Gene Information

Name : cvrA; nhaP2; ycgO (SFV_1199)
Accession : YP_688711.1
Strain : Shigella flexneri 8401
Genome accession: NC_008258
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 1242515 - 1244251 bp
Length : 1737 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGGATGCCACAACAATAATTAGCCTTTTCATCTTAGGATCCATCCTTGTCACCAGCAGTATATTACTTAGTTCATTTTC
TTCCCGTCTTGGCATTCCTATTCTGGTTATTTTTCTGGCGATCGGCATGCTGGCGGGAGTCGATGGCGTCGGCGGTATCC
CGTTTGATAATTACCCCTTCGCCTACATGGTAAGTAACCTGGCGCTGGCGATTATTTTGCTCGACGGCGGGATGCGCACT
CAGGCCAGTTCCTTTCGTGTGGCGTTAGGACCGGCGCTGTCGCTGGCGACGCTGGGCGTACTTATCACCTCTGGTTTAAC
CGGCATGATGGCGGCGTGGCTGTTTAATCTTGATTTGATTGAAGGCTTATTAATCGGCGCTATCGTCGGCTCCACCGATG
CTGCAGCGGTCTTTTCTCTGCTGGGTGGTAAGGGGCTTAACGAACGTGTTGGCTCGACGCTGGAAATTGAATCCGGCAGT
AATGATCCAATGGCGGTCTTTCTGACGATTACCCTGATTGCAATGATCCAGCAGCATGAAAGCAGTGTCAGTTGGATGTT
CGTGGTCGATATTCTGCAGCAATTTGGCCTCGGGATTGTCATCGGTCTTGGCGGTGGTTATTTACTGCTGCAAATGATTA
ATCGCATCGCCCTGCCTGCCGGATTATATCCATTGCTGGCATTAAGCGGCGGTATTTTAATTTTTGCTTTAACCACGGCG
CTGGAAGGCAGCGGTATTCTGGCTGTTTATCTGTGCGGTTTTCTGCTGGGTAATCGGCCGATTCGCAACCGCTACGGCAT
CCTGCAAAATTTCGACGGCCTCGCCTGGCTGGCGCAAATCGCCATGTTCCTGGTGCTGGGGCTATTGGTTAACCCAAGCG
ATCTGCTGCCTATTGCCATTCCGGCGCTCATTTTGTCGGCATGGATGATATTCTTCGCCCGTCCCCTTTCGGTATTTGCT
GGATTGCTCCCTTTCCGCGGTTTCAATCTGCGTGAGCGCGTGTTTATCAGCTGGGTGGGATTACGCGGCGCGGTGCCAAT
CATCCTAGCCGTGTTCCCGATGATGGCGGGGCTGGAGAATGCGCGACTGTTCTTTAATGTCGCCTTCTTTGTGGTTCTGG
TTTCACTGCTCTTGCAGGGAACATCACTCTCGTGGGCGGCGAAAAAAGCCAAAGTGGTGGTTCCGCCCGTCGGACGTCCG
GTGTCACGCGTTGGCCTGGATATTCATCCGGAAAATCCGTGGGAGCAGTTTGTTTATCAATTGAGTGCTGATAAATGGTG
TGTAGGTGCGGCACTGCGCGATTTGCATATGCCAAAAGAGACGCGTATTGCAGCCCTGTTTCGTGATAACCAGTTGCTTC
ATCCTACCGGCAGCACCCGACTGCGCGAAGGCGATGTATTGTGTGTAATTGGTCGGGAACGCGATCTCCCGGCGCTCGGT
AAACTGTTCAGCCAGTCGCCACCGGTCGCGCTGGATCAACGCTTCTTTGGTGACTTCATTCTCGAAGCCAGCGCCAAATA
TGCTGATGTTGCGCTGATATATGGCCTGGAAGACGGGCGAGAATATCGTGATAAACAGCAAACGCTGGGTGAAATTGTCC
AGCAGTTGCTAGGCGCGGCACCGGTTGTCGGTGACCAGGTAGAGTTTGCCGGGATGATCTGGACGGTGGCCGAGAAAGAA
GATAATGAAGTGTTGAAGATTGGCGTTCGGGTGGCTGAAGAGGAAGCTGAATCTTAA

Protein sequence :
MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRT
QASSFRVALGPALSLATLGVLITSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
NDPMAVFLTITLIAMIQQHESSVSWMFVVDILQQFGLGIVIGLGGGYLLLQMINRIALPAGLYPLLALSGGILIFALTTA
LEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFA
GLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPVGRP
VSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDNQLLHPTGSTRLREGDVLCVIGRERDLPALG
KLFSQSPPVALDQRFFGDFILEASAKYADVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKE
DNEVLKIGVRVAEEEAES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 0.0 99
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 0.0 99