Gene Information

Name : umuC (ECP_1227)
Accession : YP_669139.1
Strain : Escherichia coli 536
Genome accession: NC_008253
Putative virulence/resistance : Unknown
Product : DNA polymerase V subunit UmuC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0389
EC number : 2.7.7.7
Position : 1251657 - 1252925 bp
Length : 1269 bp
Strand : +
Note : binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization

DNA sequence :
ATGTTTGCCCTCTGTGATGTAAACGCGTTTTATGCCAGCTGTGAGACGGTGTTTCGCCCTGATTTATGGGGTAAACCGGT
GGTTGTGCTATCGAATAATGACGGTTGCGTTATCGCCCGAAACGCTGAGGCAAAGGCGCTGGGCGTTAAAATGGGCGATC
TCTGGTTCAAACAAAAAGATCTGTTTCGTCGCTGTGGCGTGGTTTGCTTTAGCAGCAATTATGAGCTTTACGCAGACATG
AGTAATCGGGTGATGTCGACGCTGGAAGAACTATCGCCCCGCGTCGAGATTTACAGTATTGATGAGGCATTCTGCGATCT
GACAGGTGTGCATAATTGTCGCGATCTGACTGATTTTGGCAGAGAAATTCGCGCAATGGTGCTACAACGTACCCATCTTA
CTGTTGGTGTGGGGATCGCCCAGACCAAAACGCTGGCTAAGCTTGCCAATCATGCGGCAAAAAAATGGCAGCGGCAGACG
GGCGGGGTGGTGGATTTATCAAATCTGGAACGCCAGCGTAAATTAATGTCTGCTCTCCCCGTGGATGAAGTCTGGGGGAT
TGGACGGCGGATCAGCAAAAAACTGGACGCGATGGGGATCAAAACCGTTCTCGATTTGGCGGATTCAGATATCCGGTTTA
TCCGTAAACATTTTAATGTCGTGCTCGAAAGAACGGTGCGTGAACTGCGCGGTGAACCCTGTTTGCAACTGGAAGAGTTT
GCACCGACGAAGCAGGAAATTATCTGTTCCCGCTCGTTTGGTGAACGCATCACGGATTATCCGTCGATGCGGCAGGCCAT
TTGTAGTTACGCTGCCCGGGCGGCGGAAAAACTTCGCAGCGAGCATCAATATTGTCGGTTTATCTCCACGTTTATTAAGA
CGTCACCATTTGCGTTCAATGAACCTTATTACGGCAATAGCGCATCGGTAAAACTGCTGACGCCCACTCAGGACAGCAGG
GATATCATTAACGCCGCTACGCGATCTCTGGATGCCATCTGGCAAGCGGGCCATCGCTACCAAAAAGCGGGCGTGATGCT
GGGGGATTTCTTCAGTCAGGGAGTCGCGCAGCTCAATTTATTCGATGACAACGCACCGCGCCCCGGGAGTGAGCAATTGA
TGGCGGTAATGGATACGCTGAATGCTAAAGAGGGCAGAGGAACACTCTATTTTGCCGGGCAGGGGATCCAGCAACAATGG
CAGATGAAGCGTGCCATGCTTTCACCATGTTATACAACGCGAAGTTCTGATTTACTGCGGGTCAAATAA

Protein sequence :
MFALCDVNAFYASCETVFRPDLWGKPVVVLSNNDGCVIARNAEAKALGVKMGDLWFKQKDLFRRCGVVCFSSNYELYADM
SNRVMSTLEELSPRVEIYSIDEAFCDLTGVHNCRDLTDFGREIRAMVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
GGVVDLSNLERQRKLMSALPVDEVWGIGRRISKKLDAMGIKTVLDLADSDIRFIRKHFNVVLERTVRELRGEPCLQLEEF
APTKQEIICSRSFGERITDYPSMRQAICSYAARAAEKLRSEHQYCRFISTFIKTSPFAFNEPYYGNSASVKLLTPTQDSR
DIINAATRSLDAIWQAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMAVMDTLNAKEGRGTLYFAGQGIQQQW
QMKRAMLSPCYTTRSSDLLRVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
samB NP_458681.1 UV protection protein Not tested SPI-7 Protein 2e-125 63
umuC NP_807889.1 DNA polymerase V subunit UmuC Not tested SPI-7 Protein 2e-125 63
rulB CAI36137.1 nucleotidyltransferase/DNA polymerase Not tested PPHGI-1 Protein 1e-89 50
unnamed ABR13403.1 DNA-directed DNA polymerase Not tested PAGI-5 Protein 1e-74 49