Gene Information

Name : ECP_1514 (ECP_1514)
Accession : YP_669422.1
Strain : Escherichia coli 536
Genome accession: NC_008253
Putative virulence/resistance : Resistance
Product : DNA-binding transcriptional activator MarA
Function : -
COG functional category : K : Transcription
COG ID : COG2207
EC number : -
Position : 1564508 - 1564891 bp
Length : 384 bp
Strand : +
Note : transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF

DNA sequence :
ATGTCCAGACGCAATACTGACGCTATTACCATTCATAGCATTTTGGACTGGATCGAGGACAACCTGGAATCGCCACTTTC
ACTGGAGAAAGTGTCAGAGCGTTCGGGTTACTCCAAATGGCACCTGCAACGGATGTTTAAAAAAGAAACCGGTCATTCAT
TAGGTCAATACATCCGTAGCCGTAAGATGACGGAAATCGCGCAAAAGCTGAAGGAAAGTAACGAGCCGATACTCTATCTG
GCAGAACGATATGGCTTTGAGTCCCAACAAACTCTGACCCGAACCTTCAAAAATTACTTTGATGTTCCGCCGCATAAATA
CCGGATGACCAATATGCAAGGTGAATCGCGTTTTTTACATCCATTAAATCATTACAACAACTAG

Protein sequence :
MSRRNTDAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQRMFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYL
AERYGFESQQTLTRTFKNYFDVPPHKYRMTNMQGESRFLHPLNHYNN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetD AAL08447.1 putative transcriptional regulator TetD Not tested SRL Protein 3e-21 44
tetD AEA34665.1 tetracycline resistance protein D Not tested Not named Protein 3e-21 44
soxS YP_219131.1 DNA-binding transcriptional regulator SoxS Not tested SPI-4 Protein 1e-19 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA NC_002695.1.917339.p Protein 1e-56 99
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA BAC0560 Protein 1e-56 99
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA CP000034.1.gene1596. Protein 2e-56 99
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA CP001138.1.gene1637. Protein 2e-53 96
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA CP001918.1.gene2033. Protein 2e-52 93
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA CP000647.1.gene1624. Protein 1e-52 93
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA NC_010558.1.6276025. Protein 2e-21 44
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA CP001138.1.gene612.p Protein 7e-23 43
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA CP000034.1.gene4505. Protein 3e-19 42
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA BAC0371 Protein 1e-19 42
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA CP001138.1.gene4488. Protein 4e-20 42
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA NC_002695.1.914293.p Protein 1e-19 42
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA CP001918.1.gene327.p Protein 3e-20 42
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA CP000647.1.gene4499. Protein 8e-20 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA VFG1038 Protein 1e-21 44
ECP_1514 YP_669422.1 DNA-binding transcriptional activator MarA VFG0585 Protein 4e-20 42