Gene Information

Name : guaA (CHU_0934)
Accession : YP_677553.1
Strain : Cytophaga hutchinsonii ATCC 33406
Genome accession: NC_008255
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1070660 - 1072189 bp
Length : 1530 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACTGAAAAAATATTAATCCTGGATTTTGGATCTCAATACACTCAGCTGATTGCCAGAAGAGTAAGAGAATTAAATGT
TTATTGTGAAATTCACCCATACAATAAAGCACCACAAATAGATGGCACGGTTAAAGGAGTAATTCTTTCCGGCAGTCCTT
GTTCAGTTAGAGAAGAAAACGCACCGGATATTGACCTATCTTTATACAGAGAAAAATTACCCCTTTTAGGTGTTTGTTAT
GGAGCACAATTGATTGCCCATAAATCAGGCGGAACGGTTCAGCCATCTTCTATCCGTGAATACGGAAGAGCACGGTTGAA
TAACGTACACACTTCAGATGATTTATTTAAAGAAATTGTACCGGATTCTCAGGTTTGGATGTCACATGGTGATACAATCG
TAGAAATTCCTTCCAATTTTGAAATATTAAGCAGCACCGAAACTGTTCGTGTAGCAGCCTACAAAGTAAAAGGAGAAGAT
ACATTCGGCATTCAGTTTCACCCGGAGGTTACACACTCCTTACAAGGCAAAGAATTATTAAGAAACTTTGTTGTACATAT
TTGCGGTTGTTCACAAGATTGGACACCGGATGCATTTGTTGAAACAACTATCAGTGAACTGAAAGCTAAAATCGGTACAG
ACAAAGTTGTACTTGGTTTGTCAGGCGGCGTAGATTCATCTGTTGCAGCAGTATTGATACATAAAGCGATCGGGCCAAAC
TTAACATGTATTTTTGTTGATAATGGTTTGCTTCGTAAAAACGAATACGAGGAAGTATTGAATTCATATAAACATATGGG
TTTAAATGTGATCGGTGTTGATGCAAAAAAACAATTTTACAAATCGCTTGAAGGCTTGAGTGATCCGGAAGCAAAACGGA
AAGCGATCGGTAAAGAATTTATTGAAGTGTTCGACCAGGAGTCTCACAAAATTGCAGACGTAAAATGGCTGGGACAGGGA
ACAATTTATCCGGACATTATCGAATCTGTTTCTGTTAAAGGCCCTTCAGCTACCATCAAGTCTCACCACAATGTAGGTGG
TTTGCCTGAAAAGATGAAATTGAAAATTGTTGAACCGCTGAACACGTTGTTTAAAGACGAAGTGAGAAGAGTAGGTAAGA
CATTAGGCATCGATGATATCATTTTAAAAAGACATCCATTCCCTGGACCTGGTTTGGCCATACGTATCCTTGGCGACATT
ACAGCAGAAAAAGTAGCTGTACTGCAGGAAGTGGATTATATTTTCATTTCACGTCTGAAAGAAAAAGGTTTATATGATCA
GGTTTGGCAGGCAGGCGCTATATTGCTTCCTGTAAAATCTGTCGGCGTAATGGGAGATGAAAGAACCTATGAAAATGTTG
TAGCATTGCGTGCTGTAAGCAGCATGGATGGTATGACAGCAGACTGGATTCATTTACCATACGATTTTCTGGCAGATATT
TCAAATGAAATCATAAACCGTGTAAAAGGTGTGAACCGGGTTGTGTATGACATCAGCTCTAAACCGCCTGCAACCATTGA
ATGGGAATAA

Protein sequence :
MTEKILILDFGSQYTQLIARRVRELNVYCEIHPYNKAPQIDGTVKGVILSGSPCSVREENAPDIDLSLYREKLPLLGVCY
GAQLIAHKSGGTVQPSSIREYGRARLNNVHTSDDLFKEIVPDSQVWMSHGDTIVEIPSNFEILSSTETVRVAAYKVKGED
TFGIQFHPEVTHSLQGKELLRNFVVHICGCSQDWTPDAFVETTISELKAKIGTDKVVLGLSGGVDSSVAAVLIHKAIGPN
LTCIFVDNGLLRKNEYEEVLNSYKHMGLNVIGVDAKKQFYKSLEGLSDPEAKRKAIGKEFIEVFDQESHKIADVKWLGQG
TIYPDIIESVSVKGPSATIKSHHNVGGLPEKMKLKIVEPLNTLFKDEVRRVGKTLGIDDIILKRHPFPGPGLAIRILGDI
TAEKVAVLQEVDYIFISRLKEKGLYDQVWQAGAILLPVKSVGVMGDERTYENVVALRAVSSMDGMTADWIHLPYDFLADI
SNEIINRVKGVNRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-122 50
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-122 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-122 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-110 46