Gene Information

Name : nrdF (ECP_2641)
Accession : YP_670531.1
Strain : Escherichia coli 536
Genome accession: NC_008253
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 2780777 - 2781736 bp
Length : 960 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGAAACTCTCACGTATCAGCGCCATCAACTGGAACAAGATATCTGACGATAAAGATCTGGAGGTGTGGAATCGCCTGAC
CAGCAATTTCTGGCTACCAGAAAAGGTGCCACTGTCGAACGATATTCCTGCATGGCAGACATTAAGTGTCGTAGAACAAC
AACTAACAATGCGCGTTTTTACTGGCCTGACGCTGCTCGACACGCTGCAAAATGTTATCGGCGCGCCCTCGCTGATGCCC
GATGCACTCACCCCCCATGAAGAGGCGGTATTATCAAATATCAGCTTTATGGAAGCGGTTCATGCCCGCTCTTACAGTTC
AATTTTCTCGACGCTGTGCCAGACCAAAGATGTCGATGCCGCCTACGCCTGGAGTGAAGAAAACGCGCCGTTGCAGCGAA
AAGCACAGATTATTCAGCAACATTATCGCGGTGATGATCCGCTGAAAAAGAAAATCACCAGTGTGTTTCTTGAATCTTTT
TTGTTCTATTCCGGTTTCTGGCTGCCGATGTATTTTTCCAGCCGCGGAAAGCTAACCAATACCGCAGACCTGATCCGTCT
GATTATCCGGGATGAAGCAGTCCACGGTTACTACATCGGCTATAAATATCAGAAAAACCTGGAAAAGATCTCCCAGGAAC
AGCGTGAAGAGTTGAAGAGTTTCGCCTTCGATTTGTTGCTGGAACTCTATGACAACGAGTTGCAATACACCGATGAGCTG
TACGCCGAAACCCCGTGGTCTGACGATGTAAAAGCGTTTCTCTGTTACAACGCCAATAAGGCGTTGATGAATCTGGGCTA
CGAACCGCTATTTCCCGCAGAAATGGCGGAAGTGAATCCGGCAATCCTCGCCGCACTTTCGCCGAATGCCGATGAAAATC
ACGATTTCTTTTCCGGTTCAGGCTCTTCATATGTGATGGGAAAAGCGGTCGAAACAGAAGATGAAGACTGGAATTTCTGA

Protein sequence :
MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPAWQTLSVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMP
DALTPHEEAVLSNISFMEAVHARSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKITSVFLESF
LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNLEKISQEQREELKSFAFDLLLELYDNELQYTDEL
YAETPWSDDVKAFLCYNANKALMNLGYEPLFPAEMAEVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEDEDWNF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 2e-105 67