Gene Information

Name : iglB2 (FTF1713c)
Accession : YP_667751.1
Strain : Francisella tularensis FSC 198
Genome accession: NC_008245
Putative virulence/resistance : Virulence
Product : intracellular growth locus, subunit B
Function : -
COG functional category : S : Function unknown
COG ID : COG3517
EC number : -
Position : 1792460 - 1794004 bp
Length : 1545 bp
Strand : -
Note : Similar to AAP58963.1 (Q7X3J4) IglB from Francisella novicida (514 aa). BLAST Score = 997, Expect = 0.0 Identities = 496/514 (96), Positives = 499/514 (97). Identical to FTF1358. It is part of the duplicated region 1767715..1801625 which is identical to 1

DNA sequence :
ATGGTAAGTAGGGAGGATTTTATTATGACAATAAATAAATTAAGTCTCACTGATGAACTTTTAAATAATTTTGGGGGATC
TACAGAAGTTGATAGTGTACTCAAAAATATAGATTTTGATGTTTCAGATGATGCTTCTAAAGTTTTATCTTTATCTACTG
ACTACAATGCTAGAAACCTTATGGCGCTATCTTTGGTATTAGCAAATAATGATAATATAAATAATTATAATCAAAAATAT
ATCCAGAAAGTTATTACAGTTATTGATAAGCTTATTGATTTACAAGTTAATTCTATTATATCTAATGATGAGTTTAGAGC
ACTTGAGCAAGAATGGCTAAAGGTGCAAGAGGTTTGTCAAGAAGACTATGATAATGTTGAAGTAAGTATATTAGATGTAA
AAAAAGAAGAGCTACAATATGATTTCGAGAGAAATTTATATGATATATCTAGTAGTGACTTTTTCAAAAAAGTTTACGTT
TCAGAATTTGATCAATATGGTGGCGAACCTTATGGCGCAATATTAGGATTGTATAATTTTGAAAATACCACAAATGATAT
AATTTGGTTGACTGGAATGGGTATGGTGGCAAAGAATTCTCATGCACCATTTATTGCATCAATTGATAAGTCATTCTTTG
GTGTTAAGGATTTATCAGAAATCACTCATATAAAAAGTTTTGAAGCTTTGCTTGAGCATCCTAGATATAAAGAGTGGAAT
GATTTTAGAAACCTTGATGTTGCTGCATATATAGGTTTGACCGTAGGTGATTTTATGTTGCGGCAACCATATAATCCTGA
GAATAATCCAGTTCAGTATAAACTTATGGAAGGCTTTAATGAGTTTGTTGATTATGATAAGAATGAAAGTTATCTATGGG
GACCTGCTTCAATTCATCTAGTTAAGAATATGATGAGATCTTATGATAAAACTAGATGGTTCCAATATATAAGAGGAGTT
GAGAGTGGTGGTTATGTAAAGAACTTGGTAGCTTGCGTATATGATAATAAAGGCATTCTAGAAACTAAGTCACCTTTAAA
TGTATTATTCGCTGATTATATGGAGTTATCACTTGCAAATATTGGTTTAATACCATTTGTAAGTGAAAAAGGTACTAGTA
ACGCTTGTTTCTTTAGTGTAAATTCTGCTAAAAAAGTCGAAGAATTTGTAGATGGATTTGACTCAGCAAACTCAAGATTA
ATTGCTAACCTTTCTTACACTATGTGTATATCGAGAATATCTCATTATATTAAATGTGTAATTAGAGATAAGATTGGTAG
TATTGTGGATGTCGAGTCGATTCAAAAAATTCTTTCTGATTGGATATCAGAATTTGTCACCACAGTCTATCAACCAACCC
CTTTAGAAATGGCGAGATATCCTTTCAGAAACGTTTCTATCGAGGTTGAAACCATACCGGGTAAGCCTGGCTGGTATTCA
TGCAAAATAAATGTAATTCCCCACATTCAATTTGAAGGAATGAATACTACAATGACTATAGATACTAGGCTTGAACCAGA
ATTATTCGGTACAAATAATAACTAA

Protein sequence :
MVSREDFIMTINKLSLTDELLNNFGGSTEVDSVLKNIDFDVSDDASKVLSLSTDYNARNLMALSLVLANNDNINNYNQKY
IQKVITVIDKLIDLQVNSIISNDEFRALEQEWLKVQEVCQEDYDNVEVSILDVKKEELQYDFERNLYDISSSDFFKKVYV
SEFDQYGGEPYGAILGLYNFENTTNDIIWLTGMGMVAKNSHAPFIASIDKSFFGVKDLSEITHIKSFEALLEHPRYKEWN
DFRNLDVAAYIGLTVGDFMLRQPYNPENNPVQYKLMEGFNEFVDYDKNESYLWGPASIHLVKNMMRSYDKTRWFQYIRGV
ESGGYVKNLVACVYDNKGILETKSPLNVLFADYMELSLANIGLIPFVSEKGTSNACFFSVNSAKKVEEFVDGFDSANSRL
IANLSYTMCISRISHYIKCVIRDKIGSIVDVESIQKILSDWISEFVTTVYQPTPLEMARYPFRNVSIEVETIPGKPGWYS
CKINVIPHIQFEGMNTTMTIDTRLEPELFGTNNN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iglB1 YP_170310.1 intracellular growth locus subunit B Not tested FPI Protein 0.0 100
iglB2 YP_170618.1 intracellular growth locus subunit B Not tested FPI Protein 0.0 100
iglB AAP58963.1 IglB Virulence FPI Protein 0.0 99
iglB1 YP_001891777.1 intracellular growth locus protein B Virulence FPI Protein 0.0 99
iglB2 YP_001892272.1 intracellular growth locus protein B Virulence FPI Protein 0.0 99
iglB1 YP_001121163.1 intracellular growth locus B, IglB Virulence FPI Protein 0.0 99
iglB2 YP_001121566.1 intracellular growth locus iglB Virulence FPI Protein 0.0 99