Gene Information

Name : trxB (FTF0489c)
Accession : YP_666659.1
Strain : Francisella tularensis FSC 198
Genome accession: NC_008245
Putative virulence/resistance : Unknown
Product : thioredoxin reductase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0492
EC number : 1.8.1.9
Position : 508990 - 509940 bp
Length : 951 bp
Strand : -
Note : Similar to Q8ZGC9 Thioredoxin reductase from Yersinia pestis (320 aa). FASTA: opt: 1525 Z-score: 1798.2 E(): 2.9e-92 Smith-Waterman score: 1525; 70.927 identity in 313 aa overlap

DNA sequence :
ATGGCAAATCATCATAAACTAATAATTTTAGGATCTGGGCCTGCTGGCTATACTGCAGCAATATATGCAGCACGTGCAAA
CTTAAAGCCAGTAATTATCACTGGTATGCAACCAGGAGGTCAACTTACGACTACTACCGATGTATATAACTGGCCTGGTG
AGCCTGATGGTATCATGGGTCCTGAGCTTATGGAAAAACTACAAAAACAAGCAGAAAGATTCGATACACAAATAGTCTAT
GACACTATCAATGCTGTAGATTTACAAAATAAACCTTTTAAACTAGTTGGTGAAGTTGAGCAATATACATGTGATACTCT
AATTATAGCAACTGGTGCTACTGCTAAATATCTAGGTTTAGAGTCAGAAGAGAAGTTTATGGGTAAAGGTGTCTCTGCTT
GTGCTACTTGTGATGGCTTCTTTTACAAAAATAAAGACGTTGCAGTAGTTGGTGGTGGCAACACTGCTGTTGAAGAAGCA
TTATTTTTATCCAATATTGCTAAATCTGTAACTTTAATCCACCGTAGAGATACATTAAGGTCTGAAAAAATTCTTATCGA
CAAGCTAATGGAAAAAGCTCAACATGGTAATATAAATATCATTTGGAACACTACTTTAGAAGAAGTTCTTGGCGATGATA
TGGGAGTTAATGCTCTGCGTATCAAAAATATCAAAACTAATGAAGAGTCTCAAATGGGTGTCGCTGGTGTTTTTATTGCT
ATTGGCCATACACCAAATACTAGTATTTTTGCTGGTCAGCTTGAAATGGAAAATGGCTATATTAAGGTGAAATCAGGTCT
AGCTGGCGATGCTACTCAAACAAATATCAAAGGGGTATTTGCAGCTGGTGATGTAGCTGATCATGTTTATAAACAAGCAG
TAACATCTGCAGGTACTGGCTGTATGGCTGCACTAGATGCTGAGAAGTATTTAGATAATTTAGATCAATAA

Protein sequence :
MANHHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTTDVYNWPGEPDGIMGPELMEKLQKQAERFDTQIVY
DTINAVDLQNKPFKLVGEVEQYTCDTLIIATGATAKYLGLESEEKFMGKGVSACATCDGFFYKNKDVAVVGGGNTAVEEA
LFLSNIAKSVTLIHRRDTLRSEKILIDKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQMGVAGVFIA
IGHTPNTSIFAGQLEMENGYIKVKSGLAGDATQTNIKGVFAAGDVADHVYKQAVTSAGTGCMAALDAEKYLDNLDQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
trxB AFC76431.1 TrxB Not tested AbaR5 Protein 2e-101 67
trxB CAJ77014.1 thioredoxin reductase Not tested AbaR1 Protein 1e-101 67