Gene Information

Name : hemC (FTF0259)
Accession : YP_666443.1
Strain : Francisella tularensis FSC 198
Genome accession: NC_008245
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 276059 - 276961 bp
Length : 903 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAACAAATAACTATAGCTAGTCGAGAAAGTAAACTAGCATTATGGCAGACAAATTTTGTCAAAAATCGTATCCAATT
AGAGCTAAACATTCCTTGTGAAATAAGTACTATGAAAACACAGGGAGATATTATTTTGGATCAACCGCTAAACAAAATTG
GTGGTAAAGCACTATTTATGAAAGAGCTAGAAGTAGCAATGCTTAGTAATAAGGCTGATATTGCTGTACATTCTCTTAAA
GATGTTCCTTACCAATTACCGCAAGGTTTTTGTTTAGCAGGTTTTATGCCAAGAGAAGATCCTCGAGATGCTTTTGTATC
AAATAAATATAATTCTATTGATGATTTACCTAAAGGAGCTGTTGTTGGAACATCTAGTCTACGGCGAAAAGCGCAGCTTT
TGCACTATAGAGATGATCTTGAGATTAGAGATTTAAGAGGCAATATTCAAACTAGACTGTCTAAGCTTGATAATGGTGAT
TATGATGCGATTATTTTAGCTAGTGCTGGACTTATTCGCTTAGAGTTAGTTGAGAGAATAACTCAGTTTATCCCTGTAGA
AATATCTTTACCAGCGGTAGGTCAAGGTATAGTAGTTATAGAGGCATTAGAGAGAGATAATGACCTTTTAGAAAAAATAC
AAAAATTAAATTGTAGAGAAAGTTCTCGTGTAGCAACAGCTGAGAGAGCTTTTAATCAAGAATTAAAAGGTGGCTGTCAT
GTTGCAATAGGTGCTTATGCAGAATTAGATAATAATCAGATAACCTTGATGGCAATGGTTGCAAGTAGTGATGGTAAGAA
AATTCTCAAGCGAAAGATGATTGGGGATGATCCTACTAAACTTGGTAAATTGTTAGCTCAAGAGATGATAGCACTAGGTG
CATATAAAATATTGGAGAGTTAA

Protein sequence :
MKQITIASRESKLALWQTNFVKNRIQLELNIPCEISTMKTQGDIILDQPLNKIGGKALFMKELEVAMLSNKADIAVHSLK
DVPYQLPQGFCLAGFMPREDPRDAFVSNKYNSIDDLPKGAVVGTSSLRRKAQLLHYRDDLEIRDLRGNIQTRLSKLDNGD
YDAIILASAGLIRLELVERITQFIPVEISLPAVGQGIVVIEALERDNDLLEKIQKLNCRESSRVATAERAFNQELKGGCH
VAIGAYAELDNNQITLMAMVASSDGKKILKRKMIGDDPTKLGKLLAQEMIALGAYKILES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-64 52
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-64 52