Gene Information

Name : Meso_3944 (Meso_3944)
Accession : YP_676476.1
Strain : Chelativorans sp. BNC1
Genome accession: NC_008254
Putative virulence/resistance : Resistance
Product : Bcr/CflA subfamily drug resistance transporter
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 4247016 - 4248221 bp
Length : 1206 bp
Strand : -
Note : TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sme:SMc00744 putative transport protein transmembrane

DNA sequence :
ATGTCCAGAAATATCCGGCTGTGGACCTACAGCCTGCCTGTCGCATTGATGCTGCTGGCACCCTTCAACATCCTTGCCTC
GCTTGGCATGGACATTTACCTGCCTGCCATTCCCGCAATGCCAGGAATCCTCGGCACCACACCCAATGTGGTGCAACTAA
CGCTCACCCTCTACATGATTATGCTCGGGGTAGGACAGATCCTCTTCGGGCCTCTTTCGGACCGTCTCGGCCGCAGGCCC
GTCCTGATCGGCGGGGCGATCCTCTTCGCCACTGCTTCCTTTGCTCTTGCGGCCACATCCTCGGCCGGGCTGTTCCTGCT
TCTCCGGTTGGCTCAGGCCACGGGCGCGGCTGCGGTGCTGGTTGCCCTTTTCGCCACCATCCGCGACGTCTATGCCGAGC
GTCCAGAAAGCGCCGTCATATACAGCCTCATGAATGCCATGCTGGCATTCGTGCCTGCGGTCGGTCCCATCGCCGGCGCG
CTGATCATGGGGATCTGGGGATGGCGCGCCATCTTCCTTGCGCTGGGCATTCCGGCGCTCATCGTGCTCACCCTCATGCT
TCCCGCCTGGCACGAGACCCGGCAGGCGAAGGGAGGACAGGATAGCGCGGGTTTTAGGCCGGTGCTCAGAAGCCCAGCCT
TTTGGACCTATACCATCGGCTTCGGAACTGCCATGGGCACATTCTTCGTGTTCTTCTCTACCGCCCCTCGCGTTCTGATC
GATGGAGCAGGCTTTTCCGAGCTCGATTTCAGCTTCGCTTTTGCAAGCGTGGCCATCGCCATGATTATTACCACGCGGTT
CGCCAAGAGCTTCGTGGCGCGATGGGGAATTCCGGGCACCCTGATGCGCGGCATGGTGATGTTGATCCTGGGGGCGTTCC
TGCTCGCGATCGGCCAGTTGTTCCTCGCCCCGTCCTTTTGGTCCCTTGTCGTGCCCATGTGGCTGATTGCGATCGGCATC
GTCTTTACGACCGCCGTCACCGCTAATGGCGCATTGCAGGAGTTCGGAGAAACTGCGGGAATGGCGGTCGCCCTGCATTT
CTGTATCCAGAGCCTCCTTGTCGGCATTGTCGGCACGGGATTTGTGATCATGCTGGATGGCAGCACCGCATGGCCTCTGA
TCACCAACGCGGCCGGCATGGCGGCGGTCACTTTGATCGCGCTCTTTTGGCTCGGCGGCCGCAATTTGCATCCGCAAACC
GCGTGA

Protein sequence :
MSRNIRLWTYSLPVALMLLAPFNILASLGMDIYLPAIPAMPGILGTTPNVVQLTLTLYMIMLGVGQILFGPLSDRLGRRP
VLIGGAILFATASFALAATSSAGLFLLLRLAQATGAAAVLVALFATIRDVYAERPESAVIYSLMNAMLAFVPAVGPIAGA
LIMGIWGWRAIFLALGIPALIVLTLMLPAWHETRQAKGGQDSAGFRPVLRSPAFWTYTIGFGTAMGTFFVFFSTAPRVLI
DGAGFSELDFSFAFASVAIAMIITTRFAKSFVARWGIPGTLMRGMVMLILGAFLLAIGQLFLAPSFWSLVVPMWLIAIGI
VFTTAVTANGALQEFGETAGMAVALHFCIQSLLVGIVGTGFVIMLDGSTAWPLITNAAGMAAVTLIALFWLGGRNLHPQT
A

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 4e-95 61
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 4e-97 59
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 4e-97 59
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 4e-97 59
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 1e-100 59
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 1e-100 59
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 1e-69 49
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 2e-69 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Meso_3944 YP_676476.1 Bcr/CflA subfamily drug resistance transporter AF294653.1.gene4.p01 Protein 2e-69 49
Meso_3944 YP_676476.1 Bcr/CflA subfamily drug resistance transporter DQ984668.gene.p01 Protein 8e-70 49
Meso_3944 YP_676476.1 Bcr/CflA subfamily drug resistance transporter AF156486.gene.p01 Protein 8e-69 49
Meso_3944 YP_676476.1 Bcr/CflA subfamily drug resistance transporter DQ522237.1.gene4.p01 Protein 8e-70 49
Meso_3944 YP_676476.1 Bcr/CflA subfamily drug resistance transporter NC_010410.6003586.p0 Protein 8e-70 49