRQPVRIVIDSQNRVTPEHRIVQ
QPGETWFARTQEDSREWPETVRTLLIPEHKGHLDLVVLMMQLGKQQINSIWVEAGPTLAGVLLQAGLVDELIVYIAPKLL
GSDARGLCSLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00289 YP_008207754.1 Pyrimidine deaminase Not tested AbaR25 Protein 1e-59 47
BJAB0868_00293 YP_008211619.1 Pyrimidine deaminase Not tested AbaR26 Protein 1e-59 47