Gene Information

Name : cadB (ECP_0328)
Accession : YP_668261.1
Strain : Escherichia coli 536
Genome accession: NC_008253
Putative virulence/resistance : Virulence
Product : lysine/cadaverine antiporter
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0531
EC number : -
Position : 348513 - 349823 bp
Length : 1311 bp
Strand : -
Note : probable cadaverine/lysine antiporter; antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein

DNA sequence :
ATGAGTGGTCCTAAAAAAATAGGATTAATAACATGTATTGCAGTTGTCGCTGGAAATATGATGGGAAGTGGTATTGCGCT
TCTTCCTGCAAGTCTGGCGAAAATAGGTTCTGTCGCTATATGGGGATGGATTATTGCGGCAATTGGTGCATTATCTCTGG
CATATGTTTTTGCTCGTCTGGCAACTAATAACCCACAAACAGGTGGGCCTATTGCGTATGCTGGAGAAGTTGCTCCAATA
TTCGGGCATCAGACATCCATTCTTTATTATCATGCAAACTGGATTGGTAATTTAGCAATAGCTATTACTGCAGTGGCATA
TTTATCAGTATTTTTCCCTGTTCTGAATAATCCTGTTCCGGCAGCGATTACCAGTATTGCCATGGTATGGTTATTTACGT
TTGTGAACTTGCTGGGCGGGGCATGGGTCAGTCGGTTGACATCAATTGGACTTGTGCTTGTTCTTATACCTGTAGTTGGA
ACGGCATTATTCGGTTGGGGATCATTCGATATTGAAGTTTATCGCCAGAACTGGATGGCTCAGCCAGATGGAAATGTCCA
CCAGGCTGTTATTAATTCTGTTCTTCTTTGCTTGTGGGCATTTGTTGGTGTCGAATCTGCGGCAGTTAGTTCAGATCTTG
TCCATAATCCTTCCCGAACAGTTCCATTGGCAACGCTGGGGGGAACTGCACTTGCAGGAATAGTTTATATTGCGGCCTCC
CAAGTTATTGCAGGCATGTTTCCGAACGAAGTCGTGGCAAATTCAGGAGCACCTTTTGCTTTAAGTGCATCCAGAATTGT
CGGGGACTGGGCGGCTCCATTTGTATCGGCATTTACGGCTATTGCATGTCTGACATCTCTGGGCTCCTGGATGATGCTGG
TTGGACAGGCAGGACGTCGTGCAGCAATGGATGGTAACTTCCCGGCTGTATTTGGAGAAACAGACAATAATGGTGTACCC
AAGAAAGGGTTGCTCATTGCATCAACGATGATGAGCATTTTGATGGTATTACTGACTATTCTCAGTGCCAGTGGTTCTAA
CGCTGCGGATTTATTTACTCAATTAACAAGCATTGCTGTTTTGTTAACTATGTTCCCATATTTTTACTCGGCTATTGACC
TTATTCGTTTTGAAAGTGCAACTTCAAAAAGTATTTTGAGTCTGATCGCTTCAGCGTTTGCTATGTTGTTCTGTTTTGCT
GCGCTGGCTGGTGCAGAGCATTATGAAATAACTGCAACAATTATTATTTCATTATTAATATTCGCTTTCTACGCAAGAAA
GCTGGGTGGCATTCAGCACAAAAATATTTAA

Protein sequence :
MSGPKKIGLITCIAVVAGNMMGSGIALLPASLAKIGSVAIWGWIIAAIGALSLAYVFARLATNNPQTGGPIAYAGEVAPI
FGHQTSILYYHANWIGNLAIAITAVAYLSVFFPVLNNPVPAAITSIAMVWLFTFVNLLGGAWVSRLTSIGLVLVLIPVVG
TALFGWGSFDIEVYRQNWMAQPDGNVHQAVINSVLLCLWAFVGVESAAVSSDLVHNPSRTVPLATLGGTALAGIVYIAAS
QVIAGMFPNEVVANSGAPFALSASRIVGDWAAPFVSAFTAIACLTSLGSWMMLVGQAGRRAAMDGNFPAVFGETDNNGVP
KKGLLIASTMMSILMVLLTILSASGSNAADLFTQLTSIAVLLTMFPYFYSAIDLIRFESATSKSILSLIASAFAMLFCFA
ALAGAEHYEITATIIISLLIFAFYARKLGGIQHKNI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66196.1 putative lysin/cadaverin transporter Virulence PAI III 536 Protein 3e-168 100
cadB NP_756989.1 lysine/cadaverine antiporter Not tested PAI II CFT073 Protein 1e-122 68
cadB AAL67382.1 cadaverine/lysine antiporter Not tested PAI II CFT073 Protein 9e-123 68

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadB YP_668261.1 lysine/cadaverine antiporter VFG1671 Protein 2e-168 100