Gene Information

Name : tktA (FTF1369c)
Accession : YP_667450.1
Strain : Francisella tularensis FSC 198
Genome accession: NC_008245
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1414812 - 1416803 bp
Length : 1992 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCTTTATCTATTCCACGCGAGTTTTCAAACGCTATAAGATTTTTATCTATTGATGCAACACTTAAAGCTAAATCAGG
ACATCCTGGAATGCCTATGGGGATGGCTGATATTGCCACAGTGTTATGGACAAAGTTTCTTAAGCACAATCCAAATAATC
CACATTGGATAAATAGAGATAGATTTGTTCTTTCAAATGGGCATGGCTCAATGCTTTTATATTCTCTGTTACATCTGACA
GGTTATGATCTATCTATTGAGGATATTAAAAATTTTAGGCAGTTACACTCAAAAACTCCAGGGCACCCTGAGTATGGCTA
TACGCCAGGAGTTGAGACAACAACTGGTCCATTAGGGCAAGGAGTAGCAAATGCTGTGGGTATGGCTTTAGGTGAAAAGC
TATTATCAGATAGGTATAATACACCTGATTTAAAAGTTATAGATCATCACACTTACGTGTTTTTAGGTGATGGATGTTTG
ATGGAGGGTGTTTCTCATGAAGCATGCTCATTAGCGGGGACTCTAGGTTTAAACAAATTAGTAGCATTTTGGGATGATAA
TAATATTTCGATAGATGGCGATACTAAGGGTTGGTTTAGTGATAATACACCTGAGAGATTTAGGGCGTATGGTTGGCATG
TTATAGAAAATGTTGATGGTCATGATTTTGTTGCGATTGAAAAAGCTATAAATGAAGCCCATTCTCAGCAGCAAAAACCA
ACTTTAATCTGTTGTAAAACTGTAATTGGTTTTGGCTCACCTGAGAAAGCTGGAACTGCCTCTGTGCATGGTTCGCCTTT
AAGTGATCAAGAAAGAGCCTCAGCTGCTAAAGAGCTTAACTGGGATTATCAAGCTTTTGAAATACCTCAAGATGTTTATA
AATACTGGGATGCTAGGGAAAAAGGACAAGCTTTAGAAGCAAATTGGCAAGGGCAATGGAATTTATTTAAAGACAGTCCT
AAGTTTGACGAATTTGAACGAGTTTTAAGTAAAGAGTTGCCAGTTGGATTAGAAAGCGCTATTAATGACTATATAGCTTC
GCAATTGAGTAATCCTGTCAAAGTGGCAACACGTAAAGCTTCACAAATGGTGCTTGAAGTCTTGTGTAAGAATATGCCTG
AGATGTTTGGTGGATCAGCAGATTTGACAGGATCAAATAATACTAATTGGAGTGGTTCAGTTTGGCTAAATAATACTCAA
GAAGGCGCAAATTATCTTTCTTATGGTGTTAGAGAGTTTGGTATGGCTGCAATAATGAATGGTCTAAGCCTTTATGGTGG
TATCAAACCTTATGGTGGTACATTCTTGGTATTTAGCGATTATTCAAGAAACGCGATAAGAATGTCAGCGTTGATGAAAC
AGCCTGTAGTTCATGTTATGTCGCATGACTCAATTGGTTTGGGAGAAGATGGACCAACTCATCAACCTATAGAACATGTT
CCGAGTTTAAGACTTATACCTAACTTAAGTGTTTGGCGACCTGCTGATACAATTGAAACAATGATAGCATGGAAAGAGGC
TGTAAAATCTAAAGATACGCCAAGTGTAATGGTACTTACACGTCAAAACTTAATGCCAGTAGTGCAAACACAGCATCAGG
TAGCAAATATTGCTAGAGGTGGTTATCTAGTTAAAGATAATCCTGATGCTAAATTAACTATTGTTGCTACTGGCTCTGAA
GTTGAGCTTGCTGTCAAAGTTGCTAATGAATTTGAAAAGAAAGGTATAAAATTAAATGTTGCTTCTATACCGTGTGTAGA
AGTTTTTGCTACTCAAGCTCACGAGTATAAAAAAACAGTAATAAAAGATGATATCCCGGCAGTTTTTGTTGAGATGGCGC
AACCTGATATGTGGTATAAATATATGCCAAAAGCAGGAGGGGAAGTAAAAGGAATCTATAGCTTTGGTGAGTCAGCACCG
GCTGAAGATTTATTTAAACGTTTTGGATTTACTGTAGAAAATATTAGCAATATTGTTGCTAAATATGTTTAA

Protein sequence :
MSLSIPREFSNAIRFLSIDATLKAKSGHPGMPMGMADIATVLWTKFLKHNPNNPHWINRDRFVLSNGHGSMLLYSLLHLT
GYDLSIEDIKNFRQLHSKTPGHPEYGYTPGVETTTGPLGQGVANAVGMALGEKLLSDRYNTPDLKVIDHHTYVFLGDGCL
MEGVSHEACSLAGTLGLNKLVAFWDDNNISIDGDTKGWFSDNTPERFRAYGWHVIENVDGHDFVAIEKAINEAHSQQQKP
TLICCKTVIGFGSPEKAGTASVHGSPLSDQERASAAKELNWDYQAFEIPQDVYKYWDAREKGQALEANWQGQWNLFKDSP
KFDEFERVLSKELPVGLESAINDYIASQLSNPVKVATRKASQMVLEVLCKNMPEMFGGSADLTGSNNTNWSGSVWLNNTQ
EGANYLSYGVREFGMAAIMNGLSLYGGIKPYGGTFLVFSDYSRNAIRMSALMKQPVVHVMSHDSIGLGEDGPTHQPIEHV
PSLRLIPNLSVWRPADTIETMIAWKEAVKSKDTPSVMVLTRQNLMPVVQTQHQVANIARGGYLVKDNPDAKLTIVATGSE
VELAVKVANEFEKKGIKLNVASIPCVEVFATQAHEYKKTVIKDDIPAVFVEMAQPDMWYKYMPKAGGEVKGIYSFGESAP
AEDLFKRFGFTVENISNIVAKYV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 57
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-180 55